2025
Intranasal oxytocin increases breast milk oxytocin, but has a reduced effect in depressed mothers: A randomized controlled trialcon
Lindley Baron-Cohen K, Fearon P, Feldman R, Hardiman P, Zagoory-Sharon O, Meins E, Fonagy P. Intranasal oxytocin increases breast milk oxytocin, but has a reduced effect in depressed mothers: A randomized controlled trialcon. Psychoneuroendocrinology 2025, 174: 107374. PMID: 39891981, DOI: 10.1016/j.psyneuen.2025.107374.Peer-Reviewed Original ResearchConceptsEdinburgh Postnatal Depression ScaleBreast milkPostnatal depressionSymptoms of postnatal depressionAdministration of exogenous OTOT concentrationsCut-off pointRandomized Controlled TrialsPostnatal Depression ScalePostnatal depressive symptomsDouble-blindNasal sprayMother-infant bondingPotential biological mechanismsMaternal postnatal depressionOT contentBreast milk samplesMental health vulnerabilitiesOT pathwaysExogenous OTOT administrationControl mothersBreastDepressed mothersOxytocin
2020
Maternal mental health modifies the association of food insecurity and early child development
Pedroso J, Buccini G, Venancio SI, Pérez‐Escamilla R, Gubert MB. Maternal mental health modifies the association of food insecurity and early child development. Maternal And Child Nutrition 2020, 16: e12997. PMID: 32351004, PMCID: PMC7507582, DOI: 10.1111/mcn.12997.Peer-Reviewed Original ResearchConceptsChild development delaySevere household food insecurityMaternal depressionHousehold food insecurityEarly child developmentDevelopment delayDepressed mothersPrimary health centersMother-infant pairsCross-sectional studyLogistic regression analysisSecure householdsStrength of associationFood insecurityFood secure householdsRisk factorsHealth centersHigher oddsChild developmentPearson χInfantsSevere foodIntervention packageDepressionRegression analysis
2018
Primary parental preoccupation: revisited
Leckman J, Feldman R, Swain J, Mayes L. Primary parental preoccupation: revisited. 2018, 89-115. DOI: 10.4324/9780429473654-6.Peer-Reviewed Original ResearchSpecial mental stateBrain systemsMaternal behaviorBasic cognitive capacitiesChild attachment securitySecure attachment relationshipsDifferent brain systemsRelevant brain systemsInter-generational transmissionShort-term behavioral interventionAttachment securityParental preoccupationAttachment relationshipsIndividual differencesBody of researchCognitive capacityParental sensitivityMental statesCognitive characterizationVan IJzendoornBehavioral interventionsDepressed mothersTwin studiesPrimary maternal preoccupationMaternal preoccupation
2015
Postnatal Depression, Mother–Infant Interactions, and Child Development
Murray L, Fearon P, Cooper P. Postnatal Depression, Mother–Infant Interactions, and Child Development. 2015, 139-164. DOI: 10.1002/9781118509722.ch9.Peer-Reviewed Original ResearchMother-child relationshipChild outcomesMaternal depressionSocio-emotional developmentPoor child outcomesMother-infant interactionPostnatal depressionAdverse child outcomesDevelopment of childrenPsychological functioningChildren's problemsChild developmentDepressed mothersDepressionRoutine clinical practiceEvidence-based measuresConsiderable bodyDifficultiesMaternal disordersParentingEffective treatmentClinical practiceNumber of areasFurther evidenceFunctioning
2014
Telomere length and cortisol reactivity in children of depressed mothers
Gotlib I, LeMoult J, Colich N, Foland-Ross L, Hallmayer J, Joormann J, Lin J, Wolkowitz O. Telomere length and cortisol reactivity in children of depressed mothers. Molecular Psychiatry 2014, 20: 615-620. PMID: 25266121, PMCID: PMC4419149, DOI: 10.1038/mp.2014.119.Peer-Reviewed Original ResearchConceptsMajor depressive disorderMedical illnessTelomere lengthDepressed mothersHPA axis activityOnset of depressionCortisol reactivityShort telomeresRecurrent episodesCortisol secretionDepressive disorderHistory of psychopathologyCortisol levelsOnset of disorderFamilial riskLaboratory stressorGreater cortisol reactivityDepressionImplicating dysregulationMothersIllnessDisordersPresent studyChildrenRisk
2011
Maternal Postnatal Depression and the Development of Depression in Offspring Up to 16 Years of Age
Murray L, Arteche A, Fearon P, Halligan S, Goodyer I, Cooper P. Maternal Postnatal Depression and the Development of Depression in Offspring Up to 16 Years of Age. Journal Of The American Academy Of Child & Adolescent Psychiatry 2011, 50: 460-470. PMID: 21515195, DOI: 10.1016/j.jaac.2011.02.001.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild of Impaired ParentsChild, PreschoolDepression, PostpartumDepressive Disorder, MajorDysthymic DisorderFamily ConflictFemaleHumansInfantInterview, PsychologicalLife Change EventsLongitudinal StudiesMaleMass ScreeningObject AttachmentProspective StudiesResilience, PsychologicalRisk FactorsSocial SupportConceptsYears of ageDepressed mothersPostnatal depressionClinical depressionAdolescent depressionFamily adversityMain study outcomeMaternal postnatal depressionDevelopment of depressionProspective longitudinal studyDevelopmental risk pathwayIndex mothersOffspring riskProbable casesNondepressed mothersStudy outcomesChild vulnerabilityInsecure infant attachmentDepressionMothersLongitudinal studyRisk pathwaysFamily assessmentDevelopmental riskRisk
2010
Self-Efficacy as a Mediator Between Maternal Depression and Child Hospitalizations in Low-Income Urban Families
Holland ML, Yoo BK, Kitzman H, Chaudron L, Szilagyi PG, Temkin-Greener H. Self-Efficacy as a Mediator Between Maternal Depression and Child Hospitalizations in Low-Income Urban Families. Maternal And Child Health Journal 2010, 15: 1011-1019. PMID: 20706866, DOI: 10.1007/s10995-010-0662-z.Peer-Reviewed Original ResearchConceptsChild's hospitalizationMaternal depressionMedical recordsDepressive symptomsChildren's medical recordsElevated depressive symptomsMother-child pairsFirst child birthLogistic regression modelsHospitalizationDepressed mothersChild birthPotential mediatorsMinority womenDepressionBirthMediatorsSymptomsMonthsLow-income familiesRegression modelsLow-income urban familiesFurther researchUrban familiesTrials
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