2024
From standard therapies to monoclonal antibodies and immune checkpoint inhibitors – an update for reconstructive surgeons on common oncological cases
Knoedler L, Huelsboemer L, Hollmann K, Alfertshofer M, Herfeld K, Hosseini H, Boroumand S, Stoegner V, Safi A, Perl M, Knoedler S, Pomahac B, Kauke-Navarro M. From standard therapies to monoclonal antibodies and immune checkpoint inhibitors – an update for reconstructive surgeons on common oncological cases. Frontiers In Immunology 2024, 15: 1276306. PMID: 38715609, PMCID: PMC11074450, DOI: 10.3389/fimmu.2024.1276306.Peer-Reviewed Original ResearchConceptsImmune checkpoint inhibitorsHead and neck cancerBreast cancerMonoclonal antibodiesCheckpoint inhibitorsSkin cancerReconstructive surgeryNon-surgical treatment strategiesProlonged progression-free survivalSuboptimal treatment plansProgression-free survivalNon-surgical therapySurgical tumor resectionImpaired patient outcomeStandardized treatment algorithmSurgical therapy planningAnti-cancer strategyUnresectable tumorsConventional chemotherapyRemission rateTumor resectionCurative therapyTargeted therapyNeck cancerOncology cases
2008
Facial Transplantation and Immunosuppressed Patients: A New Frontier in Reconstructive Surgery
Pomahac B, Aflaki P, Chandraker A, Pribaz J. Facial Transplantation and Immunosuppressed Patients: A New Frontier in Reconstructive Surgery. Transplantation 2008, 85: 1693-1697. PMID: 18580458, DOI: 10.1097/tp.0b013e318176b29e.Peer-Reviewed Original ResearchConceptsPartial face transplantationOrgan transplant recipientsFace transplantationTransplant recipientsLife-long immunosuppressionPatient selection criteriaRisk of malignancyComposite tissue transplantationFacial transplantationAlternative reconstructive methodImmunosuppressive regimenImmunosuppressive therapyAdditional immunosuppressionSurgical resectionImmunosuppressed patientsOrgan recipientsPatient populationWomen's HospitalReconstructive surgeryTransplantationIRB approvalSkin cancerReconstructive methodsControversial procedureTissue transplantation