2019
Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation
Shubin A, Kollar B, Dillon S, Pomahac B, Libermann T, Riella L. Blood proteome profiling using aptamer-based technology for rejection biomarker discovery in transplantation. Scientific Data 2019, 6: 314. PMID: 31819064, PMCID: PMC6901551, DOI: 10.1038/s41597-019-0324-y.Peer-Reviewed Original ResearchConceptsDevastating facial injuriesSevere rejection episodesAcute transplant rejectionType of transplantationPeripheral blood serumSOMAscan proteomics platformSatisfactory treatment optionAcute rejectionRejection episodesTransplant statusTransplantation centersTransplant rejectionTreatment optionsBiomarker discoverySkin biopsiesClinical dataHigh riskFacial injuriesInvasive biomarkersTransplantationAptamer-based technologiesFace transplantationPatientsBlood serumSerum proteins
2016
Facial Transplantation
Aycart M, Alhefzi M, Kueckelhaus M, Fischer S, Dermietzel A, Wo L, Bueno E, Pribaz J, Pomahac B. Facial Transplantation. 2016, 5: 93-102. DOI: 10.1159/000444969.Peer-Reviewed Original ResearchAcute rejectionFacial transplantationDevastating facial injuriesPulse-dose corticosteroidsSolid organ transplantationThorough preoperative planningDonor pool expansionShort-term resultsPowerful clinical toolChronic rejectionDose corticosteroidsHost diseaseImmunomodulatory approachesGraft preservationCertain patientsFunctional outcomeOrgan transplantationFacial injuriesMultidisciplinary teamSensory functionClinical toolPatient safetyPreoperative planningPsychosocial outcomesTransplantationSurgical Optimization of Motor Recovery in Face Transplantation
Aycart M, Perry B, Alhefzi M, Bueno E, Kueckelhaus M, Fischer S, Pomahac B. Surgical Optimization of Motor Recovery in Face Transplantation. Journal Of Craniofacial Surgery 2016, 27: 286-292. PMID: 26967066, DOI: 10.1097/scs.0000000000002305.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolCleft LipCleft PalateCohort StudiesComorbidityCross InfectionFacial MusclesFacial NerveFacial TransplantationFemaleHospitals, PediatricHumansInfantInfant, NewbornMaleMotor NeuronsNerve TransferPlastic Surgery ProceduresPostoperative ComplicationsQuality ImprovementReoperationRetrospective StudiesRisk AdjustmentSmilingSurgical Wound InfectionConceptsMotor recoveryPatient 2Nerve transferNerve graftingPatient 1Devastating facial injuriesFacial nerve stumpFacial nerve reconstructionManual muscle testingFull face transplantIntraoperative soft tissueFacial nerve managementPrinciples of managementGradual improvementMuscle testingNerve reconstructionNerve stumpChallenging patientsMotor functionRetrospective analysisSensory restorationPatient's abilitySatisfactory motorFacial injuriesNerve management
2015
Facial transplantation
Wo L, Bueno E, Pomahac B. Facial transplantation. Current Opinion In Organ Transplantation 2015, Publish Ahead of Print: &na;. PMID: 26536422, DOI: 10.1097/mot.0000000000000253.Peer-Reviewed Original ResearchConceptsPositive HIV statusHIV statusFace transplantComposite allotransplantationUpper extremity transplantsDonor-specific antigensHistory of malignancyLatent viral infectionFacial transplantationChronic rejectionSimultaneous transplantationAbsolute contraindicationCase reportCurrent guidelinesFacial injuriesViral infectionTransplantTransplantationMedical teamAllotransplantationFirst face transplantFace transplantationFacial allotransplantationPatientsPsychological health
2014
Airway Recovery after Face Transplantation
Fischer S, Wallins J, Bueno E, Kueckelhaus M, Chandawarkar A, Diaz-Siso J, Larson A, Murphy G, Annino D, Caterson E, Pomahac B. Airway Recovery after Face Transplantation. Plastic & Reconstructive Surgery 2014, 134: 946e-954e. PMID: 25415117, DOI: 10.1097/prs.0000000000000752.Peer-Reviewed Original ResearchConceptsAirway volumeUpper airwayFace transplantationRespiratory mucosaNasal passagesIncidence of sinusitisUpper airway infectionsUpper airway impairmentSevere facial injuriesQuality of lifeLife-altering consequencesAirway recoveryTracheostomy decannulationChronic coughAirway infectionFunctional airwayAirway impairmentNasal breathingTracheostomy tubeNasal mucosaSurgical correctionTomographic scanWomen's HospitalMucin productionFacial injuries
2013
Vascularized Composite Allotransplantation and Tissue Engineering
Bueno E, Diaz-Siso J, Sisk G, Chandawarkar A, Kiwanuka H, Lamparello B, Caterson E, Pomahac B. Vascularized Composite Allotransplantation and Tissue Engineering. Journal Of Craniofacial Surgery 2013, 24: 256-263. PMID: 23348296, DOI: 10.1097/scs.0b013e318275f173.Peer-Reviewed Original ResearchConceptsTissue engineeringComposite tissue defectsTissue engineersVascularized Composite AllotransplantationDemonstrated resultsComposite tissueEngineeringTE researchImmune suppressionLifelong immune suppressionComposite allotransplantationAnatomic equivalentsTissue defectsBiomaterialsRegenerative medicineBioreactorCenter experienceExtremity amputationConventional reconstructionEngineersDonor shortageCompatible donorsFacial injuriesClinical practice