2018
Chronic rejection of human face allografts
Krezdorn N, Lian C, Wells M, Wo L, Tasigiorgos S, Xu S, Borges T, Frierson R, Stanek E, Riella L, Pomahac B, Murphy G. Chronic rejection of human face allografts. American Journal Of Transplantation 2018, 19: 1168-1177. PMID: 30312535, PMCID: PMC6433509, DOI: 10.1111/ajt.15143.Peer-Reviewed Original ResearchConceptsChronic rejectionComposite allograftsAutoimmune cutaneous disordersImmune-mediated changesLymphocyte-mediated cytotoxicityC-fosSevere facial disfigurementType IAcute rejectionSurveillance biopsiesIatrogenic immunosuppressionVascular ectasiaFollicular pluggingSystemic sclerosisHistopathologic evidenceClinical manifestationsPreventative therapyCutaneous disordersGraft durabilityFace allograftNasal mucosaPathologic changesPathologic alterationsEpidermal thinningSclerotic zone
2014
Airway Recovery after Face Transplantation
Fischer S, Wallins J, Bueno E, Kueckelhaus M, Chandawarkar A, Diaz-Siso J, Larson A, Murphy G, Annino D, Caterson E, Pomahac B. Airway Recovery after Face Transplantation. Plastic & Reconstructive Surgery 2014, 134: 946e-954e. PMID: 25415117, DOI: 10.1097/prs.0000000000000752.Peer-Reviewed Original ResearchConceptsAirway volumeUpper airwayFace transplantationRespiratory mucosaNasal passagesIncidence of sinusitisUpper airway infectionsUpper airway impairmentSevere facial injuriesQuality of lifeLife-altering consequencesAirway recoveryTracheostomy decannulationChronic coughAirway infectionFunctional airwayAirway impairmentNasal breathingTracheostomy tubeNasal mucosaSurgical correctionTomographic scanWomen's HospitalMucin productionFacial injuries