2018
Increased levels of circulating MMP3 correlate with severe rejection in face transplantation
Kollar B, Shubin A, Borges T, Tasigiorgos S, Win T, Lian C, Dillon S, Gu X, Wyrobnik I, Murphy G, Pomahac B, Libermann T, Riella L. Increased levels of circulating MMP3 correlate with severe rejection in face transplantation. Scientific Reports 2018, 8: 14915. PMID: 30297859, PMCID: PMC6175842, DOI: 10.1038/s41598-018-33272-7.Peer-Reviewed Original ResearchConceptsSevere rejectionFace transplantationLarge independent patient cohortsAcute rejection episodesAnti-rejection treatmentFirst postoperative yearLongitudinal serum samplesNon-invasive candidate biomarkersViable treatment optionSOMAscan proteomics platformIndependent patient cohortsFace transplant recipientsRejection episodesPostoperative yearTransplant recipientsDevastating injuriesMMP3 levelsTransplant rejectionHistological gradePatient cohortTreatment optionsSurrogate markerMMP3 proteinCandidate biomarkersTransplantation
2013
Facial allotransplantation: A 3-year follow-up report
Diaz-Siso J, Parker M, Bueno E, Sisk G, Pribaz J, Eriksson E, Annino D, Tullius S, Pomahac B. Facial allotransplantation: A 3-year follow-up report. Journal Of Plastic Reconstructive & Aesthetic Surgery 2013, 66: 1458-1463. PMID: 23911716, DOI: 10.1016/j.bjps.2013.06.046.Peer-Reviewed Original ResearchConceptsQuality of lifeFunctional recoveryFace transplantationFirst postoperative yearPatients' functional recoveryPost-operative monthHigh-voltage burnsSatisfactory aesthetic resultsFace transplant patientsSevere facial defectsImmunosuppression dosesSteroid therapyPostoperative yearTransplant patientsMale patientsNormal sensationImmunologic complicationsWomen's HospitalMotor functionSurgical techniquePatient reportsReconstructive surgeryClose monitoringMultidisciplinary teamOccupational therapy