2024
Trends in Medicare Reimbursement and Service Volume of Vitreoretinal Procedures: 2000 to 2021
Li E, Adelman R. Trends in Medicare Reimbursement and Service Volume of Vitreoretinal Procedures: 2000 to 2021. Journal Of VitreoRetinal Diseases 2024, 9: 31-36. PMID: 39539838, PMCID: PMC11556364, DOI: 10.1177/24741264241292743.Peer-Reviewed Original ResearchVitreoretinal proceduresStatistically significant decreasePanretinal photocoagulation treatmentInflation-adjusted Medicare reimbursementSignificant decreaseSpearman correlationMedicare Part B National Summary Data FilesScleral bucklingEvaluate time trendsIntravitreal injectionPhotocoagulation treatmentNational reimbursement ratesSpearman correlation coefficientPractice patternsPatient coverageMedicare Physician Fee ScheduleStatistical significancePhysician fee scheduleMedicare reimbursementSignificant declineReimbursement ratesInjectionReimbursement trendsTime trendsIntravitrealIntegrating 4 Methods (In4M) to evaluate physical function in patients with cancer: Results of a comprehensive digital health study.
Thanarajasingam G, Dueck A, Bhatnagar V, Brown A, Cathcart-Rake E, Diamond M, Faust L, Fiero M, Huntington S, Jeffery M, Jones L, Paludo J, Power B, Ross J, Ruddy K, Schellhorn S, Tarver M, Wood W, Gross C, Kluetz P. Integrating 4 Methods (In4M) to evaluate physical function in patients with cancer: Results of a comprehensive digital health study. Journal Of Clinical Oncology 2024, 42: 1564-1564. DOI: 10.1200/jco.2024.42.16_suppl.1564.Peer-Reviewed Original ResearchPhysical functionPF measuresDaily stepsClinically meaningful change scoresAverage daily stepsEvaluate physical functionDigital health studiesMeasures of PFWearable dataHealth StudyWalk testWeekend daysCore outcomeChange scoresPerformance statusTreatment toleranceDetect changesPearson correlationECOG performance statusBreast cancerEvaluate feasibilityCancer trialsSignificant declineData collectionBaseline
2022
HPV type‐specific trends in cervical precancers in the United States, 2008 to 2016
Gargano JW, McClung N, Lewis RM, Park IU, Whitney E, Castilho JL, Pemmaraju M, Niccolai LM, Brackney M, DeBess E, Ehlers S, Bennett NM, Scahill M, Cleveland AA, Querec TD, Unger ER, Markowitz LE, Group H. HPV type‐specific trends in cervical precancers in the United States, 2008 to 2016. International Journal Of Cancer 2022, 152: 137-150. PMID: 35904861, DOI: 10.1002/ijc.34231.Peer-Reviewed Original ResearchConceptsHR-HPV typesAverage annual percent changeCross-sectional population-based dataCases of CIN2Individual HPV typesHuman papillomavirus vaccinationCervical intraepithelial neoplasiaIncidence rate ratiosPopulation-based dataConfidence intervalsAnnual percent changeOlder age groupsSignificant declineHPV vaccinationNonvaccine typesPapillomavirus vaccinationHPV typesVaccine impactIntraepithelial neoplasiaIncidence rateCervical precancerCIN2Percent changeAge groupsType replacementFertility Counseling beyond 40
Mor A, Seifer D. Fertility Counseling beyond 40. 2022, 98-105. DOI: 10.1017/9781009025270.009.Peer-Reviewed Original ResearchRevisiting the Principles of Preservation in an Era of Pandemic Obesity
Langford JT, DiRito JR, Doilicho N, Chickering GR, Stern DA, Ouyang X, Mehal W, Tietjen GT. Revisiting the Principles of Preservation in an Era of Pandemic Obesity. Frontiers In Immunology 2022, 13: 830992. PMID: 35432296, PMCID: PMC9011385, DOI: 10.3389/fimmu.2022.830992.Peer-Reviewed Original ResearchConceptsDeceased donorsOrgan preservationDonor populationIschemia-reperfusion injuryCurrent obesity epidemicHealthy donor populationPandemic obesityObese donorsReperfusion injuryMetabolic dysfunctionObesity epidemicObesitySignificant declineOrgansDonorsPopulationCurrent practiceDysfunctionTransplantInjury
2020
Changes in Population-Level and Institutional-Level Prescribing Habits of Radioiodine Therapy for Papillary Thyroid Cancer
Jacobs D, Breen CT, Pucar D, Holt E, Judson BL, Mehra S. Changes in Population-Level and Institutional-Level Prescribing Habits of Radioiodine Therapy for Papillary Thyroid Cancer. Thyroid 2020, 31: 272-279. PMID: 32811347, DOI: 10.1089/thy.2020.0237.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancerNational Cancer DatabaseThyroid cancerRadioactive iodine therapyNumber of patientsHospital-specific effectsIodine therapyAdvanced diseaseTotal thyroidectomyRadioiodine therapyPrescribing habitsRAI useCancer DatabaseMixed regression modelsPatientsJoinpoint analysisHospitalIndividual hospitalsCancerHospital selectionNational trendsThyroidectomyTherapySignificant declineRegression modelsTemporal trends in opioid prescribing patterns among oncologists in the Medicare population.
Jairam V, Yang D, Pasha S, Soulos P, Gross C, Yu J, Park H. Temporal trends in opioid prescribing patterns among oncologists in the Medicare population. Journal Of Clinical Oncology 2020, 38: 12022-12022. DOI: 10.1200/jco.2020.38.15_suppl.12022.Peer-Reviewed Original ResearchOpioid prescribing ratesOpioid prescribingPrescribing ratesUnited States opioid epidemicNon-cancer populationMultivariable negative binomial regressionFinal study sampleSymptom managementOpioid claimsPatient populationOpioid epidemicMedicare patientsProvider characteristicsMedicare populationPatient countsOncologistsNegative binomial regressionPrescribingPatientsStudy sampleBinomial regressionSignificant declinePopulationStatewide levelTemporal trendsHuman Papillomavirus 16/18–Associated Cervical Lesions: Differences by Area-Based Measures of Race and Poverty
Brackney MM, Gargano JW, Hannagan SE, Meek J, Querec TD, Niccolai LM. Human Papillomavirus 16/18–Associated Cervical Lesions: Differences by Area-Based Measures of Race and Poverty. American Journal Of Preventive Medicine 2020, 58: e149-e157. PMID: 32001053, DOI: 10.1016/j.amepre.2019.12.003.Peer-Reviewed Original ResearchConceptsHuman papillomavirus 16/18Area-based measuresProportion of lesionsCervical lesionsMultivariable logistic regression modelingHuman papillomavirus vaccineLogistic regression modelingPapillomavirus vaccineHuman papillomavirusInsurance statusNew Haven CountyHealth outcomesCensus tract characteristicsSociodemographic characteristicsLesionsIndependent effectsRegression modelingWomenEarly declineSignificant declineEthnicity
2019
962. Trends in Cervical Pre-cancers by Race and Ethnicity During the Human Papillomavirus Vaccine Era, HPV Vaccine Impact Monitoring Project (HPV-IMPACT), United States, 2008–2016
Gargano J, Lewis R, Hunt H, McClung N, Bennett N, Griffin M, Niccolai L, Park I, Powell M, Brackney M, Scahill M, Pemmaraju M, Fink D, Ehlers S, Cleveland A, Unger E, Markowitz L. 962. Trends in Cervical Pre-cancers by Race and Ethnicity During the Human Papillomavirus Vaccine Era, HPV Vaccine Impact Monitoring Project (HPV-IMPACT), United States, 2008–2016. Open Forum Infectious Diseases 2019, 6: s29-s29. PMCID: PMC6809029, DOI: 10.1093/ofid/ofz359.064.Peer-Reviewed Original ResearchAverage annual percentage changeCervical intraepithelial neoplasiaRace/ethnicityVaccine eraYear oldsNH blacksNH whitesHuman papillomavirus vaccine introductionActive population-based surveillanceHPV vaccine eraPopulation-based surveillanceConfidence intervalsAnnual percentage changeSignificant declineScreened womenVaccine impactRace/ethnicity dataCervical cancerIntraepithelial neoplasiaVaccine introductionCIN2Hispanic womenJoinpoint softwareSitu casesAge groupsO17.5 Declining trends in anogenital warts since HPV vaccine introduction in a large urban health system, 2013–2017
Yakely A, Oliviera C, Niccolai L. O17.5 Declining trends in anogenital warts since HPV vaccine introduction in a large urban health system, 2013–2017. Sexually Transmitted Infections 2019, 95: a79. DOI: 10.1136/sextrans-2019-sti.203.Peer-Reviewed Original ResearchIncident anogenital wartsAnogenital wartsHPV vaccineVaccine impactBirth cohortImportant public health priorityLarge urban health systemElectronic medical record dataHPV vaccine impactTrends of HPVHPV vaccine introductionNumber of patientsPublic health priorityMedical record dataSignificant declineProportion of visitsUrban health systemBirth cohort analysisCochran-Armitage testEarlier birth cohortsLater birth cohortsMale vaccinationGenital wartsRoutine vaccinationRoutine recommendation
2018
National trends in Fontan operation and in-hospital outcomes in the USA
Akintoye E, Miranda W, Veldtman G, Connolly H, Egbe A. National trends in Fontan operation and in-hospital outcomes in the USA. Heart 2018, 105: 708-714. PMID: 30377261, DOI: 10.1136/heartjnl-2018-313680.Peer-Reviewed Original ResearchConceptsFontan operationHospital mortalityPostoperative complicationsClinical Modification procedure codesHypoplastic left heart syndromePostoperative cardiac complicationsCongenital heart disease diagnosisNationwide Inpatient SampleAcute care facilitiesLength of stayNumber of patientsDiseases-Ninth RevisionVolume of proceduresSignificant declineNumber of proceduresCardiac complicationsRespiratory complicationsHospital dischargeHospital outcomesPatient demographicsMedian ageHeart syndromeHospitalisation costsPatient populationSignificant changes
2017
Declines in Human Papillomavirus (HPV)–Associated High-Grade Cervical Lesions After Introduction of HPV Vaccines in Connecticut, United States, 2008–2015
Niccolai LM, Meek JI, Brackney M, Hadler JL, Sosa LE, Weinberger DM. Declines in Human Papillomavirus (HPV)–Associated High-Grade Cervical Lesions After Introduction of HPV Vaccines in Connecticut, United States, 2008–2015. Clinical Infectious Diseases 2017, 65: 884-889. PMID: 28520854, DOI: 10.1093/cid/cix455.Peer-Reviewed Original ResearchConceptsCervical cancer screeningCervical lesionsRisk behaviorsHPV vaccinationVaccination coverageHuman papillomavirusCancer screeningBirth cohortHigh-grade cervical lesionsHPV vaccination coverageRates of CIN2Cervical intraepithelial neoplasiaHigh-grade lesionsSexual risk behaviorsSignificant declineHPV vaccineVaccine impactIntraepithelial neoplasiaCervical cancerRisk factorsSurveillance periodSimilar epidemiologyChlamydia trachomatisCohort patternsNegative binomial regression
2016
A critical assessment on kidney allocation systems
Formica RN. A critical assessment on kidney allocation systems. Transplantation Reviews 2016, 31: 61-67. PMID: 27919635, DOI: 10.1016/j.trre.2016.10.002.Peer-Reviewed Original ResearchConceptsKidney allocation systemKidney allocationKidney Donor Profile IndexNew kidney allocation systemDelayed graft functionCold ischemic timeDeceased donor kidneysNumber of transplantsOrgan procurement organizationsGraft functionKidney transplantationIschemic timeDonor kidneysTransplant centersOrgan discard ratesClose monitoringMedical needKidneyProcurement organizationsPatientsTransplantationAllocation systemLife savingSignificant declineProfile indexEnhanced hypoxic tolerance by Seabuckthorn is due to upregulation of HIF-1α and attenuation of ER stress
Jain K, Suryakumar G, Prasad R, Ganju L, Singh S. Enhanced hypoxic tolerance by Seabuckthorn is due to upregulation of HIF-1α and attenuation of ER stress. Journal Of Applied Biomedicine 2016, 14: 71-83. DOI: 10.1016/j.jab.2015.10.001.Peer-Reviewed Original ResearchHIF-1αHypoxic toleranceER stressAnti-inflammatory effectsPro-survival effectsFree radical productionCardioprotective actionCardiac damageHO-1NF-κBHerbal supplementsKey adaptive responseOxidative stressTwo-fold increaseHsp70 levelsAntioxidant potentialProtein carbonylationRadical productionHypoxiaSignificant declineSignaling cascadesAdaptive responseCross talkNovel insightsRedox homeostasis
2014
Impact of centralising acute stroke services in English metropolitan areas on mortality and length of hospital stay: difference-in-differences analysis
Morris S, Hunter R, Ramsay A, Boaden R, McKevitt C, Perry C, Pursani N, Rudd A, Schwamm L, Turner S, Tyrrell P, Wolfe C, Fulop N. Impact of centralising acute stroke services in English metropolitan areas on mortality and length of hospital stay: difference-in-differences analysis. The BMJ 2014, 349: g4757. PMID: 25098169, PMCID: PMC4122734, DOI: 10.1136/bmj.g4757.Peer-Reviewed Original ResearchConceptsAcute stroke servicesAcute stroke careHospital stayHyperacute careStroke servicesStroke careHospital Episode Statistics databaseSymptoms of strokePatient-level dataSignificant declineIschemic strokeHospital admissionStayPatientsAbsolute reductionMortalityStrokeMortality dataCareStatistics databaseMonth periodGreater ManchesterAdmissionDaysRiskNational Trends in Patient Safety for Four Common Conditions, 2005–2011
Wang Y, Eldridge N, Metersky ML, Verzier NR, Meehan TP, Pandolfi MM, Foody JM, Ho SY, Galusha D, Kliman RE, Sonnenfeld N, Krumholz HM, Battles J. National Trends in Patient Safety for Four Common Conditions, 2005–2011. New England Journal Of Medicine 2014, 370: 341-351. PMID: 24450892, PMCID: PMC4042316, DOI: 10.1056/nejmsa1300991.Peer-Reviewed Original ResearchConceptsCongestive heart failureAcute myocardial infarctionMore adverse eventsProportion of patientsAdverse event ratesAdverse eventsHeart failureMyocardial infarctionRate of occurrenceCommon medical conditionsMedical recordsMedicare patientsMedical conditionsPatientsSurgeryInfarctionPneumoniaHospitalizationPatient safetyNational trendsMonitoring System dataSignificant declineFailureProportionRate
2013
National Trends in Heart Failure Hospital Stay Rates, 2001 to 2009
Chen J, Dharmarajan K, Wang Y, Krumholz HM. National Trends in Heart Failure Hospital Stay Rates, 2001 to 2009. Journal Of The American College Of Cardiology 2013, 61: 1078-1088. PMID: 23473413, PMCID: PMC3939721, DOI: 10.1016/j.jacc.2012.11.057.Peer-Reviewed Original ResearchConceptsHospital stay ratesLength of stayHF hospital stayHospital mortalityYears of ageHospital stayPatients 18Stay ratesNational Inpatient Sample dataU.S. hospital dischargesPatients 65 yearsPrimary discharge diagnosisSignificant declineOlder Medicare beneficiariesNational Inpatient SampleBlack menLarge national datasetHospital dischargeOlder patientsPatients 55Younger patientsDischarge diagnosisInpatient SampleMedicare beneficiariesAge 65
2010
Effect of the new legislation and single-embryo transfer policy in Turkey on assisted reproduction outcomes: preliminary results
Kutlu P, Atvar O, Vanlioglu O, Kutlu U, Arici A, Yilmaz S, Yilmaz E, Delikara N, Bener F, Kamar A, Alpak O, Ozekici U. Effect of the new legislation and single-embryo transfer policy in Turkey on assisted reproduction outcomes: preliminary results. Reproductive BioMedicine Online 2010, 22: 208-214. PMID: 21195669, DOI: 10.1016/j.rbmo.2010.10.007.Peer-Reviewed Original ResearchConceptsMultiple pregnancy ratePregnancy rateAge groupsSingle embryo transfer policyOverall populationClinical pregnancy rateSecond treatment cycleAssisted reproduction outcomesYears of ageNumber of embryosDifferent age groupsClinical pregnancyMulticentre studyMultiple pregnanciesReproduction treatmentTreatment cyclesReproduction outcomesOlder agePregnancyOutcomesFurther investigationSignificant declineFurther cyclesAgeGroup
2009
Superordinate identity and intergroup roommate friendship development
West T, Pearson A, Dovidio J, Shelton J, Trail T. Superordinate identity and intergroup roommate friendship development. Journal Of Experimental Social Psychology 2009, 45: 1266-1272. DOI: 10.1016/j.jesp.2009.08.002.Peer-Reviewed Original ResearchCommon ingroup identityIngroup identityMembers of outgroupsIntergroup friendshipsIntergroup commonalitySuperordinate identityFriendship developmentCollege roommatesFeelings of friendshipInitial perceptionsRelationship developmentPositive attitudesPresent researchFriendshipCommon identityDyadsRoommatesCommonalitiesAnxietyIdentityHigh levelsSignificant declinePerceptionFeelingsOutgroup
1994
A decline in HIV-infected needles returned to New Haven's needle exchange program: client shift or needle exchange?
Kaplan EH, Khoshnood K, Heimer R. A decline in HIV-infected needles returned to New Haven's needle exchange program: client shift or needle exchange? American Journal Of Public Health 1994, 84: 1991-4. PMID: 7998644, PMCID: PMC1615375, DOI: 10.2105/ajph.84.12.1991.Peer-Reviewed Original Research
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