2018
The Collagenase of the Bacterium Clostridium histolyticum in the Treatment of Irradiation-Induced Capsular Contracture
Diehm Y, Hirche C, Berger M, Heil J, Golatta M, Kotsougiani D, Pomahac B, Kneser U, Fischer S. The Collagenase of the Bacterium Clostridium histolyticum in the Treatment of Irradiation-Induced Capsular Contracture. Aesthetic Plastic Surgery 2018, 43: 836-844. PMID: 30456640, DOI: 10.1007/s00266-018-1267-y.Peer-Reviewed Original ResearchConceptsBacterium Clostridium histolyticumCapsular fibrosisHematoma formationTreatment optionsImplant pocketClostridium histolyticumSilicone implantsMiniature silicone implantsNovel treatment optionsPotential treatment optionInjection of collagenaseVessel wall architectureMethodsThirty-six ratsVessel wall thicknessCollagenase injectionSignificant complicationsBreast reconstructionCapsular contractureClinical safetyBreast cancerDay 1Application of collagenaseDay 120Implant sitesThin capsule
2016
Extra-large negative pressure wound therapy dressings for burns – Initial experience with technique, fluid management, and outcomes
Fischer S, Wall J, Pomahac B, Riviello R, Halvorson E. Extra-large negative pressure wound therapy dressings for burns – Initial experience with technique, fluid management, and outcomes. Burns 2016, 42: 457-465. PMID: 26774601, DOI: 10.1016/j.burns.2015.08.034.Peer-Reviewed Original ResearchConceptsTotal body surface areaLength of stayWound infectionNPWT dressingsNegative pressure wound therapy dressingsExcision/graftingAcute kidney injuryBody surface areaRisk of infectionLarge burn woundsAverage graftKidney injuryFluid resuscitationIll patientsEarly outcomesImproved outcomesFluid managementWound careExtensive burnsDay 1PatientsWound sizeNPWTPatient careGraft