2024
Racial and Ethnic Disparities in the Prescribing of Pain Medication in US Primary Care Settings, 1999–2019: Where Are We Now?
Thompson T, Stathi S, Shin J, Carvalho A, Solmi M, Liang C. Racial and Ethnic Disparities in the Prescribing of Pain Medication in US Primary Care Settings, 1999–2019: Where Are We Now? Journal Of General Internal Medicine 2024, 39: 1597-1605. PMID: 38302811, PMCID: PMC11254888, DOI: 10.1007/s11606-024-08638-5.Peer-Reviewed Original ResearchConceptsPrimary care physiciansPrimary care settingCare physiciansEthnic disparitiesCare settingsUS primary care settingsUS primary care physiciansPain treatmentNational Ambulatory Medical Care SurveyPain medicationCross-sectional probability sampleReduce healthcare inequalitiesWhite patientsPopulation-weighted estimatesNarrowing of disparitiesCubic spline regressionAmerican-Indian/Alaska-NativeNon-opioid analgesicsEquitable healthcarePrimary careHealthcare inequalitiesCare SurveyNon-Hispanic/LatinoHispanic/Latino patientsPotential confounders
2023
Trends in Racial Inequalities in the Administration of Opioid and Non-opioid Pain Medication in US Emergency Departments Across 1999–2020
Thompson T, Stathi S, Buckley F, Shin J, Liang C. Trends in Racial Inequalities in the Administration of Opioid and Non-opioid Pain Medication in US Emergency Departments Across 1999–2020. Journal Of General Internal Medicine 2023, 39: 214-221. PMID: 37698724, PMCID: PMC10853122, DOI: 10.1007/s11606-023-08401-2.Peer-Reviewed Original ResearchConceptsUS emergency departmentsEmergency departmentRacial disparitiesPain medicationNon-opioid analgesicsWhite patientsNational Hospital Ambulatory Medical Care SurveyReceipt of pain medicationMagnitude of racial disparitiesCross-sectional probability samplePain treatmentBlack patientsPrescribed pain medicationPopulation-weighted estimatesRelative risk regressionSample of visitsShort-stay hospitalsNon-opioid pain medicationsSeverity of painEquitable healthcareCare SurveyED visitsAdministration of opioidsInsurance statusPotential confoundersDeveloping non-opioid therapeutics to alleviate pain among persons with opioid use disorder: a review of the human evidence
Oliveira D, Fontenele R, Weleff J, Sofuoglu M, De Aquino J. Developing non-opioid therapeutics to alleviate pain among persons with opioid use disorder: a review of the human evidence. International Review Of Psychiatry 2023, 35: 377-396. PMID: 38299655, PMCID: PMC10835074, DOI: 10.1080/09540261.2023.2229430.Peer-Reviewed Original ResearchOpioid agonist therapyOpioid use disorderNon-opioid analgesicsUse disordersNon-opioid analgesic therapyAlpha-2 adrenergic agonistsMajor public health concernGlial activation inhibitorNon-opioid therapeuticsNovel analgesic strategiesPotential of cannabinoidsPrior opioid exposureOpioid-dependent individualsOpioid-dependent populationsAbuse liability assessmentPublic health concernAnalgesic strategiesAgonist therapyAnalgesic therapyOpioid exposureOUD treatmentPharmacokinetic interactionsGABAergic drugsSignificant morbidityPain types
2022
Enhanced Recovery After Surgery: Opioid Sparing Strategies After Discharge: A Review
Rajput K, Shergill S, Chow RM, Vadivelu N, Kaye AD. Enhanced Recovery After Surgery: Opioid Sparing Strategies After Discharge: A Review. Current Pain And Headache Reports 2022, 26: 93-102. PMID: 35072920, DOI: 10.1007/s11916-022-01009-x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid usePersistent post-surgical painNon-opioid strategiesNon-opioid therapiesOpioid-sparing strategiesOverprescribing of opioidsPostoperative pain scoresMultimodal analgesic approachPost-surgical painSide effect profileNon-opioid analgesicsRecent FindingsSeveral studiesERAS protocolOpioid protocolAnalgesic approachBreakthrough painHospital stayMultimodal analgesiaPain scoresAcute painOral ketaminePostoperative periodEffect profilePatient recoveryGood quality research
2021
Acute Pain Management of Chronic Pain Patients in Ambulatory Surgery Centers
Rajput K, Vadivelu N. Acute Pain Management of Chronic Pain Patients in Ambulatory Surgery Centers. Current Pain And Headache Reports 2021, 25: 1. PMID: 33443656, DOI: 10.1007/s11916-020-00922-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPerioperative pain managementAmbulatory surgery centersNon-opioid analgesicsPain managementSurgery centersIntrathecal pain pumpOpioid-tolerant patientsPostoperative opioid requirementsAcute pain managementChronic opioid useProportion of patientsSubset of patientsChronic pain patientsSame-day admission patientsSpinal cord stimulatorPurpose of ReviewWithOpioid requirementsPostoperative opioidsMalignant painMultimodal analgesiaPerioperative painOpioid toleranceOpioid usePain specialistsPain patients
2018
Undertreated pain: Trends over time for older adults with and without cancer.
Presley C, Kapo J, Wang S, Canavan M, Sheinfeld E, Feder S, Kent E, Davidoff A. Undertreated pain: Trends over time for older adults with and without cancer. Journal Of Clinical Oncology 2018, 36: 15-15. DOI: 10.1200/jco.2018.36.30_suppl.15.Peer-Reviewed Original ResearchSevere pain interferencePain interferenceOlder adultsPain managementPain-related activity limitationsModerate pain interferenceSupportive care needsUse of opioidsNon-opioid analgesicsMultivariable logistic regressionPrescription medication usePart D coverageQuality of lifeCalendar year trendsPart D low-income subsidyLow-income subsidyPart D prescriptionsModerate painMedication useSymptom managementCancer historyChronic conditionsActivity limitationsLocal anestheticsCancer status
2015
Daily home opioid use in adults with sickle cell disease: The PiSCES project.
Smith WR, McClish DK, Dahman BA, Levenson JL, Aisiku IP, de A Citero V, Bovbjerg VE, Roberts JD, Penberthy LT, Roseff SD. Daily home opioid use in adults with sickle cell disease: The PiSCES project. Journal Of Opioid Management 2015, 11: 243-53. PMID: 25985809, DOI: 10.5055/jom.2015.0273.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdaptation, PsychologicalAdolescentAdultAnalgesics, OpioidAnemia, Sickle CellAntisickling AgentsCost of IllnessDrug Administration ScheduleDrug Therapy, CombinationFemaleHumansHydroxyureaLongitudinal StudiesMaleMiddle AgedPainPain MeasurementQuality of LifeSelf AdministrationTime FactorsTreatment OutcomeYoung AdultConceptsSickle cell diseaseHome opioid useOpioid usePain daysOpioid usersMean painCell diseasePsychosocial variablesDaily pain diaryMajority of patientsNon-opioid analgesicsSomatic symptom burdenPiSCES projectOpioid prescribingPain frequencyCohort studySymptom burdenPain diaryPain intensityPatient characteristicsPhysical QoLOpioidsPatientsSCD samplesSimilar association
2014
A Partnered Approach to Opioid Management, Guideline Concordant Care and the Stepped Care Model of Pain Management
Dorflinger L, Moore B, Goulet J, Becker W, Heapy AA, Sellinger JJ, Kerns RD. A Partnered Approach to Opioid Management, Guideline Concordant Care and the Stepped Care Model of Pain Management. Journal Of General Internal Medicine 2014, 29: 870-876. PMID: 25355083, PMCID: PMC4239281, DOI: 10.1007/s11606-014-3019-2.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyOpioid risk mitigation strategiesOpioid therapyGuideline-concordant careVeterans Health AdministrationPain managementStepped care modelOpioid managementChronic painPain carePrimary carePractice guidelinesCare modelHigh-dose opioidsKey ResultsThe proportionProportion of patientsNon-opioid analgesicsClinical practice guidelinesCommon presenting problemManagement of veteransPerformance improvement outcomesClinical research teamInteractive educational strategiesFour-year study periodConcordant care
2009
Prescribing discrepancies likely to cause adverse drug events after patient transfer
Boockvar K, Liu S, Goldstein N, Nebeker J, Siu A, Fried T. Prescribing discrepancies likely to cause adverse drug events after patient transfer. BMJ Quality & Safety 2009, 18: 32. PMID: 19204129, PMCID: PMC2728360, DOI: 10.1136/qshc.2007.025957.Peer-Reviewed Original ResearchConceptsAdverse drug eventsPositive predictive valueDrug classesMedication discrepanciesDrug eventsPatient transferObserved positive predictive valueHigh positive predictive valueHigh-risk patientsHigh-risk medicationsNon-opioid analgesicsNursing home patientsSite of careCertain drug classesDrug discrepanciesOpioid analgesicsDrug prescribingMedical recordsNursing homesPatientsPredictive valueCare qualityClinician ratersAnalgesicsTypes of discrepancies
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