2024
Neural circuit disruptions of eye gaze processing in autism spectrum disorder and schizophrenia: An activation likelihood estimation meta-analysis
Ibrahim K, Iturmendi-Sabater I, Vasishth M, Barron D, Guardavaccaro M, Funaro M, Holmes A, McCarthy G, Eickhoff S, Sukhodolsky D. Neural circuit disruptions of eye gaze processing in autism spectrum disorder and schizophrenia: An activation likelihood estimation meta-analysis. Schizophrenia Research 2024, 264: 298-313. PMID: 38215566, PMCID: PMC10922721, DOI: 10.1016/j.schres.2023.12.003.Peer-Reviewed Original ResearchMeSH KeywordsAutism Spectrum DisorderBrainBrain MappingFixation, OcularHumansLikelihood FunctionsMagnetic Resonance ImagingSchizophreniaConceptsRight inferior frontal gyrusAutism spectrum disorderInferior frontal gyrusEye gaze processingActivation likelihood estimationRight fusiform gyrusGaze processingFrontal gyrusFusiform gyrusFrontotemporal circuitryFunctional decodingSpectrum disorderActivation Likelihood Estimation Meta-AnalysisMeta-analytic connectivity modelingMeta-analytic connectivityNeural circuit disruptionsTransdiagnostic biomarkerEmotional processingLeft amygdalaNeurobiological dysfunctionSocial cognitionEmotion perceptionNeural mechanismsSchizophreniaSpatial cognition
2023
The Selective Social Attention task in children with autism spectrum disorder: Results from the Autism Biomarkers Consortium for Clinical Trials (ABC‐CT) feasibility study
Shic F, Barney E, Naples A, Dommer K, Chang S, Li B, McAllister T, Atyabi A, Wang Q, Bernier R, Dawson G, Dziura J, Faja S, Jeste S, Murias M, Johnson S, Sabatos‐DeVito M, Helleman G, Senturk D, Sugar C, Webb S, McPartland J, Chawarska K, Trials T. The Selective Social Attention task in children with autism spectrum disorder: Results from the Autism Biomarkers Consortium for Clinical Trials (ABC‐CT) feasibility study. Autism Research 2023, 16: 2150-2159. PMID: 37749934, PMCID: PMC11003770, DOI: 10.1002/aur.3026.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSocial attention taskSchool-aged childrenAttention taskASD groupSpectrum disorderEye-tracking taskTotal T-scoreAttentional patternsAutism spectrumTD groupPresentation timeTrial feasibility studyGroup differencesPercent of timeOlder childrenTaskComparison groupToddlersT-scoreChildrenChildren 4Outcome variablesFaceCondition effects
2022
Neural correlates of eye contact and social function in autism spectrum disorder
Hirsch J, Zhang X, Noah J, Dravida S, Naples A, Tiede M, Wolf J, McPartland J. Neural correlates of eye contact and social function in autism spectrum disorder. PLOS ONE 2022, 17: e0265798. PMID: 36350848, PMCID: PMC9645655, DOI: 10.1371/journal.pone.0265798.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderDorsal parietal regionsNeural correlatesEye contactLive eyesNeural responsesSpectrum disorderAutism Diagnostic Observation ScheduleUnderlying neural correlatesSocial Responsiveness ScaleGold standard measureCentral diagnostic criterionDiagnostic criteriaDiagnostic biomarkersSRS-2ADOS-2Responsiveness ScaleObservation ScheduleParietal regionsPupillometry dataNeural systemsEyesNatural interactionDisordersCorrelatesFunctional but not obligatory link between microsaccades and neural modulation by covert spatial attention
Liu B, Nobre A, van Ede F. Functional but not obligatory link between microsaccades and neural modulation by covert spatial attention. Nature Communications 2022, 13: 3503. PMID: 35715471, PMCID: PMC9205986, DOI: 10.1038/s41467-022-31217-3.Peer-Reviewed Original ResearchConceptsCompared to trialsSpatial attentionCovert spatial attentionModulation of alpha activityVisual working memoryModulation of neural activitySpatial modulationNeural modulationEEG alpha activityAlpha activityWorking memoryNeural signaturesNeural activityDirectional biasMemorised locationEye movementsFixational eye movementsMicrosaccades
2021
Increasing Central Serotonin with 5-hydroxytryptophan Disrupts the Inhibition of Social Gaze in Nonhuman Primates
Weinberg-Wolf HB, Fagan N, Dal Monte O, Chang SWC. Increasing Central Serotonin with 5-hydroxytryptophan Disrupts the Inhibition of Social Gaze in Nonhuman Primates. Journal Of Neuroscience 2021, 42: 670-681. PMID: 34862190, PMCID: PMC8805615, DOI: 10.1523/jneurosci.0413-21.2021.Peer-Reviewed Original ResearchConceptsSocial gaze behaviorAbility of monkeysSocial gazeGaze behaviorMotivational stateControl imagesReaction timeCentral serotonin levelsNonhuman primatesSocial orientingGaze responsesSerotonergic interventionsModulatory relationshipCausal evidenceEye movementsTranslational insightsGazeDistinct aspectsDisruptive effectsBehavioral changesSerotonergic systemPupil constrictionCausal impactCentral serotoninFlexible orientation
2020
Facial and neural mechanisms during interactive disclosure of biographical information
Cañigueral R, Zhang X, Noah JA, Tachtsidis I, Hamilton AFC, Hirsch J. Facial and neural mechanisms during interactive disclosure of biographical information. NeuroImage 2020, 226: 117572. PMID: 33221448, PMCID: PMC7612862, DOI: 10.1016/j.neuroimage.2020.117572.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCerebral CortexDisclosureEye Movement MeasurementsFacial ExpressionFacial MusclesFemaleFixation, OcularFunctional NeuroimagingHumansMaleMiddle AgedParietal LobePrefrontal CortexSelf DisclosureSignal Processing, Computer-AssistedSocial InteractionSpectroscopy, Near-InfraredTemporal LobeYoung AdultConceptsNeurocognitive mechanismsFacial displaysCommunicative interactionMore eye gazeNon-interactive situationsPairs of participantsBiographical informationBilateral TPJRight TPJLeft SMGNeuroscience hypothesisNeural mechanismsEye gazeMultimodal findingsBrain activitySocial signalingTPJDLPFCMutual sharingParticipantsSpontaneous productionLong-range mechanismsGazeDisplaySynchronyConverging Multi-modal Evidence for Implicit Threat-Related Bias in Pediatric Anxiety Disorders
Abend R, Bajaj MA, Matsumoto C, Yetter M, Harrewijn A, Cardinale EM, Kircanski K, Lebowitz ER, Silverman WK, Bar-Haim Y, Lazarov A, Leibenluft E, Brotman M, Pine DS. Converging Multi-modal Evidence for Implicit Threat-Related Bias in Pediatric Anxiety Disorders. Research On Child And Adolescent Psychopathology 2020, 49: 227-240. PMID: 33095373, PMCID: PMC7839316, DOI: 10.1007/s10802-020-00712-w.Peer-Reviewed Original ResearchConceptsPediatric anxiety disordersAnxiety disordersThreat biasImplicit biasHealthy peersImplicit bias measuresMulti-modal evidenceTask performanceBias measuresNegative relativeWhole-body movementsMultiple tasksTaskImplicit threatFuture researchPeersGreater tendencyDisordersFaceBiasAnxietyYouthThreatMeasuresEvidence
2019
Eye-tracking during simulation-based neonatal airway management
Wagner M, Gröpel P, Bibl K, Olischar M, Auerbach MA, Gross IT. Eye-tracking during simulation-based neonatal airway management. Pediatric Research 2019, 87: 518-522. PMID: 31499516, DOI: 10.1038/s41390-019-0571-9.Peer-Reviewed Original ResearchConceptsEye-tracking glassesAirway managementNeonatal airway managementUmbilical vein catheterMain outcome measuresAirway providersMedical tasksVein catheterNeonatal resuscitationOutcome measuresMethodsThis studySimulation-based studyProvider behaviorUsabilityGaze behaviorSignificant differencesReal situationIdeal useFuture studiesProvidersParticipantsTeam membersTime of interestManagementCatheterPromoting social attention in 3‐year‐olds with ASD through gaze‐contingent eye tracking
Wang Q, Wall CA, Barney EC, Bradshaw JL, Macari SL, Chawarska K, Shic F. Promoting social attention in 3‐year‐olds with ASD through gaze‐contingent eye tracking. Autism Research 2019, 13: 61-73. PMID: 31468735, PMCID: PMC7256927, DOI: 10.1002/aur.2199.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderCue groupPost trainingGaze-contingent trainingNon-ASD peersLow nonverbal abilityDecrease of attentionLarger training effectsGreater cognitive impairmentCurrent behavioral interventionsNonverbal abilityCue conditionTD controlsAttention difficultiesSpectrum disorderSocial learningBehavioral interventionsTraining effectsCognitive impairmentYoung childrenPre trainingSocial characterChildrenTrainingFaceThe role of limited salience of speech in selective attention to faces in toddlers with autism spectrum disorders
Shic F, Wang Q, Macari SL, Chawarska K. The role of limited salience of speech in selective attention to faces in toddlers with autism spectrum disorders. Journal Of Child Psychology And Psychiatry 2019, 61: 459-469. PMID: 31471912, PMCID: PMC7048639, DOI: 10.1111/jcpp.13118.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderDirect gazeAutism symptomsSpectrum disorderImpact of speechAudiovisual speechSelective attentionSpeech cuesTD toddlersNonverbal skillsNonverbal levelEye contactEye trackingPoor attentionInteractive partnersEye regionMouth regionSpeechToddlersSalienceLimited salienceNovel treatment targetsEarly childhoodCuesTreatment targetsHuman gaze tracks attentional focusing in memorized visual space
van Ede F, Chekroud S, Nobre A. Human gaze tracks attentional focusing in memorized visual space. Nature Human Behaviour 2019, 3: 462-470. PMID: 31089296, PMCID: PMC6546593, DOI: 10.1038/s41562-019-0549-y.Peer-Reviewed Original ResearchTwelve-month-old infants’ attention to the eyes of a talking face is associated with communication and social skills
Pons F, Bosch L, Lewkowicz D. Twelve-month-old infants’ attention to the eyes of a talking face is associated with communication and social skills. Infant Behavior And Development 2019, 54: 80-84. PMID: 30634137, DOI: 10.1016/j.infbeh.2018.12.003.Peer-Reviewed Original ResearchMeSH KeywordsAttentionCommunicationFacial ExpressionFemaleFixation, OcularHumansInfantMalePhotic StimulationSocial SkillsSpeech PerceptionConceptsTalker's eyesTwelve-month-old infantsAdaptive behaviour questionnaireInfant attentionSocial abilitiesSocial skillsEye gazeBSID-IIICommunication subscaleToddler DevelopmentBayley ScalesMonth old infantsBehavior QuestionnairePositive relationshipAttentionTobiiGazeSubscalesSkillsScoresSocialInfantsCommunicationFaceQuestionnaire
2018
Development of Adaptive Communication Skills in Infants of Blind Parents
Ganea N, Hudry K, Vernetti A, Tucker L, Charman T, Johnson MH, Senju A. Development of Adaptive Communication Skills in Infants of Blind Parents. Developmental Psychology 2018, 54: 2265-2273. PMID: 30335435, PMCID: PMC6254470, DOI: 10.1037/dev0000564.Peer-Reviewed Original ResearchInside bilingualism: Language background modulates selective attention to a talker's mouth
Birulés J, Bosch L, Brieke R, Pons F, Lewkowicz D. Inside bilingualism: Language background modulates selective attention to a talker's mouth. Developmental Science 2018, 22: e12755. PMID: 30251757, DOI: 10.1111/desc.12755.Peer-Reviewed Original ResearchConceptsTalker's mouthSpanish-learning infantsAudiovisual speech cuesClose languagesLanguage proximityLanguage backgroundEnglish monologuesMonolingual infantsSelective attentionTalker's eyesBilingualsLanguageCatalanGreater salienceSpeech cuesAudiovisual cuesSuch cuesCuesBilingualismMonologueEarly childhoodPrevious findingsAttentionTalkersGreat attentionTowards optimal visual presentation design for hybrid EEG—fTCD brain–computer interfaces
Khalaf A, Sejdic E, Akcakaya M. Towards optimal visual presentation design for hybrid EEG—fTCD brain–computer interfaces. Journal Of Neural Engineering 2018, 15: 056019. PMID: 30021931, DOI: 10.1088/1741-2552/aad46f.Peer-Reviewed Original ResearchConceptsFunctional transcranial Doppler ultrasoundMental rotationTerms of accuracyTransfer rateFTCD signalsHybrid systemDesign approachReal-time BCIVisual presentationFeasible candidateMotor imageryInterface systemHigh accuracyVisual stimulation techniqueElectrical brain activityBrain-computer interface (BCI) systemsHybrid BCIHybrid combinationCognitive tasksPower spectrumSuch promising resultsHybrid brain-computer interface (BCI) systemFixation crossAccuracyDesignInfant neural sensitivity to eye gaze depends on early experience of gaze communication
Vernetti A, Ganea N, Tucker L, Charman T, Johnson MH, Senju A. Infant neural sensitivity to eye gaze depends on early experience of gaze communication. Developmental Cognitive Neuroscience 2018, 34: 1-6. PMID: 29890461, PMCID: PMC6252267, DOI: 10.1016/j.dcn.2018.05.007.Peer-Reviewed Original ResearchConceptsEvent-related potentialsGaze shiftsBrain responsesGaze communicationDynamic gaze shiftsInfant neural sensitivitySelective brain responsesFunctional brain developmentEye-gaze communicationBlind parentsNeural sensitivitySighted infantsEye gazeSighted parentsCommunicative experiencesPrimary caregiversHuman brainDistinct experiencesCommunication experiencesIndividual environmentsCurrent studyBrain developmentParentsEarly experienceFunctional specialisationOperationalizing atypical gaze in toddlers with autism spectrum disorders: a cohesion-based approach
Wang Q, Campbell DJ, Macari SL, Chawarska K, Shic F. Operationalizing atypical gaze in toddlers with autism spectrum disorders: a cohesion-based approach. Molecular Autism 2018, 9: 25. PMID: 29651331, PMCID: PMC5894192, DOI: 10.1186/s13229-018-0211-y.Peer-Reviewed Original ResearchThe redeployment of attention to the mouth of a talking face during the second year of life
de Boisferon A, Tift A, Minar N, Lewkowicz D. The redeployment of attention to the mouth of a talking face during the second year of life. Journal Of Experimental Child Psychology 2018, 172: 189-200. PMID: 29627481, PMCID: PMC5920681, DOI: 10.1016/j.jecp.2018.03.009.Peer-Reviewed Original ResearchMeSH KeywordsAttentionCuesFaceFemaleFixation, OcularHumansInfantMaleMouthSpeech PerceptionVerbal LearningConceptsTalker's mouthSpeech cuesAdult-directed mannerAudiovisual speech cuesWord learning phaseGreater perceptual salienceMonolingual infantsAttentional focusMonolingual EnglishPerceptual salienceEye gazeSpanish utterancesNative languageAcquisition phaseSpeech formsMonths of ageUtterancesCuesAttentionTalkersFaceSalienceGazeLexiconInfantsThe effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque
Weinberg-Wolf H, Fagan NA, Anderson GM, Tringides M, Dal Monte O, Chang SWC. The effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque. Neuropsychopharmacology 2018, 43: 1589-1598. PMID: 29463909, PMCID: PMC5983545, DOI: 10.1038/s41386-017-0003-7.Peer-Reviewed Original ResearchConceptsSerotonergic interventionsSalient facial featuresCentral serotonergic functioningCisternal cerebrospinal fluidBaseline attentionCognitive operationsSerotonin's roleIndividual differencesBi-directional effectsAutonomic arousalSaline sessionsImmediate serotonin precursorEngaged individualsBehavioral impairmentsFacial featuresSerotonergic functioningStimulus animalsRole of serotoninPupil sizeAnxietyPsychiatric disordersSerotonin neurochemistrySerotoninergic functionSerotonin effectsCSF concentrations
2017
Simulating interaction: Using gaze-contingent eye-tracking to measure the reward value of social signals in toddlers with and without autism
Vernetti A, Senju A, Charman T, Johnson MH, Gliga T, Team T. Simulating interaction: Using gaze-contingent eye-tracking to measure the reward value of social signals in toddlers with and without autism. Developmental Cognitive Neuroscience 2017, 29: 21-29. PMID: 28939027, PMCID: PMC6987892, DOI: 10.1016/j.dcn.2017.08.004.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderHR-ASD groupLow-risk controlsSocial interactionDiagnosis of ASDNaturalistic social interactionsLow familial riskSocial orientingSocial motivationASD diagnosisReward valueSocial signalsSpectrum disorderSocial videosAge 3Mechanical toysFamilial riskAge 2ToddlersPersonsOrientingAutismDifficultiesRewardMotivation
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply