2023
“We All Want to Be Able to Tell You Something Hopeful”: Clinicians’ Experiences Providing Maternal-Fetal Surgery Counseling
Wilpers A, Hyatt E, Bahtiyar M, Hu Y, Leon-Martinez D, Chervenak F, McCoyd J. “We All Want to Be Able to Tell You Something Hopeful”: Clinicians’ Experiences Providing Maternal-Fetal Surgery Counseling. Fetal Diagnosis And Therapy 2023, 50: 353-367. PMID: 37315537, DOI: 10.1159/000531535.Peer-Reviewed Original ResearchMaternal-fetal surgeryPregnant peopleMaternal-fetal medicine specialistsNon-Hispanic whitesMethods cliniciansInterpretive description methodPediatric subspecialistsInterprofessional cliniciansClinician experiencePediatric surgeonsMedicine specialistsSupportive counselingSurgeryPrenatal counselingPractice differencesCliniciansCounselingMore evidenceGenetic counselorsOverarching themesParticipantsNeonatologistsCounseling practiceSubspecialistsNursesCausal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia
Blette B, Granholm A, Li F, Shankar-Hari M, Lange T, Munch M, Møller M, Perner A, Harhay M. Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia. Scientific Reports 2023, 13: 6570. PMID: 37085591, PMCID: PMC10120498, DOI: 10.1038/s41598-023-33425-3.Peer-Reviewed Original ResearchConceptsCritical COVID-19Better long-term outcomesCOVID-19Entire trial populationStandardized dosing protocolsMultiple patient characteristicsDose of dexamethasoneLong-term outcomesIL-6 inhibitorsDexamethasone doseSevere hypoxemiaMost patientsPatient characteristicsRespiratory supportDiabetes mellitusClinical outcomesDosing protocolTrial populationTreatment effect heterogeneityPatient featuresPatientsAdditional studiesDexamethasoneDoseMore evidenceProtein degraders enter the clinic — a new approach to cancer therapy
Chirnomas D, Hornberger K, Crews C. Protein degraders enter the clinic — a new approach to cancer therapy. Nature Reviews Clinical Oncology 2023, 20: 265-278. PMID: 36781982, PMCID: PMC11698446, DOI: 10.1038/s41571-023-00736-3.Peer-Reviewed Original ResearchConceptsPhase III trialsCancer therapyNovel therapeutic modalitiesIII trialsClinical trialsPreclinical modelsClinical studiesTherapeutic modalitiesPharmacokinetic dataSmall molecule inhibitorsDisease pathogenesisClinical testingTumor typesDrug concentrationsPreclinical researchCancer treatmentPhase IFirst safetyUbiquitin-proteasome systemPatientsProtein degradersTherapyMore evidenceTrialsRigorous evaluationPotential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions
Mestre-Bach G, Potenza M. Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions. Nutrients 2023, 15: 827. PMID: 36839185, PMCID: PMC9962023, DOI: 10.3390/nu15040827.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInternet gaming disorderGambling disorderVentral striatumBehavioral addictionsBinge Eating DisorderReward processingEating DisordersGaming disorderReward systemTreatment implicationsBrain regionsBrain changesTreatment-related changesAddictionDisordersBingePotential biological markersPossible biomarkersBiological markersMore evidenceSpecific roleProcessingInterventionImplicationsCircuitry
2022
Long-Term Complications of COVID-19 Infection in Adolescents and Children
Thallapureddy K, Thallapureddy K, Zerda E, Suresh N, Kamat D, Rajasekaran K, Moreira A. Long-Term Complications of COVID-19 Infection in Adolescents and Children. Current Pediatrics Reports 2022, 10: 11-17. PMID: 35127274, PMCID: PMC8803461, DOI: 10.1007/s40124-021-00260-x.Peer-Reviewed Original ResearchLong COVIDSARS-CoV-2 infectionPersistent COVID-19 symptomsLong COVID-19Long COVID symptomsSymptomatic COVID-19COVID-19 infectionCOVID-19 symptomsHealth care providersCOVID-19Recent FindingsChildrenPersistent symptomsTerm complicationsPediatric populationCOVID symptomsCare providersSymptomsOlder childrenChildrenAdultsInfectionMore evidenceAdolescentsCOVIDPotential effects
2018
Are Neuropeptide-Reactive T Cells behind Narcolepsy?
Deerhake ME, Barclay WE, Shinohara ML. Are Neuropeptide-Reactive T Cells behind Narcolepsy? Immunity 2018, 49: 796-798. PMID: 30462995, DOI: 10.1016/j.immuni.2018.11.002.Peer-Reviewed Original Research
2015
Achieving best outcomes for patients with cardiovascular disease in China by enhancing the quality of medical care and establishing a learning health-care system
Jiang L, Krumholz HM, Li X, Li J, Hu S. Achieving best outcomes for patients with cardiovascular disease in China by enhancing the quality of medical care and establishing a learning health-care system. The Lancet 2015, 386: 1493-1505. PMID: 26466053, PMCID: PMC5323019, DOI: 10.1016/s0140-6736(15)00343-8.Peer-Reviewed Original Research
2008
Periprocedural Drug Therapy in Carotid Artery Stenting: The Need for More Evidence
Gortler D, Schlösser FJ, Muhs BE, Nelson MA, Dardik† A. Periprocedural Drug Therapy in Carotid Artery Stenting: The Need for More Evidence. Vascular 2008, 16: 303-309. PMID: 19344586, DOI: 10.2310/6670.2008.00081.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCarotid endarterectomyLarge prospective cohort studyDual antiplatelet therapyProspective cohort studyCarotid artery stentingCohort studyArtery stentingPeriprocedural settingDrug therapyPharmacologic agentsCarotid arteryHigh riskPatient careTherapyOptimal outcomesRegimenGood validityPatientsMore evidenceOutcomesOptimal timeClopidogrelEndarterectomyMedicationsStenting
2004
More Evidence for Reach Out and Read: A Home-Based Study
Weitzman CC, Roy L, Walls T, Tomlin R. More Evidence for Reach Out and Read: A Home-Based Study. 2004, 113: 1248-1253. PMID: 15121937, DOI: 10.1542/peds.113.5.1248.Peer-Reviewed Original ResearchConceptsImportant confoundersHome visitsPrimary care centersWell-child carePediatric well-child careWell-child visitsCross-sectional studyHierarchical linear regressionCare centerMedical recordsHome environmentReach OutParent interviewsVisitsLinear regressionROR programConfoundersChildrenParent reportTotalMore evidenceStandardized measuresLiteracy profilesHome ObservationLiteracy interventions
1999
Short rib‐polydactyly syndrome: more evidence of a continuous spectrum
Sarafoglou K, Funai E, Fefferman N, Zajac L, Geneiser N, Paidas M, Greco A, Wallerstein R. Short rib‐polydactyly syndrome: more evidence of a continuous spectrum. Clinical Genetics 1999, 56: 145-148. PMID: 10517252, DOI: 10.1034/j.1399-0004.1999.560209.x.Peer-Reviewed Original Research
1996
Economic Evaluation of HIV Testing Among Intravenous Drug Users: An Analytic Framework and Its Application to Italy
Villari P, Fattore G, Siegel J, Paltiel A, Weinstein M. Economic Evaluation of HIV Testing Among Intravenous Drug Users: An Analytic Framework and Its Application to Italy. International Journal Of Technology Assessment In Health Care 1996, 12: 336-357. PMID: 8707505, DOI: 10.1017/s0266462300009673.Peer-Reviewed Original ResearchConceptsIntravenous drug usersEarly treatmentDrug usersHIV testing programsLife expectancyEffective early treatmentLow prevalence scenariosHealth care interventionsYears of lifeCost-effectiveness analysisHIV testingAsymptomatic subjectsCare interventionsPrevalence areasHigh prevalenceEconomic evaluationCost-effective procedureHIVPrevalenceTreatmentMore evidenceBehavior changeExpectancyCost savingsCohort
1994
Dietary lactose intake, lactose intolerance, and the risk of epithelial ovarian cancer in southern Ontario (Canada)
Risch H, Jain M, Marrett L, Howe G. Dietary lactose intake, lactose intolerance, and the risk of epithelial ovarian cancer in southern Ontario (Canada). Cancer Causes & Control 1994, 5: 540-548. PMID: 7827241, DOI: 10.1007/bf01831382.Peer-Reviewed Original ResearchConceptsOral contraceptive useOvarian cancerContraceptive useLactose intoleranceTotal daily caloric intakeFull-term pregnancyEpithelial ovarian cancerCase-control studyDaily caloric intakeQuantitative diet historyDietary factorsLactose intakeCaloric intakeProtective effectDiet historyAge groupsCancerDaily consumptionIntoleranceIntakeTotal durationIntake valuesPopulation controlsRiskMore evidence
1980
On Terminating Psychotherapy: More Evidence of Sex-Role Related Countertransference
Greene L. On Terminating Psychotherapy: More Evidence of Sex-Role Related Countertransference. Psychology Of Women Quarterly 1980, 4: 548-557. DOI: 10.1111/j.1471-6402.1980.tb00725.x.Peer-Reviewed Original Research
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