2024
Immunosuppressive strategies in face and hand transplantation: a comprehensive systematic review of current therapy regimens and outcomes
Huelsboemer L, Boroumand S, Kochen A, Dony A, Moscarelli J, Hauc S, Stögner V, Formica R, Pomahac B, Kauke-Navarro M. Immunosuppressive strategies in face and hand transplantation: a comprehensive systematic review of current therapy regimens and outcomes. Frontiers In Transplantation 2024, 3: 1366243. PMID: 38993787, PMCID: PMC11235358, DOI: 10.3389/frtra.2024.1366243.Peer-Reviewed Original ResearchCMV infectionImmunosuppressive regimensImmunosuppressive strategiesTransplant recipientsIncidence of rejection episodesClinical CMV infectionTriple maintenance therapyIncidence of rejectionEpisodes of rejectionIndividualized immunosuppressive regimensEffective immunosuppressive therapySystematic reviewFace transplant patientsHand transplant recipientsHand transplantationFacial graftImmunosuppressive therapyMaintenance therapyRejection episodesFacial mucosaGraft lossGraft rejectionTherapy regimensTransplant patientsRenal failure
2020
All hands on deck: Hand replantation versus transplantation
Heineman J, Bueno E, Kiwanuka H, Carty M, Sampson C, Pribaz J, Pomahac B, Talbot S. All hands on deck: Hand replantation versus transplantation. SAGE Open Medicine 2020, 8: 2050312120926351. PMID: 32537157, PMCID: PMC7268554, DOI: 10.1177/2050312120926351.Peer-Reviewed Original ResearchHand replantationAdverse events/side effectsSystematic reviewPatient satisfaction/qualityPost-operative considerationsDeterminants of outcomePre-operative considerationsMeta-Analyses (PRISMA) guidelinesSatisfaction/qualityPreferred Reporting ItemsBest possible outcomeUpper limb lossAcute amputationsSurgical repairHand transplantationSurgical techniqueOperative techniquePatient commitmentComplete amputationDaily livingForearm levelLimb lossPatient expectationsSide effectsBetter outcomes
2018
Pediatric face transplantation
Dorante M, Tasigiorgos S, Pomahac B. Pediatric face transplantation. Current Opinion In Organ Transplantation 2018, 23: 598-604. PMID: 30080696, DOI: 10.1097/mot.0000000000000572.Peer-Reviewed Original ResearchConceptsFace transplantationPediatric hand transplantationImmunosuppression burdenRejection episodesDonor allograftsPatient demographicsPediatric patientsAppropriate patientsHand transplantationHand transplantTransplantationPediatric colleaguesPatientsYoung populationFace transplantSurgical innovationTransplantOutcomes
2016
Functional Outcomes after Bilateral Hand Transplantation
Singh M, Sisk G, Carty M, Sampson C, Blazar P, Dyer G, Earp B, Pribaz J, Pomahac B, Talbot S. Functional Outcomes after Bilateral Hand Transplantation. Plastic & Reconstructive Surgery 2016, 137: 185-189. PMID: 26710022, DOI: 10.1097/prs.0000000000001872.Peer-Reviewed Original ResearchConceptsBilateral hand transplantationHand transplantationFunctional outcomeHand scoreOutcome measuresShort Form-36 Health SurveyCLINICAL QUESTION/LEVELBilateral hand transplantMid-forearm levelFirst successful hand transplantationFunctional outcome measuresHand transplantHealth SurveyFunctional gainsTherapy measuresSystem scoreTransplantationPatientsScore systemMultiple studiesOutcomesScoresObjective scoresDisabilityConsiderable variability
2015
Use of Video Clips to Assess the Outcomes of Bilateral Hand Transplantation
Singh M, Benjamin M, Turenne M, Lang G, Li H, Bueno E, Carty M, Pribaz J, Pomahac B, Talbot S. Use of Video Clips to Assess the Outcomes of Bilateral Hand Transplantation. Plastic & Reconstructive Surgery Global Open 2015, 3: e553. PMID: 26893978, PMCID: PMC4727705, DOI: 10.1097/gox.0000000000000539.Peer-Reviewed Original ResearchBilateral hand transplantationHand transplantationFunctional independenceStandardized time pointsNew scoring systemYears posttransplantationTransplantation patientsPeg TestIndex patientsRetrospective gradingFunctional assessmentTransplantationScoring systemPatientsLeft handTime pointsOutcomesMonthsScoring testPsychosocial Outcomes after Bilateral Hand Transplantation
Singh M, Oser M, Zinser J, Sisk G, Carty M, Sampson C, Pribaz J, Pomahac B, Talbot S. Psychosocial Outcomes after Bilateral Hand Transplantation. Plastic & Reconstructive Surgery Global Open 2015, 3: e533. PMID: 26579339, PMCID: PMC4634170, DOI: 10.1097/gox.0000000000000520.Peer-Reviewed Original ResearchHand transplantationPsychosocial outcomesNormal rangeBilateral hand transplantBilateral hand transplantationFirst successful hand transplantationEvidence of depressionDifferent time pointsSF-12Hand transplantSurgical techniquePsychosocial parametersEQ-5D.Patient screeningTransplant survivalTransplantationTime pointsMultiple reportsOutcomesPatientsDyadic Adjustment ScaleStandardized measurementsAdjustment ScaleScreeningOverall success
2014
Hand transplants and the mandate for tolerance
Koulmanda M, Pomahac B, Fan Z, Murphy G, Strom T. Hand transplants and the mandate for tolerance. Current Opinion In Organ Transplantation 2014, Publish Ahead of Print: &na;. PMID: 25373855, PMCID: PMC4352932, DOI: 10.1097/mot.0000000000000138.Peer-Reviewed Original ResearchConceptsHand transplantationIL-2Hand transplantLow-dose IL-2IL-2-based therapyBalance of immunityDrug-free toleranceRegulatory T cellsUse of immunosuppressionRecent clinical trialsLife-long immunosuppressionInduction of toleranceNonhuman primate modelShort-term treatmentDrug minimizationPosttransplant periodInflammatory processClinical trialsPrimate modelT cellsPreclinical demonstrationComposite allograftsAdverse inflammationTransplantationTransplant
2013
Rehabilitation Following Hand Transplantation
Bueno E, Benjamin M, Sisk G, Sampson C, Carty M, Pribaz J, Pomahac B, Talbot S. Rehabilitation Following Hand Transplantation. Hand 2013, 9: 9-15. PMID: 24570631, PMCID: PMC3928383, DOI: 10.1007/s11552-013-9568-8.Peer-Reviewed Original ResearchRehabilitation protocolHand transplantationRehabilitation therapyDaily living trainingUpper extremity amputeesMaximization of functionUnique needsUtility of interventionsHand allotransplantationMotion exercisesJoint contracturesTransplant operationScar adhesionFunctional assessmentNerve regenerationElectrical stimulationExtremity amputeesScar managementTherapy protocolsTransplantationTherapyHand protectionWound healingHand rehabilitationProgressive increase
2011
A Position Paper in Support of Hand Transplantation in the Blind
Carty M, Bueno E, Lehmann L, Pomahac B. A Position Paper in Support of Hand Transplantation in the Blind. Plastic & Reconstructive Surgery 2011, 128: 510e-515e. PMID: 22030511, DOI: 10.1097/prs.0b013e31822b62e7.Peer-Reviewed Original ResearchConceptsHand transplantation