2025
Chapter 14 Molecular biology, genetic, and epigenetics of kidney tumor
Kazemi R, Rezaeian A, Deyhimfar R, Taheri D. Chapter 14 Molecular biology, genetic, and epigenetics of kidney tumor. 2025, 209-221. DOI: 10.1016/b978-0-443-27302-5.00003-6.Peer-Reviewed Original ResearchDNA damage repair genesKidney cancer developmentRenal cell carcinomaTumor suppressor genePlanning therapeutic strategiesRenal tumorsUrothelial carcinomaWilms tumorCell carcinomaRenal sarcomaKidney tumorsClinical manifestationsUrological cancersKidney cancerPredisposing genesSuppressor geneTherapeutic strategiesCancer developmentTumorRepair genesCancerCarcinomaKidneyGenetic basisGenetic changes
2024
Epidemiology, treatment and outcomes of primary renal sarcomas in adult patients
Uhlig J, Uhlig A, Deshpande H, Ströbel P, Trojan L, Lotz J, Hurwitz M, Hafez O, Humphrey P, Grünwald V, Kim H. Epidemiology, treatment and outcomes of primary renal sarcomas in adult patients. Scientific Reports 2024, 14: 10038. PMID: 38693188, PMCID: PMC11063157, DOI: 10.1038/s41598-024-60174-8.Peer-Reviewed Original ResearchConceptsAnnual age-adjusted incidence ratesRenal sarcomaOverall survivalAdult patientsSurgical resectionAverage annual percentage changeDistant metastasisClinical presentationOverall survival of adult patientsAbsence of tumor necrosisSensitive to systemic therapySurvival of adult patientsNegative surgical marginsCornerstone of therapyMalignant rhabdoid tumorLower T stagePrimary renal sarcomaAssociated with younger ageAge-adjusted incidence ratesNCDB databaseLonger OSSurgical marginsSystemic therapyAnnual percentage changeRenal malignancy
2021
Renal sarcomas: Epidemiology, treatment and outcomes.
Uhlig J, Uhlig A, Deshpande H, Hurwitz M, Humphrey P, Kim K. Renal sarcomas: Epidemiology, treatment and outcomes. Journal Of Clinical Oncology 2021, 39: 362-362. DOI: 10.1200/jco.2021.39.6_suppl.362.Peer-Reviewed Original ResearchPrimitive neuroectodermal tumorRenal sarcomaOverall survivalMalignant rhabdoid tumorSEER databaseSurgical resectionSystemic therapyDistant metastasisTumor diameterSarcoma subtypesIncidence rateRenal malignancyAge-adjusted incidence ratesCox proportional hazards modelMedian tumor diameterAdvanced T stageDifferent histological subtypesProportional hazards modelSolitary fibrous tumorWorse OSAdult patientsFemale predominanceMale predominanceMedian ageOS rates
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