2017
Seasonal Variability Precipitating Hand Transplant Rejection?
Lopdrup R, Turk M, Win T, Marty F, Molway D, Tullius S, Pomahac B, Talbot S. Seasonal Variability Precipitating Hand Transplant Rejection? Transplantation 2017, 101: e313. PMID: 28930103, DOI: 10.1097/tp.0000000000001877.Peer-Reviewed Original ResearchExperience With Patient Referrals for Upper Extremity Transplantation at a U.S. Academic Medical Center
Kiwanuka H, Aycart M, Bueno E, Pomahac B, Talbot S. Experience With Patient Referrals for Upper Extremity Transplantation at a U.S. Academic Medical Center. The Journal Of Hand Surgery 2017, 42: 751.e1-751.e6. PMID: 28648330, DOI: 10.1016/j.jhsa.2017.05.016.Peer-Reviewed Original ResearchConceptsUpper extremity transplantationMode of referralPhysician referralExtremity transplantationDemographic dataSelf-referred individualsSTUDY/LEVELInjury-related characteristicsPopulation of patientsU.S. academic medical centersUpper extremity disabilityClinical trial outcomesFisher's exact testAcademic medical centerChi-square testCommon indicationInjury characteristicsReferral patternsPatient referralTreatment modalitiesExtremity disabilityScreening practicesInstitutional experienceImmediate exclusionLevel IV
2016
Functional Outcomes after Bilateral Hand Transplantation
Singh M, Sisk G, Carty M, Sampson C, Blazar P, Dyer G, Earp B, Pribaz J, Pomahac B, Talbot S. Functional Outcomes after Bilateral Hand Transplantation. Plastic & Reconstructive Surgery 2016, 137: 185-189. PMID: 26710022, DOI: 10.1097/prs.0000000000001872.Peer-Reviewed Original ResearchConceptsBilateral hand transplantationHand transplantationFunctional outcomeHand scoreOutcome measuresShort Form-36 Health SurveyCLINICAL QUESTION/LEVELBilateral hand transplantMid-forearm levelFirst successful hand transplantationFunctional outcome measuresHand transplantHealth SurveyFunctional gainsTherapy measuresSystem scoreTransplantationPatientsScore systemMultiple studiesOutcomesScoresObjective scoresDisabilityConsiderable variability
2015
Initial Experience of Dual Maintenance Immunosuppression With Steroid Withdrawal in Vascular Composite Tissue Allotransplantation
Diaz-Siso J, Fischer S, Sisk G, Bueno E, Kueckelhaus M, Talbot S, Carty M, Treister N, Marty F, Milford E, Pomahac B, Tullius S. Initial Experience of Dual Maintenance Immunosuppression With Steroid Withdrawal in Vascular Composite Tissue Allotransplantation. American Journal Of Transplantation 2015, 15: 1421-1431. PMID: 25777324, DOI: 10.1111/ajt.13103.Peer-Reviewed Original ResearchConceptsAcute rejectionVCA recipientsMaintenance immunosuppressionSteroid-resistant acute rejectionLate acute rejectionSolid organ transplantationComposite tissue allotransplantationMaintenance steroidsTopical immunosuppressionCurrent immunosuppressionSteroid withdrawalBolus treatmentOrgan transplantationLow doseImmunosuppressionTissue allotransplantationInitial experienceFurther experienceSteroidsRecipientsTacrolimusPatientsTreatmentMonthsLow levels
2014
Hand transplants and the mandate for tolerance
Koulmanda M, Pomahac B, Fan Z, Murphy G, Strom T. Hand transplants and the mandate for tolerance. Current Opinion In Organ Transplantation 2014, Publish Ahead of Print: &na;. PMID: 25373855, PMCID: PMC4352932, DOI: 10.1097/mot.0000000000000138.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsGraft RejectionHand TransplantationHumansImmune ToleranceImmunologic MemoryInflammationInterleukin-2ConceptsHand transplantationIL-2Hand transplantLow-dose IL-2IL-2-based therapyBalance of immunityDrug-free toleranceRegulatory T cellsUse of immunosuppressionRecent clinical trialsLife-long immunosuppressionInduction of toleranceNonhuman primate modelShort-term treatmentDrug minimizationPosttransplant periodInflammatory processClinical trialsPrimate modelT cellsPreclinical demonstrationComposite allograftsAdverse inflammationTransplantationTransplantThe Value of Innovation
Dahlborg E, Diaz-Siso J, Bueno E, Sisk G, Pomahac B. The Value of Innovation. Plastic & Reconstructive Surgery 2014, 134: 178e-179e. PMID: 25028846, DOI: 10.1097/prs.0000000000000464.Peer-Reviewed Original ResearchFacial and Hand Allotransplantation
Pomahac B, Gobble R, Schneeberger S. Facial and Hand Allotransplantation. Cold Spring Harbor Perspectives In Medicine 2014, 4: a015651. PMID: 24478387, PMCID: PMC3935393, DOI: 10.1101/cshperspect.a015651.Peer-Reviewed Original ResearchConceptsVascularized Composite AllotransplantationFacial transplantationLong-term immunosuppressionMinimization of immunosuppressionGood functional outcomeTreatment of patientsMultidisciplinary team approachNovel therapeutic optionsSevere facial disfigurementAllograft survivalHand allotransplantationSkin rejectionTherapeutic optionsFunctional outcomeLimb lossComposite allotransplantationSide effectsTeam approachTransplantationSurgical planningFacial disfigurementImmunosuppressionAllotransplantationComplex proceduresPatients
2011
A Position Paper in Support of Hand Transplantation in the Blind
Carty M, Bueno E, Lehmann L, Pomahac B. A Position Paper in Support of Hand Transplantation in the Blind. Plastic & Reconstructive Surgery 2011, 128: 510e-515e. PMID: 22030511, DOI: 10.1097/prs.0b013e31822b62e7.Peer-Reviewed Original ResearchConceptsHand transplantation