2024
Impact of Sodium-Glucose Cotransporter-2 Inhibitors in the Management of Chronic Kidney Disease: A Middle East and Africa Perspective
Elkeraie A, Al-Ghamdi S, Abu-Alfa A, Alotaibi T, AlSaedi A, AlSuwaida A, Arici M, Ecder T, Ghnaimat M, Hafez M, Hassan M, Sqalli T. Impact of Sodium-Glucose Cotransporter-2 Inhibitors in the Management of Chronic Kidney Disease: A Middle East and Africa Perspective. International Journal Of Nephrology And Renovascular Disease 2024, 17: 1-16. PMID: 38196830, PMCID: PMC10771977, DOI: 10.2147/ijnrd.s430532.Peer-Reviewed Original ResearchChronic kidney diseaseSodium-glucose cotransporter 2 inhibitorsCotransporter 2 inhibitorsDiabetes mellitusKidney diseaseType 2 diabetes mellitusMajor public health concernAldosterone system inhibitorsBetter clinical outcomesCause of deathPublic health concernNephrology referralCKD managementClinical outcomesSystem inhibitorsCardioprotective propertiesEarly initiationTreatment pathwaysConsensus recommendationsHigh riskPatientsBetter careHealth concernEarly detectionHypertension
2023
Opioid use disorder amongst young people living with HIV: A 10-year trend
Ikekwere J, Eiger R, Heward B, Longcoy J, Okobi O, Oladunjoye A, Onyeaka H, Kompella S, Jegede O. Opioid use disorder amongst young people living with HIV: A 10-year trend. Psychiatry Research Communications 2023, 3: 100140. DOI: 10.1016/j.psycom.2023.100140.Peer-Reviewed Original ResearchOpioid use disorderMental health diagnosesUse disordersDiagnosis of OUDRisk of OUDNational Inpatient Sample dataMajor public health concernNew HIV diagnosesMultivariable logistic regressionMental health servicesHIV-positive young peoplePublic health concernMental health issuesComorbid HIVHIV diagnosisOpioid useOUD diagnosisEffective treatmentHigh riskHIVPrevention strategiesICD codesTargeted preventionDrug useHealth servicesDeveloping non-opioid therapeutics to alleviate pain among persons with opioid use disorder: a review of the human evidence
Oliveira D, Fontenele R, Weleff J, Sofuoglu M, De Aquino J. Developing non-opioid therapeutics to alleviate pain among persons with opioid use disorder: a review of the human evidence. International Review Of Psychiatry 2023, 35: 377-396. PMID: 38299655, PMCID: PMC10835074, DOI: 10.1080/09540261.2023.2229430.Peer-Reviewed Original ResearchOpioid agonist therapyOpioid use disorderNon-opioid analgesicsUse disordersNon-opioid analgesic therapyAlpha-2 adrenergic agonistsMajor public health concernGlial activation inhibitorNon-opioid therapeuticsNovel analgesic strategiesPotential of cannabinoidsPrior opioid exposureOpioid-dependent individualsOpioid-dependent populationsAbuse liability assessmentPublic health concernAnalgesic strategiesAgonist therapyAnalgesic therapyOpioid exposureOUD treatmentPharmacokinetic interactionsGABAergic drugsSignificant morbidityPain typesSecondary Ischemic Stroke Prevention
Bangad A, Abbasi M, de Havenon A. Secondary Ischemic Stroke Prevention. Neurotherapeutics 2023, 20: 721-731. PMID: 36877331, PMCID: PMC10275832, DOI: 10.1007/s13311-023-01352-w.Peer-Reviewed Original ResearchConceptsSecondary ischemic stroke preventionIschemic stroke preventionRecurrent ischemic strokeStroke preventionIschemic strokeRisk factorsMajor public health concernSecondary stroke preventionLifestyle risk factorsVascular risk factorsRecurrent stroke riskAvailability of treatmentPublic health concernHealth care systemAHA guidelinesStroke riskSurgical treatmentHealth burdenPatient burdenFirst strokeStrokeHealth concernCare systemPreventionTreatment
2022
Individual and regional characteristics associated with changes in mental health before and during the COVID-19 pandemic in South Korea
Min J, Kwon D, Lee W, Kang C, Park C, Heo S, Bell M, Kim H. Individual and regional characteristics associated with changes in mental health before and during the COVID-19 pandemic in South Korea. Scientific Reports 2022, 12: 14189. PMID: 35986083, PMCID: PMC9390104, DOI: 10.1038/s41598-022-18493-1.Peer-Reviewed Original ResearchConceptsMental healthCOVID-19 pandemicMajor public health concernPublic health concernMental health outcomesMental health consequencesEpidemiological evidencePhysical activityHealth outcomesHigher household incomeHealth consequencesHealth concernHigher education levelCOVID-19DepressionPositive associationTime trendsPrevalenceHealthEducation levelModerate stressPandemicExtreme stressAssociationHousehold incomeTrauma as a Public Health Issue: Epidemiology of Trauma and Trauma-Related Disorders
Mew E, Koenen K, Lowe S. Trauma as a Public Health Issue: Epidemiology of Trauma and Trauma-Related Disorders. 2022, 13-40. DOI: 10.1007/978-3-030-97802-0_2.Peer-Reviewed Original ResearchTrauma-related disordersGlobal public health burdenMajor public health concernEpidemiology of traumaPublic health burdenPublic health approachPublic health issuePublic health concernDeterminants of diseaseHealth burdenHigh prevalenceEpidemiologic studiesGlobal prevalenceEpidemiological studiesHealth problemsTrauma exposureHealth approachHealth concernPTE exposureHealth issuesDisordersTraumaCross-study comparisonsPublic healthEpidemiologyReduced social contact and attachment insecurity as predictors of loneliness during COVID-19: A two-month experience sampling study
Lewis K, Roche M, Brown F, Tillman J. Reduced social contact and attachment insecurity as predictors of loneliness during COVID-19: A two-month experience sampling study. Personality And Individual Differences 2022, 195: 111672. PMID: 35475241, PMCID: PMC9023336, DOI: 10.1016/j.paid.2022.111672.Peer-Reviewed Original ResearchExperience sampling periodDaily social contactsAttachment styleSocial contactPsychological distressExperience Sampling StudyDaily social behaviorReduced social contactGeneral adult samplesAttachment insecurityPredictors of lonelinessPersonality factorsAttachment traitsAdult samplesPersonality characteristicsSocial behaviorMental healthFuture empirical studiesLonelinessClinical interventionsDistressSampling studyCOVID-19 pandemicMajor public health concernGreater experience
2021
Top Priorities for Cerebroprotective Studies—A Paradigm Shift
Lyden P, Buchan A, Boltze J, Fisher M, Ansari S, Broderick J, Campbell B, Chaisinanunkul N, Chen C, Grotta J, Haddad W, Hareedy R, Hill M, Houser G, Jadhav A, Khatri P, Kimberly W, Koenig J, Korinek W, Landen J, Lansberg M, Latour L, Liebeskind D, Liston T, Lynch J, McGonigle J, Mistry E, Mocco J, Pryor K, Saver J, Savitz S, Sheth K, Solberg Y, Vagal A, Venkatasubramanian C, Ziogas N. Top Priorities for Cerebroprotective Studies—A Paradigm Shift. Stroke 2021, 52: 3063-3071. PMID: 34289707, PMCID: PMC8384700, DOI: 10.1161/strokeaha.121.034947.Peer-Reviewed Original ResearchConceptsComprehensive preclinical assessmentPreclinical assessmentNeurovascular unitMajor public health concernSalvageable brain tissueStroke symptom onsetIschemic stroke treatmentBlood-brain barrierConsensus-based recommendationsPharmacokinetics/pharmacodynamicsClinical trial designPaucity of evidencePublic health concernDifferent brain regionsMechanism of actionCerebroprotective agentTerm neuroprotectionIschemic strokeSymptom onsetStroke treatmentClinical outcomesComorbid conditionsCore injuryClinical trialsStroke modelHypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research
Chandler P, Clark C, Zhou G, Noel N, Achilike C, Mendez L, Ramirez A, Loperena-Cortes R, Mayo K, Cohn E, Ohno-Machado L, Boerwinkle E, Cicek M, Qian J, Schully S, Ratsimbazafy F, Mockrin S, Gebo K, Dedier J, Murphy S, Smoller J, Karlson E. Hypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research. Scientific Reports 2021, 11: 12849. PMID: 34158555, PMCID: PMC8219813, DOI: 10.1038/s41598-021-92143-w.Peer-Reviewed Original ResearchConceptsPrevalence of hypertensionHTN prevalenceUs Research ProgramMajor public health concernBlood pressure medicationsPopulation-based studyNutrition Examination SurveyBlood pressure measurementsPopulation-based surveyEHR dataPatient measurementsPublic health concernAntihypertensive medicationsEHR cohortHTN medicationsHypertension prevalenceCrude prevalenceHypertension casesHypertension treatmentExamination SurveyNational HealthHypertensionBilling codesMedicationsCohort
2019
Prevalence and associated factors of childhood overweight/obesity among primary school children in urban Nepal
Karki A, Shrestha A, Subedi N. Prevalence and associated factors of childhood overweight/obesity among primary school children in urban Nepal. BMC Public Health 2019, 19: 1055. PMID: 31387571, PMCID: PMC6685156, DOI: 10.1186/s12889-019-7406-9.Peer-Reviewed Original ResearchConceptsChildhood overweight/obesityOverweight/obesityOverweight/obeseChildren of mothersTwo-stage cluster random samplingMale childrenMultivariate logistic regression analysisPrimary school childrenMajor public health concernMethodsA cross-sectional surveyLogistic regression analysisAdverse health consequencesUrban primary school childrenEnergy-dense foodsPublic health concernStructured self-administered questionnaireCross-sectional surveyJunk food consumptionChi-square testSchool childrenSPSS version 21Self-administered questionnaireChildhood overweightParents of childrenAssociated Factors
2016
An overview of alcohol and tobacco/nicotine interactions in the human laboratory
Verplaetse TL, McKee SA. An overview of alcohol and tobacco/nicotine interactions in the human laboratory. The American Journal Of Drug And Alcohol Abuse 2016, 43: 186-196. PMID: 27439453, PMCID: PMC5588903, DOI: 10.1080/00952990.2016.1189927.Peer-Reviewed Original ResearchConceptsAlcohol-tobacco interactionsNicotine interactionsHuman laboratorySubjective responsesBlood alcohol curveDrinking cuesAlcohol use disorderOverview of alcoholNicotine deprivationSelf-administration behaviorDrugs of abuseAlcohol cravingReciprocal influenceAlcohol curveAlcohol influenceSubjective effectsUse disordersTobacco/nicotineNicotine administrationTobacco useInteractive effectsCravingMajor public health concernPublic health concernDrinkersLeptospira in breast tissue and milk of urban Norway rats (Rattus norvegicus)
DE OLIVEIRA D, FIGUEIRA CP, ZHAN L, PERTILE AC, PEDRA GG, GUSMÃO IM, WUNDER EA, RODRIGUES G, RAMOS EA, KO AI, CHILDS JE, REIS MG, COSTA F. Leptospira in breast tissue and milk of urban Norway rats (Rattus norvegicus). Epidemiology And Infection 2016, 144: 2420-2429. PMID: 27019024, PMCID: PMC5437553, DOI: 10.1017/s0950268816000637.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionBreast tissuePresence of leptospiresNorway ratsMajor public health concernMilk-borne transmissionMajor pathological changesReal-time polymerase chain reactionPublic health concernQuantitative real-time polymerase chain reactionPathogenic Leptospira sppBreast tissue samplesChronic carriagePathological changesLactating ratsRatsHealth concernImmunofluorescence assaysLeptospira sppGenus LeptospiraTissue samplesUrban slumsChain reactionLeptospiresLeptospiraTelestroke—the promise and the challenge. Part two—expansion and horizons
Akbik F, Hirsch J, Chandra R, Frei D, Patel A, Rabinov J, Rost N, Schwamm L, Leslie-Mazwi T. Telestroke—the promise and the challenge. Part two—expansion and horizons. Journal Of NeuroInterventional Surgery 2016, 9: 361. PMID: 26984867, DOI: 10.1136/neurintsurg-2016-012340.Peer-Reviewed Original ResearchConceptsSpecialist careMajor public health concernAcute ischemic strokeTime-sensitive therapiesExamination of patientsUse of telemedicinePublic health concernNovel therapeutic platformIntravenous thrombolysisStroke preventionEndovascular thrombectomyIschemic strokeStroke presentationStroke expertiseTreatment benefitVideo consultationsTreatment ratesHealth concernTelestrokeCarePotential roleStrokeSensitive therapyTherapeutic platformThrombectomyTelestroke—the promise and the challenge. Part one: growth and current practice
Akbik F, Hirsch J, Chandra R, Frei D, Patel A, Rabinov J, Rost N, Schwamm L, Leslie-Mazwi T. Telestroke—the promise and the challenge. Part one: growth and current practice. Journal Of NeuroInterventional Surgery 2016, 9: 357. PMID: 26984868, DOI: 10.1136/neurintsurg-2016-012291.Peer-Reviewed Original ResearchConceptsSpecialist careMajor public health concernAcute ischemic strokeLarge vessel occlusionManagement of patientsTime-sensitive therapiesExamination of patientsUse of telemedicinePublic health concernIntravenous thrombolysisEndovascular thrombectomyIschemic strokeStroke presentationStroke expertiseVessel occlusionTreatment benefitVideo consultationsTreatment ratesHealth concernTelestrokeCurrent practicePatientsStrokeSensitive therapyCareNature and determinants of suicidal ideation among U.S. veterans: Results from the national health and resilience in veterans study
Smith NB, Mota N, Tsai J, Monteith L, Harpaz-Rotem I, Southwick SM, Pietrzak RH. Nature and determinants of suicidal ideation among U.S. veterans: Results from the national health and resilience in veterans study. Journal Of Affective Disorders 2016, 197: 66-73. PMID: 26970267, DOI: 10.1016/j.jad.2016.02.069.Peer-Reviewed Original ResearchConceptsChronic suicidal ideationPhysical health difficultiesSuicidal ideationU.S. veteransProtective psychosocial characteristicsNational HealthPsychosocial characteristicsHealth difficultiesSI onsetMajor public health concernProspective cohort studyPublic health concernSubstance abuse historyWave 1Majority of veteransU.S. military veteransCohort studyProtective correlatesTwo-week timeframePsychiatric distressVeterans StudySociodemographic characteristicsSuicidal thoughtsHealth concernTreatment effortsEffectiveness of Residential Acaricides to Prevent Lyme and Other Tick-borne Diseases in Humans
Hinckley A, Meek J, Ray J, Niesobecki S, Connally N, Feldman K, Jones E, Backenson P, White J, Lukacik G, Kay A, Miranda W, Mead P. Effectiveness of Residential Acaricides to Prevent Lyme and Other Tick-borne Diseases in Humans. The Journal Of Infectious Diseases 2016, 214: 182-188. PMID: 26740276, PMCID: PMC10874626, DOI: 10.1093/infdis/jiv775.Peer-Reviewed Original ResearchConceptsTick-borne diseasesHuman-tick encountersMajor public health concernPlacebo-controlled trialMedical record reviewHuman tick-borne diseasesReports of illnessPublic health concernPublic health authoritiesTick-borne diseaseRecord reviewTick biteTick exposureTreatment groupsHealth authoritiesDiseaseHealth concernQuesting ticksHuman outcomesTicksUse of acaricidesIllnessIncidenceTrialsWeeks
2015
VA Patients With High Numbers of Opioid Prescriptions
Petrakis I, Sofuoglu M, Rosenheck R. VA Patients With High Numbers of Opioid Prescriptions. Addictive Disorders & Their Treatment 2015, 14: 167-175. DOI: 10.1097/adt.0000000000000058.Peer-Reviewed Original ResearchHigh opioid useOpioid usePrescription opioid useOpioid prescriptionsOpioid groupOutpatient visitsHigher prescription opioid useVeterans Health Administration usersVeterans Health Administration patientsLogistic regressionDrug abuseMajor public health concernAntidepressant medication prescriptionMedical outpatient visitsOpioid prescription useEmergency room visitsComorbid drug useDrug use disordersForm of painPsychotropic medication usagePublic health concernConcomitant antidepressantsAntidepressant prescriptionsPsychotropic prescriptionsMedical illnessA novel approach to training students in delivering evidence-based obesity treatment.
Brown J, Lydecker JA, Turner T, Knackstedt RW, O'Neil PM. A novel approach to training students in delivering evidence-based obesity treatment. Family Medicine 2015, 47: 378-82. PMID: 25905881.Peer-Reviewed Original ResearchConceptsHealth care studentsCare studentsEvidence-based obesity treatmentInterprofessional health care studentsMajor public health concernLow-income overweightWeight management professionalsWeight management interventionsService-learning componentService-learning opportunitiesService-learning programEvidence-based treatmentsHealth care providersPublic health concernSerious health consequencesPatient weightObesity treatmentAddress obesityStudents' deliveryExperiential learningCare providersTraining studentsEducational curriculumDidactic instructionObesityThe role of gut microbiota in the development of type 1, type 2 diabetes mellitus and obesity
Tai N, Wong FS, Wen L. The role of gut microbiota in the development of type 1, type 2 diabetes mellitus and obesity. Reviews In Endocrine And Metabolic Disorders 2015, 16: 55-65. PMID: 25619480, PMCID: PMC4348024, DOI: 10.1007/s11154-015-9309-0.Peer-Reviewed Original ResearchConceptsGut microbiotaAutoimmune type 1 diabetesType 2 diabetes mellitusInsulin-resistant type 2 diabetesMajor public health concernAltered gut microbiotaDevelopment of T1DType 2 diabetesType 1 diabetesGut microbiota compositionPublic health concernDiabetes mellitusPersistent hyperglycemiaMetabolic disordersRodent modelsMicrobiota compositionType 1ObesityDiabetesHealth concernPotential mechanismsMicrobiotaT2DT1DDisease developmentOsteoporosis and Hip Fractures
Olgun D, Gianakos A, Jo J, Galmer L, Lane J. Osteoporosis and Hip Fractures. 2015, 141-158. DOI: 10.1007/978-3-319-19905-4_8.Peer-Reviewed Original ResearchHip fractureFragility fracturesFragility fracture risk factorsOsteoporosis-related fragility fracturesMajor public health concernFracture risk factorsFracture liaison serviceMajority of patientsOsteoporotic fragility fracturesResidual functional impairmentOsteoporotic hip fracturesPublic health concernOsteoporosis managementPatient mortalityRisk factorsPatient outcomesPharmacological strategiesFunctional impairmentLiaison serviceSubsequent fracturesGreater riskHealth concernHealthcare expendituresOsteoporosisBone evaluation
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