2025
Letter: Food and Drug Administration Clearance of Transcranial Magnetic Stimulation for Adolescent Depression in the Absence of Data Supporting Efficacy
Kumpf K, Hughes M, Bloch M. Letter: Food and Drug Administration Clearance of Transcranial Magnetic Stimulation for Adolescent Depression in the Absence of Data Supporting Efficacy. Journal Of Child And Adolescent Psychopharmacology 2025 PMID: 40275809, DOI: 10.1089/cap.2024.0142.Commentaries, Editorials and LettersAdolescent depressionTranscranial magnetic stimulationInterpersonal Emotion Regulation and Depressive Symptoms in Parent–Adolescent Dyads: A Daily-Diary Investigation
Gadassi-Polack R, Questel M, Sened H, Marshall H, Chen G, Geiger E, Yosef T, Joormann J. Interpersonal Emotion Regulation and Depressive Symptoms in Parent–Adolescent Dyads: A Daily-Diary Investigation. Emotion 2025, 25: 473-487. PMID: 39325395, PMCID: PMC11895396, DOI: 10.1037/emo0001418.Peer-Reviewed Original ResearchAdolescent depressionParent-adolescent dyadsDepressive symptomsActor-partner interdependence model frameworkAssociated with adolescent depressionAssociated with more depressionInterpersonal emotion regulationAssociated with higher levelsDaily-diaryEmotion regulationPositive affectParental depressionDyadic designDyadic processesDepression developmentDyad membersDaily diariesDecreased depressionDepressionParental useAdolescentsAdolescent useSymptomsDyadsParentsOral microbiota among treatment-naïve adolescents with depression: A case-control study
Zeng Y, Jia X, Li H, Zhou N, Liang X, Liu K, Yang B, Xiang B. Oral microbiota among treatment-naïve adolescents with depression: A case-control study. Journal Of Affective Disorders 2025, 375: 93-102. PMID: 39855566, PMCID: PMC11934967, DOI: 10.1016/j.jad.2025.01.089.Peer-Reviewed Original ResearchMajor depressive disorderArea under the curveCognitive functionOral microbiotaCase-control studyReceiver Operating CharacteristicAdolescent depressionDSM-5 major depressive disorderAssociated with major depressive disorderTreatment naive individualsNon-depressed individualsMorning saliva samplesHealthy control groupGroup of adolescentsDepressive disorderDSM-5Visual breadthDelayed memoryDepression groupOral healthOral bacteriaHC individualsGut microbiota changesHC groupOral microbesExamining the effects of school–vacation transitions on depression and anxiety in adolescents: network analysis
Ju Y, Yang Y, Yuan R, Chen Y, Liu J, Ou W, Li Y, Yang S, Lu Y, Li L, Huang M, Ma M, Lv G, Zhao X, Qing Y, Liu J, Zhang Y. Examining the effects of school–vacation transitions on depression and anxiety in adolescents: network analysis. BJPsych Open 2025, 11: e19. PMID: 39819964, PMCID: PMC11795178, DOI: 10.1192/bjo.2024.806.Peer-Reviewed Original ResearchAnxiety symptomsSymptom network structureAdolescent studentsPsychological statePatterns of depressionStudents' psychological stateBridge symptomsLongitudinal risk factorsPsychomotor disturbanceAdolescent depressionCentral symptomsState of adolescentsStudents' depressionAnxietyDepressionAnxiety levelsIntervention targetsFather's education levelEducation levelSchool yearMultilevel mixed-effects modelsMother's education levelSchool periodAdolescentsSchool
2024
Mentalization-Based Treatment for Adolescent Depression.
Luyten P, Malcorps S, Fonagy P. Mentalization-Based Treatment for Adolescent Depression. Psychodynamic Psychiatry 2024, 52: 490-511. PMID: 39679698, DOI: 10.1521/pdps.2024.52.4.490.Peer-Reviewed Original ResearchConceptsMentalization-based treatmentHistory of attachment traumaSeverity of depressionTreatment of depressionTreatment of adolescentsMental health problemsLong-term impairmentAttachment traumaAdolescent depressionPsychological interventionsMental perspectiveDepressionAdolescentsMental approachSpectrum of severityMentalMeta-analysesSevere endHealth problemsRelated problemsEmpirical evidenceImpairmentPersonsThoughtsTreatmentTask–Rest Reconfiguration Efficiency of the Reward Network Across Adolescence and Its Association With Early Life Stress and Depressive Symptoms
Lee Y, Yuan J, Winkler A, Kircanski K, Pine D, Gotlib I. Task–Rest Reconfiguration Efficiency of the Reward Network Across Adolescence and Its Association With Early Life Stress and Depressive Symptoms. Journal Of The American Academy Of Child & Adolescent Psychiatry 2024, 64: 290-300. PMID: 38878818, PMCID: PMC11638404, DOI: 10.1016/j.jaac.2024.04.018.Peer-Reviewed Original ResearchEarly life stressReward networkDepressive symptomsLife stressReconfiguration efficiencyFunctional connectivityExperiences of early life stressExposure to early life stressEffects of early life stressTask-based fMRI scansHigher levels of depressive symptomsLevels of depressive symptomsSevere early life stressReward processingAge-related associationsFMRI scanningAdolescent depressionCommunity sampleTask demandsResting-stateAsymptomatic youthOlder adolescentsEffects of ageRewardBrain statesDoes Prospective Mental Imagery Predict Symptoms of Negative Affect and Anhedonia in Young People?
Hutchinson T, Riddleston L, Lavi I, Pile V, Meehan A, Shukla M, Lau J. Does Prospective Mental Imagery Predict Symptoms of Negative Affect and Anhedonia in Young People? Child Psychiatry & Human Development 2024, 1-11. PMID: 38704800, DOI: 10.1007/s10578-024-01695-1.Peer-Reviewed Original ResearchProspective mental imageryMental imageryNegative affectSymptoms of negative affectCross-lagged panel modelEmotional mental imageryCross-lagged pathsAdolescent depressionAnhedoniaAffectLevels of attritionPanel modelStability pathsDiverse populationsTime pointsYoung peopleDepressionVividnessAdolescentsImageryPeopleAttrition
2023
Short-term psychoanalytic psychotherapy with depressed adolescents: Comparing in-session interactions in good and poor outcome cases
Fiorini G, Bai Y, Fonagy P, Consortium T, Midgley N. Short-term psychoanalytic psychotherapy with depressed adolescents: Comparing in-session interactions in good and poor outcome cases. Psychotherapy Research 2023, 34: 991-1004. PMID: 37946369, DOI: 10.1080/10503307.2023.2270140.Peer-Reviewed Original ResearchShort-term psychoanalytic psychotherapyAdolescent Psychotherapy Q-SetPoor outcome casesOutcome casesYoung personMajor depressive disorderExploratory factor analysisDepressive disorderBetter outcomesAdolescent depressionDepressed adolescentsFactor 1Group differencesGood outcome casesFactor 2TherapistsFactor 3Session interactionPsychoanalytic psychotherapyPsychotherapy processPsychotherapy sessionsAdolescentsPersonsSessionsRole of angerIs Future Mental Imagery Associated with Reduced Impact of the COVID-19 Pandemic on Negative Affect and Anhedonic Symptoms in Young People?
Hutchinson T, Riddleston L, Pile V, Meehan A, Shukla M, Lau J. Is Future Mental Imagery Associated with Reduced Impact of the COVID-19 Pandemic on Negative Affect and Anhedonic Symptoms in Young People? Cognitive Therapy And Research 2023, 47: 168-180. PMID: 36779180, PMCID: PMC9899113, DOI: 10.1007/s10608-023-10352-1.Peer-Reviewed Original ResearchProspective mental imageryNegative affectPositive affectMental imageryReduced vividnessAssociated with increased negative affectSymptoms of negative affectAssociated with adolescent depressionSymptoms of anhedoniaEnhancing positive affectAssociated with increased symptomsAnhedonic symptomsPsychological treatmentAdolescent depressionPositive future imagesAnhedoniaRecent stressClinical populationsConcurrent relationshipsSelf-ReportImagery tasksVerbal techniquesAffectMental imagesYoung people
2022
Computational Modeling of Self-Referential Processing Reveals Domain General Associations with Adolescent Anxiety Symptoms
Castagna P, Waters A, Crowley M. Computational Modeling of Self-Referential Processing Reveals Domain General Associations with Adolescent Anxiety Symptoms. Research On Child And Adolescent Psychopathology 2022, 51: 455-468. PMID: 36580171, DOI: 10.1007/s10802-022-01012-1.Peer-Reviewed Original ResearchConceptsSelf-referential encoding taskSelf-referential processingSocial anxietyAnxiety symptomsNegative self-referential processingAdolescent anxiety symptomsPhysiological anxiety symptomsFacets of anxietySelf-report measuresChoice reaction timeReaction timeEncoding tasksEvidence accumulationTask performanceAdolescent depressionDrift-diffusion modelComputational modeling resultsSocial contextAnxietyAdolescentsLatent processProcessingGeneral associationComputational modelingDepressionSelfie Videos to Reduce Stigma and Increase Treatment Seeking Among Youths: Two Noninferiority Randomized Controlled Trials
Amsalem D, Jankowski SE, Pagdon S, Valeri L, Yang LH, Markowitz JC, Neria Y, Pescosolido BA, Dixon LB, Martin A. Selfie Videos to Reduce Stigma and Increase Treatment Seeking Among Youths: Two Noninferiority Randomized Controlled Trials. Psychiatric Services 2022, 74: 229-236. PMID: 36254455, DOI: 10.1176/appi.ps.20220168.Peer-Reviewed Original ResearchConceptsTreatment-seeking intentionsControl conditionBrief videoD effect sizesIntervention videoYoung adultsIllness-related stigmaMental health stigmaAdolescent depressionCohen's d effect sizesHealth stigmaStudy 2Study 1Treatment engagementThemes of recoveryAdolescentsEffect sizeShort videosRepeated-measures analysisStigmaIntentionSimilar efficacyAdultsVideoSocial media influencersDestigmatizing perceptions about Black adolescent depression: randomized controlled trial of brief social contact–based video interventions
Martin A, Calhoun A, Páez J, Amsalem D. Destigmatizing perceptions about Black adolescent depression: randomized controlled trial of brief social contact–based video interventions. Journal Of Child Psychology And Psychiatry 2022, 63: 1270-1278. PMID: 35066880, PMCID: PMC9307690, DOI: 10.1111/jcpp.13570.Peer-Reviewed Original ResearchConceptsDepression Stigma ScaleHelp-seeking intentionsBlack adolescent girlsAdolescent depressionAdolescent girlsIntervention interactionTreatment-seeking intentionsVideo interventionDepression-related stigmaNon-Black participantsRace perceptionEmotional problemsStigmatized groupsVideo conditionRisk youthDifferent response profilesStigmatized attitudeShort videosStigma ScaleParticipantsPerceptionIntentionWarmthOlder healthy volunteersIntervention
2017
Ventral Striatum Functional Connectivity as a Predictor of Adolescent Depressive Disorder in a Longitudinal Community-Based Sample
Pan P, Sato J, Salum G, Rohde L, Gadelha A, Zugman A, Mari J, Jackowski A, Picon F, Miguel E, Pine D, Leibenluft E, Bressan R, Stringaris A. Ventral Striatum Functional Connectivity as a Predictor of Adolescent Depressive Disorder in a Longitudinal Community-Based Sample. American Journal Of Psychiatry 2017, 174: 1112-1119. PMID: 28946760, PMCID: PMC10752293, DOI: 10.1176/appi.ajp.2017.17040430.Peer-Reviewed Original ResearchConceptsResting-state functional MRIIntrinsic functional connectivityDepressive disorderFunctional connectivityFunctional MRIReward networkFuture depressive disorderAdolescent depressive disordersLeft ventral striatumOnset of depressionBrain reward networksAberrant reward processingAttention deficit hyperactivity disorderDeficit hyperactivity disorderLongitudinal communityChildren 6Ventral striatumAdolescent depressionLogistic regressionHyperactivity disorderSubstance useYouth depressionDisordersDepressionFuture risk
2014
Depressive Disorders in Adolescents
Jeffreys M, Weersing V. Depressive Disorders in Adolescents. 2014, 147-161. DOI: 10.1002/9781394259359.ch10.Peer-Reviewed Original ResearchCognitive behavioral therapyAdolescent depressionModular cognitive behavioral therapyPattern of resultsEvidence-based treatmentsInterpersonal psychotherapyDepressive disorderBehavioral therapyDepression courseLab-based settingsParental inclusionDiverse sampleDepressionStandardized assessmentParental involvementAdolescentsEffects of treatmentEvidence baseEvidence-based carePsychotherapyClinically relevant discussionDisordersProvision of evidence-based careEvidenceTreatment
2011
Maternal Postnatal Depression and the Development of Depression in Offspring Up to 16 Years of Age
Murray L, Arteche A, Fearon P, Halligan S, Goodyer I, Cooper P. Maternal Postnatal Depression and the Development of Depression in Offspring Up to 16 Years of Age. Journal Of The American Academy Of Child & Adolescent Psychiatry 2011, 50: 460-470. PMID: 21515195, DOI: 10.1016/j.jaac.2011.02.001.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild of Impaired ParentsChild, PreschoolDepression, PostpartumDepressive Disorder, MajorDysthymic DisorderFamily ConflictFemaleHumansInfantInterview, PsychologicalLife Change EventsLongitudinal StudiesMaleMass ScreeningObject AttachmentProspective StudiesResilience, PsychologicalRisk FactorsSocial SupportConceptsYears of ageDepressed mothersPostnatal depressionClinical depressionAdolescent depressionFamily adversityMain study outcomeMaternal postnatal depressionDevelopment of depressionProspective longitudinal studyDevelopmental risk pathwayIndex mothersOffspring riskProbable casesNondepressed mothersStudy outcomesChild vulnerabilityInsecure infant attachmentDepressionMothersLongitudinal studyRisk pathwaysFamily assessmentDevelopmental riskRisk
2006
Neurobiology of Depression in Children and Adolescents
Zalsman G, Oquendo MA, Greenhill L, Goldberg PH, Kamali M, Martin A, Mann JJ. Neurobiology of Depression in Children and Adolescents. Child And Adolescent Psychiatric Clinics Of North America 2006, 15: 843-868. PMID: 16952764, DOI: 10.1016/j.chc.2006.05.010.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdrenocorticotropic HormoneAnxiety DisordersBrainChildCognitive Behavioral TherapyCorticotropin-Releasing HormoneDepressive DisorderEstradiolFemaleHuman Growth HormoneHumansHypothalamo-Hypophyseal SystemMagnetic Resonance ImagingMaleNeurotransmitter AgentsPituitary-Adrenal SystemPrevalencePubertyRisk FactorsTestosteroneGained in Translation: Evidence-Based Medicine Meets Pediatric Psychopharmacology
Srihari V, Martin A. Gained in Translation: Evidence-Based Medicine Meets Pediatric Psychopharmacology. Child And Adolescent Psychiatric Clinics Of North America 2006, 15: 263-287. PMID: 16321734, DOI: 10.1016/j.chc.2005.08.001.Peer-Reviewed Original Research
1991
Depression in Adolescents Context, Manifestations, and Clinical Management
Sadler L. Depression in Adolescents Context, Manifestations, and Clinical Management. Nursing Clinics Of North America 1991, 26: 559-572. PMID: 1891392, DOI: 10.1016/s0029-6465(22)00269-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDepressed adolescentsMode of treatmentFuture depressive episodesPsychopharmacologic agentsDepressive episodeClinical managementEarly treatmentDepressive symptomsBiologic factorsSuicidal ideationAdolescent depressionSubstance abuseSocioeconomic statusSexual activityDepressionManifestationsThorough assessmentCareDisordersGroup psychotherapyTreatmentEthnic backgroundAdolescent contextAdolescentsSuicide
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