2024
Same-Day Primary Care Referral Versus Usual Care for Patients With Elevated Blood Pressures Seen in a Preoperative Clinic
Butler S, Holt N, Dai F, Quick C, Kravetz J, Perrino A, Schonberger R. Same-Day Primary Care Referral Versus Usual Care for Patients With Elevated Blood Pressures Seen in a Preoperative Clinic. Cureus 2024, 16: e58401. PMID: 38756290, PMCID: PMC11098054, DOI: 10.7759/cureus.58401.Peer-Reviewed Original ResearchPrimary care referralsPrimary care groupsCare referralUsual careCare groupPreoperative clinicQuality improvementCare coordination effortsLong-term health outcomesPrimary care visitsPrimary care appointmentsCohort of US veteransMonths post-interventionSame-day referralElectronic health recordsBlood pressureSurgical care episodesHypertension treatmentProspective QI projectPreoperative evaluation clinicImprove BP controlQI projectCare appointmentsPreoperative clinic visitPrimary care
2022
Primary care clinicians’ use of deprescribing recommendations: A mixed-methods study
Mecca MC, Zenoni M, Fried TR. Primary care clinicians’ use of deprescribing recommendations: A mixed-methods study. Patient Education And Counseling 2022, 105: 2715-2720. PMID: 35523638, DOI: 10.1016/j.pec.2022.04.013.Peer-Reviewed Original ResearchConceptsMedication-related communicationPrimary care cliniciansMedication reconciliationCare cliniciansThorough medication reconciliationClinical decision support toolChronic disease managementAdherence discussionsMedication appropriatenessHypertension medicationsInappropriate medicationsMedication changesIntervention cliniciansHypertension treatmentPrimary careIntervention groupClinician practiceMedicationsIndividualized reportsCliniciansDeintensificationDisease managementMixed-method studyFeedback reportsReportProceedings From a National Heart, Lung, and Blood Institute and the Centers for Disease Control and Prevention Workshop to Control Hypertension
Commodore-Mensah Y, Loustalot F, Himmelfarb CD, Desvigne-Nickens P, Sachdev V, Bibbins-Domingo K, Clauser SB, Cohen DJ, Egan BM, Fendrick AM, Ferdinand KC, Goodman C, Graham GN, Jaffe MG, Krumholz HM, Levy PD, Mays GP, McNellis R, Muntner P, Ogedegbe G, Milani RV, Polgreen LA, Reisman L, Sanchez EJ, Sperling LS, Wall HK, Whitten L, Wright JT, Wright JS, Fine LJ. Proceedings From a National Heart, Lung, and Blood Institute and the Centers for Disease Control and Prevention Workshop to Control Hypertension. American Journal Of Hypertension 2022, 35: 232-243. PMID: 35259237, PMCID: PMC8903890, DOI: 10.1093/ajh/hpab182.Peer-Reviewed Original ResearchConceptsHypertension controlBlood pressureHypertension treatmentBlood InstituteNational HeartSelf-measured BP monitoringDisease controlCommunity-clinical linkagesModifiable risk factorsMore cardiovascular eventsAge-adjusted proportionSurgeon General's CallTeam-based careHigh-quality health carePublic health messagingCardiovascular eventsStroke preventionControl hypertensionBP monitoringHeart diseaseRisk factorsUS adultsClinical supportHealth messagingSocial determinants
2021
Feasibility of a randomized hypertension screening initiative in the perioperative setting
Diaz SI, Yan L, Dai F, Zhou B, Burg MM, Schonberger RB. Feasibility of a randomized hypertension screening initiative in the perioperative setting. Perioperative Medicine 2021, 10: 39. PMID: 34802471, PMCID: PMC8607702, DOI: 10.1186/s13741-021-00210-7.Peer-Reviewed Original ResearchHBPM groupHome BP monitorPreoperative clinicCounseling groupBlood pressure interventionsBlood pressure trialConclusionsThis feasibility studyElevated blood pressurePrimary care providersPreadmission visitHypertension medicationsPressure trialBlood pressureHypertension treatmentPressure interventionOutcome ascertainmentTelephone followPrimary careTesting clinicPerioperative settingBP monitorCare providersEducational brochurePatientsBaseline rateHypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research
Chandler P, Clark C, Zhou G, Noel N, Achilike C, Mendez L, Ramirez A, Loperena-Cortes R, Mayo K, Cohn E, Ohno-Machado L, Boerwinkle E, Cicek M, Qian J, Schully S, Ratsimbazafy F, Mockrin S, Gebo K, Dedier J, Murphy S, Smoller J, Karlson E. Hypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research. Scientific Reports 2021, 11: 12849. PMID: 34158555, PMCID: PMC8219813, DOI: 10.1038/s41598-021-92143-w.Peer-Reviewed Original ResearchConceptsPrevalence of hypertensionHTN prevalenceUs Research ProgramMajor public health concernBlood pressure medicationsPopulation-based studyNutrition Examination SurveyBlood pressure measurementsPopulation-based surveyEHR dataPatient measurementsPublic health concernAntihypertensive medicationsEHR cohortHTN medicationsHypertension prevalenceCrude prevalenceHypertension casesHypertension treatmentExamination SurveyNational HealthHypertensionBilling codesMedicationsCohort
2020
Principles of Large-scale Evidence Generation and Evaluation across a Network of Databases (LEGEND)
Schuemie MJ, Ryan PB, Pratt N, Chen R, You SC, Krumholz HM, Madigan D, Hripcsak G, Suchard MA. Principles of Large-scale Evidence Generation and Evaluation across a Network of Databases (LEGEND). Journal Of The American Medical Informatics Association 2020, 27: 1331-1337. PMID: 32909033, PMCID: PMC7481029, DOI: 10.1093/jamia/ocaa103.Peer-Reviewed Original ResearchConceptsNetwork of databasesLarge-scale Evidence GenerationObservational Health Data SciencesObservational health care databasesHealth Data SciencesHealth care dataElectronic health recordsData sciencePublication biasPatient-level informationGeneric overviewHealth recordsMethods addressAforementioned concernsHealth care databasesAnalytic codeNetworkNew paradigmSuch dataHackingEvidence generationDissemination of evidenceHypertension treatmentResidual confoundingAdministrative claimsEvaluation of Transcatheter Alcohol-Mediated Perivascular Renal Denervation to Treat Resistant Hypertension
Janas A, Król M, Hochuł M, Jochymczyk M, Hayward-Costa C, Parise H, Haratani N, Fischell T, Wojakowski W. Evaluation of Transcatheter Alcohol-Mediated Perivascular Renal Denervation to Treat Resistant Hypertension. Journal Of Clinical Medicine 2020, 9: 1881. PMID: 32560164, PMCID: PMC7356226, DOI: 10.3390/jcm9061881.Peer-Reviewed Original ResearchAmbulatory blood pressure monitoringRenal denervationResistant hypertensionOffice BPCatheter-based renal denervationBlood pressure monitoringRenal artery anatomyHypothesis-generating studyContrast computer tomographyAnti-hypertension drugsNephrologist consultationResistant HTNAdult patientsSympathetic nervesSystolic pressureHypertension treatmentRenal arteryArtery anatomyAdventitial spaceMean decreasePressure monitoringPatientsDenervationHypertensionVariable success
2019
Increasing the Precision of Hypertension Treatment Through Personalized Trials: a Pilot Study
Kronish IM, Cheung YK, Shimbo D, Julian J, Gallagher B, Parsons F, Davidson KW. Increasing the Precision of Hypertension Treatment Through Personalized Trials: a Pilot Study. Journal Of General Internal Medicine 2019, 34: 839-845. PMID: 30859504, PMCID: PMC6544735, DOI: 10.1007/s11606-019-04831-z.Peer-Reviewed Original ResearchConceptsBP medicationsPersonalized trialsBP monitoringSide effectsRenin-angiotensin system-blocking agentsCombination of thiazideAmbulatory BP monitoringHome BP monitoringWhite coat hypertensionProportion of patientsBlood pressure medicationsHome BP devicesStudy cliniciansBP loweringHypertensive patientsTEN patientsBP responseHypertension treatmentMedication preferencePatient preferencesIndividual patientsMedicationsPatientsPilot studyTrials
2018
Barriers and facilitators to treatment among patients with newly diagnosed hypertension in Nepal
Shrestha S, Shrestha A, Koju RP, LoGerfo JP, Karmacharya BM, Sotoodehnia N, Fitzpatrick AL. Barriers and facilitators to treatment among patients with newly diagnosed hypertension in Nepal. Heart Asia 2018, 10: e011047. PMID: 30233660, PMCID: PMC6135456, DOI: 10.1136/heartasia-2018-011047.Peer-Reviewed Original ResearchDhulikhel Heart StudyLow perceived seriousnessAbsence of symptomsAppropriate health interventionsFamily supportDhulikhel HospitalObservational cohortHypertension managementHypertension treatmentHypertensionThematic framework methodHeart StudyCommunity surveillanceHealth interventionsPatientsAudiotaped discussionsDiseaseFear of consequencesTreatmentFramework methodFocus group discussionsBehavior changePerceived SeriousnessQualitative studyMajor barrierComparison of Prevalence, Awareness, Treatment, and Control of Cardiovascular Risk Factors in China and the United States
Lu Y, Wang P, Zhou T, Lu J, Spatz ES, Nasir K, Jiang L, Krumholz HM. Comparison of Prevalence, Awareness, Treatment, and Control of Cardiovascular Risk Factors in China and the United States. Journal Of The American Heart Association 2018, 7: e007462. PMID: 29374046, PMCID: PMC5850247, DOI: 10.1161/jaha.117.007462.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntihypertensive AgentsAttitude of Health PersonnelBlood GlucoseBlood PressureBody Mass IndexCardiovascular DiseasesChinaDiabetes MellitusDyslipidemiasFemaleHealth Knowledge, Attitudes, PracticeHealth Status DisparitiesHumansHypertensionHypolipidemic AgentsLipidsLongitudinal StudiesMaleMiddle AgedNutrition SurveysObesityPractice Patterns, Physicians'PrevalencePrognosisRisk AssessmentRisk FactorsTime FactorsUnited StatesWaist CircumferenceConceptsHigher stroke prevalenceCardiovascular risk factorsHigh-sensitivity C-reactive proteinBody mass indexC-reactive proteinRisk factorsBlood pressureWaist circumferenceMass indexStroke prevalenceCardiovascular risk factor profileHigher mean blood pressureControl of hypertensionMean blood pressureBlood pressure levelsRisk factor profileComparison of prevalenceRepresentative population sampleLower ratesDyslipidemia awarenessSevere hypertensionHemoglobin A1cHypertension treatmentControl ratePlasma glucose
2014
Novel Molecules
Vukelic V, Orias M. Novel Molecules. Clinical Hypertension And Vascular Diseases 2014, 47-55. DOI: 10.1007/978-1-4939-1982-6_5.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAngiotensin II type 2 receptor agonistType 2 receptor agonistBlood pressure controlEnd-organ damageEndothelin receptor antagonistsAldosterone synthase inhibitorsNew therapeutic approachesSoluble epoxide hydrolase inhibitorsSoluble guanylyl cyclaseEpoxide hydrolase inhibitorAldosterone axisHypertension treatmentVasopeptidase inhibitorReceptor antagonistReceptor agonistRecombinant renalaseTherapeutic approachesNew agentsSynthase inhibitorAnimal modelsRenin inhibitorsPressure controlGuanylyl cyclaseAdverse effectsHydrolase inhibitorsOptimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial
Vedanthan R, Kamano JH, Naanyu V, Delong AK, Were MC, Finkelstein EA, Menya D, Akwanalo CO, Bloomfield GS, Binanay CA, Velazquez EJ, Hogan JW, Horowitz CR, Inui TS, Kimaiyo S, Fuster V. Optimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial. Trials 2014, 15: 143. PMID: 24767476, PMCID: PMC4113229, DOI: 10.1186/1745-6215-15-143.Peer-Reviewed Original ResearchMeSH KeywordsBlack PeopleBlood PressureCell PhoneClinical ProtocolsCommunicationCommunity Health ServicesCommunity Health WorkersCost-Benefit AnalysisHealth BehaviorHealth Care CostsHealth Knowledge, Attitudes, PracticeHumansHypertensionKenyaMotivational InterviewingPatient CompliancePatientsProfessional-Patient RelationsResearch DesignRural Health ServicesTime FactorsTreatment OutcomeConceptsCommunity health workersHypertension careBlood pressureHealth workersHypertensive individualsMethods/designThis studyCo-primary outcome measuresNon-communicable disease managementHypertension care programDisability-adjusted life yearsSystolic blood pressureOne-year changeHealth Belief ModelCost-effectiveness analysisUsual careMiddle-income countriesHypertension managementHypertension treatmentControl rateRisk factorsOutcome measuresDesignThis studyBehavioral communication strategyCare programLife yearsNurse Management of Hypertension in Rural Western Kenya: Implementation Research to Optimize Delivery
Vedanthan R, Kamano JH, Horowitz CR, Ascheim D, Velazquez EJ, Kimaiyo S, Fuster V. Nurse Management of Hypertension in Rural Western Kenya: Implementation Research to Optimize Delivery. Annals Of Global Health 2014, 80: 5-12. PMID: 24751560, PMCID: PMC4036099, DOI: 10.1016/j.aogh.2013.12.002.Peer-Reviewed Original ResearchConceptsRural western KenyaNurse managementBlood pressureNoncommunicable disease managementSystolic blood pressurePrimary outcome measureLong-term treatmentWestern KenyaHypertensive patientsHypertensive individualsMiddle-income countriesHypertension managementHypertension treatmentControl rateRisk factorsHypertensionOutcome measuresOptimize deliveryFull-time equivalentsEffectiveness of strategiesImplementation researchNursesDisease managementFeasibility testingRecord-keeping tool
2012
Effects of body size and hypertension treatments on cardiovascular event rates: subanalysis of the ACCOMPLISH randomised controlled trial
Weber MA, Jamerson K, Bakris GL, Weir MR, Zappe D, Zhang Y, Dahlof B, Velazquez EJ, Pitt B. Effects of body size and hypertension treatments on cardiovascular event rates: subanalysis of the ACCOMPLISH randomised controlled trial. The Lancet 2012, 381: 537-545. PMID: 23219284, DOI: 10.1016/s0140-6736(12)61343-9.Peer-Reviewed Original ResearchConceptsCardiovascular event ratesBody mass indexNormal weightPrimary endpointObese patientsEvent ratesCardiovascular outcomesCardiovascular protectionHypertension treatmentObese individualsHigh-risk hypertensive patientsHigher cardiovascular event ratesNon-fatal myocardial infarctionAmlodipine-based therapyAvoiding Cardiovascular EventsPatient’s cardiovascular outcomeSuperior cardiovascular protectionSystolic Hypertension (ACCOMPLISH) trialPrimary event rateSingle-pill combinationPrevious clinical trialsNormal weight categoryCardiovascular deathCardiovascular eventsHypertension trialsObese Schizophrenia Spectrum Patients Have Significantly Higher 10-Year General Cardiovascular Risk and Vascular Ages than Obese Individuals without Severe Mental Illness
Ratliff JC, Palmese LB, Reutenauer EL, Srihari VH, Tek C. Obese Schizophrenia Spectrum Patients Have Significantly Higher 10-Year General Cardiovascular Risk and Vascular Ages than Obese Individuals without Severe Mental Illness. Journal Of The Academy Of Consultation-Liaison Psychiatry 2012, 54: 67-73. PMID: 22664309, PMCID: PMC3435456, DOI: 10.1016/j.psym.2012.03.001.Peer-Reviewed Original ResearchConceptsSevere mental illnessGeneral CVD riskSchizophrenia spectrum patientsVascular ageCVD riskSpectrum patientsNHANES participantsMetabolic riskMental illnessGeneral cardiovascular riskMean vascular ageSystolic blood pressureCardiovascular disease mortalityPrimary care cliniciansHDL cholesterol levelsNutrition Examination SurveyCVD eventsCardiovascular riskObese controlsObese patientsBlood pressureCare cliniciansHypertension treatmentSmoking statusExamination Survey
2005
Cross-Sectional Association of Kidney Function with Valvular and Annular Calcification: The Framingham Heart Study
Fox C, Larson M, Vasan R, Guo C, Parise H, Levy D, Leip E, O’Donnell C, D’Agostino R, Benjamin E. Cross-Sectional Association of Kidney Function with Valvular and Annular Calcification: The Framingham Heart Study. Journal Of The American Society Of Nephrology 2005, 17: 521-527. PMID: 16382018, DOI: 10.1681/asn.2005060627.Peer-Reviewed Original ResearchConceptsMitral annular calcificationAortic annular calcificationAnnular calcificationValvular calcificationKidney diseaseAortic sclerosisKidney functionPresence of MACTotal/HDL cholesterolVascular risk factor burdenRenal Disease Study equationEnd-stage kidney diseaseRisk factor burdenCardiovascular risk factorsCardiovascular disease eventsChronic kidney diseaseEarly kidney diseaseBody mass indexOnset of ESRDFramingham Offspring StudyTwo-dimensional echocardiographyFramingham Heart StudyDiastolic BPHDL cholesterolHypertension treatment
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