2025
SA75 Foundational Insights and Costs of Care Associated With Perioperative Ticagrelor Management for Patients Undergoing Coronary Artery Bypass Graft Surgery: A Medical Chart Audit Review
Riello R, England C, Kulkarni A, Abilash V, Oak B, O'Hara M, McKenney J, Evans-Shields J, Fanikos J. SA75 Foundational Insights and Costs of Care Associated With Perioperative Ticagrelor Management for Patients Undergoing Coronary Artery Bypass Graft Surgery: A Medical Chart Audit Review. Value In Health 2025, 28: s409. DOI: 10.1016/j.jval.2025.04.1830.Peer-Reviewed Original ResearchMedical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis
Ryan M, Petrie M, Kontopantelis E, Dodd M, Tong G, Marquis-Gravel G, Docherty K, Clayton T, Lansky A, Mamas M, Rouleau J, Velazquez E, Perera D. Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis. European Heart Journal 2025, 46: 2052-2062. PMID: 40048661, PMCID: PMC12146480, DOI: 10.1093/eurheartj/ehaf080.Peer-Reviewed Original ResearchCoronary Artery Bypass GraftingPercutaneous coronary interventionMedical therapyPrimary outcome eventFollow-upPrimary outcomePatients treated with coronary artery bypass graftingOutcome eventsIndividual patient data analysisCoronary artery bypass graft surgeryIschaemic left ventricular dysfunctionMedian Follow-UpMulticentre randomized trialLeft ventricular dysfunctionOutcomes of patientsBenefit of coronary artery bypass graftingCompleteness of follow-upArtery Bypass GraftingCoronary artery diseasePatient data analysisIschaemic cardiomyopathyVentricular dysfunctionSurgical treatmentHeart failurePooled analysis
2024
Association between lipoprotein levels and outcomes after coronary artery bypass grafting surgery: a systematic review and meta-analysis.
Cancelli G, Harik L, Ibrahim M, Hameed I, Rossi C, Caldonazo T, Dell'aquila M, Soletti G, An K, Leith J, Demetres M, Dimagli A, Gaudino M. Association between lipoprotein levels and outcomes after coronary artery bypass grafting surgery: a systematic review and meta-analysis. Minerva Cardioangiologica 2024 PMID: 38842243, DOI: 10.23736/s2724-5683.24.06534-7.Peer-Reviewed Original ResearchCoronary Artery Bypass GraftingCoronary artery bypass graft patientsGraft occlusionMeta-analysisCardiovascular eventsAssociated with graft occlusionRisk of vascular inflammationIncreased risk of graft occlusionRisk of graft occlusionCoronary artery bypass graft surgeryLow serum Lp(aArtery bypass graft surgeryAssociated with local inflammationStudy-level meta-analysisMajor adverse cardiovascular eventsAssociated with increased riskPost-operative mortalityImpact of Lp(aAdverse cardiovascular eventsBypass graft surgeryArtery Bypass GraftingLow-density lipoprotein (LDLComprehensive literature searchStatistically significant differenceCut-offRisk Score for Long-Term Survival and Major Adverse Cardiovascular and Cerebrovascular Events After Coronary Artery Bypass Grafting Surgery
Dokollari A, Rosati F, Muneretto C, Amabile A, Pernoci M, Gemelli M, Hassanabad A, Sicouri S, Sicouri N, Yamashita Y, Baudo M, Bonacchi M, Cabrucci F, Bacchi B, Ghorpade N, Shah A, Coku L, Cameli M, Mandoli G, Kjelstrom S, Montone G, Wertan M, Ramlawi B, DiMagli A, Sutter F. Risk Score for Long-Term Survival and Major Adverse Cardiovascular and Cerebrovascular Events After Coronary Artery Bypass Grafting Surgery. The American Journal Of Cardiology 2024, 225: 10-21. PMID: 38608800, DOI: 10.1016/j.amjcard.2024.03.039.Peer-Reviewed Original ResearchIsolated Coronary Artery Bypass GraftingCoronary Artery Bypass GraftingRisk scoreLong-term survivalCoronary risk scoreFollow-upExternal validationAll-Cause MortalityCoronary artery bypass graft surgeryArtery bypass graft surgeryAfrican American ethnicityAll-CauseBypass graft surgeryArtery Bypass GraftingLong-term mortalityYear Follow-UpPredictive risk scoreRisk score modelAmerican ethnicityGraft surgeryBypass GraftingCerebrovascular eventsRisk predictorsMyocardial infarctionBootstrap cross-validation
2022
Effects of Melatonin on Cardiac Injury and Inflammatory Biomarkers in Patients Undergoing Coronary Artery Bypass Graft Surgery: a Meta-analysis
Farshidianfar M, Ardekani A, Tabrizi R, Lankarani K, Taherifard E, Abdollahi A, Azizi A, Akbari M. Effects of Melatonin on Cardiac Injury and Inflammatory Biomarkers in Patients Undergoing Coronary Artery Bypass Graft Surgery: a Meta-analysis. Cardiology And Therapy 2022, 12: 11-20. PMID: 36352301, PMCID: PMC9986370, DOI: 10.1007/s40119-022-00287-1.Peer-Reviewed Original ResearchCardiac injuryInflammatory biomarkersEffects of melatoninCABG candidatesCoronary artery bypass graft surgeryArtery bypass graft surgeryPost-coronary artery bypass graftingMelatonin supplementationReduce cardiac injuryBypass graft surgeryArtery Bypass GraftingCardiac troponin IRandom-effects modelRandomized Controlled TrialsCABG patientsGraft surgeryCABG surgeryBypass GraftingClinical significanceTroponin IWeb of ScienceCochrane LibraryControlled TrialsEgger's testCABG
2021
2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
Members W, Lawton J, Tamis-Holland J, Bangalore S, Bates E, Beckie T, Bischoff J, Bittl J, Cohen M, DiMaio J, Don C, Fremes S, Gaudino M, Goldberger Z, Grant M, Jaswal J, Kurlansky P, Mehran R, Metkus T, Nnacheta L, Rao S, Sellke F, Sharma G, Yong C, Zwischenberger B. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Journal Of The American College Of Cardiology 2021, 79: e21-e129. PMID: 34895950, DOI: 10.1016/j.jacc.2021.09.006.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseArtery diseaseCoronary revascularizationACC/AHA/SCAI GuidelineCoronary artery bypass graft surgeryArtery bypass graft surgerySignificant coronary artery diseaseBypass graft surgeryCoronary artery revascularizationClinical practice guidelinesImportant therapeutic optionTreatment of patientsAdditional relevant studiesQuality of careComprehensive literature searchEvidence-based approachArtery revascularizationPatient-centric approachRevascularization guidelinesGraft surgeryCochrane CollaborationTherapeutic optionsLeading causePractice guidelinesAmerican CollegeTransesophageal Echocardiography in Patients Undergoing Coronary Artery Bypass Graft Surgery
Metkus T, Thibault D, Grant M, Badhwar V, Jacobs J, Lawton J, O'Brien S, Thourani V, Wegermann Z, Zwischenberger B, Higgins R. Transesophageal Echocardiography in Patients Undergoing Coronary Artery Bypass Graft Surgery. Journal Of The American College Of Cardiology 2021, 78: 112-122. PMID: 33957241, PMCID: PMC8876254, DOI: 10.1016/j.jacc.2021.04.064.Peer-Reviewed Original ResearchConceptsIntraoperative transesophageal echocardiographyHigh-risk patientsTransesophageal echocardiographyCABG patientsOperative mortalityValve proceduresCoronary artery bypass graft surgeryThoracic Surgeons Adult Cardiac Surgery DatabaseArtery bypass graft surgeryAdult Cardiac Surgery DatabasePost-CABG mortalityBypass graft surgeryCoronary artery bypassRetrospective cohort studyLow operative mortalityPercentage of patientsCardiac Surgery DatabaseClinical decision makingArtery bypassGraft surgeryValve surgeryCohort studyCABG proceduresPrimary outcomeSurgery DatabaseAdministrative Claims Measure for Profiling Hospital Performance Based on 90-Day All-Cause Mortality Following Coronary Artery Bypass Graft Surgery
Mori M, Nasir K, Bao H, Jimenez A, Legore SS, Wang Y, Grady J, Lama SD, Brandi N, Lin Z, Kurlansky P, Geirsson A, Bernheim SM, Krumholz HM, Suter LG. Administrative Claims Measure for Profiling Hospital Performance Based on 90-Day All-Cause Mortality Following Coronary Artery Bypass Graft Surgery. Circulation Cardiovascular Quality And Outcomes 2021, 14: e006644. PMID: 33535776, DOI: 10.1161/circoutcomes.120.006644.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesCoronary artery bypass graft surgeryArtery bypass graft surgeryBypass graft surgeryMortality rateGraft surgeryC-statisticMedicaid ServicesAdministrative Claims MeasureCause mortality ratesMortality measuresUnadjusted mortality ratesProfiling Hospital PerformanceHierarchical logistic regression modelsAlternate payment modelsHospital performanceLogistic regression modelsCABG recoveryPayment modelsCABG surgeryCause mortalityCABG proceduresDays postsurgeryHospital levelSurgery
2020
Associations Between the Severity of Influenza Seasons and Mortality and Readmission Risks After Elective Surgical Aortic Valve Replacement and Coronary Artery Bypass Graft Surgery in Older Adults
Mori M, Wang Y, Mahajan S, Geirsson A, Krumholz HM. Associations Between the Severity of Influenza Seasons and Mortality and Readmission Risks After Elective Surgical Aortic Valve Replacement and Coronary Artery Bypass Graft Surgery in Older Adults. JAMA Network Open 2020, 3: e2031078. PMID: 33355673, PMCID: PMC7758803, DOI: 10.1001/jamanetworkopen.2020.31078.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementElective surgical aortic valve replacementAortic valve replacementValve replacementReadmission riskCoronary artery bypass graft surgeryArtery bypass graft surgeryOlder adultsBypass graft surgeryCoronary artery bypassCross-sectional studyArtery bypassGraft surgeryInfluenza seasonMedicaid ServicesMortalitySeverityAdultsRiskAssociationSurgeryBypassTrends in Reoperative Coronary Artery Bypass Graft Surgery for Older Adults in the United States, 1998 to 2017
Mori M, Wang Y, Murugiah K, Khera R, Gupta A, Vallabhajosyula P, Masoudi FA, Geirsson A, Krumholz HM. Trends in Reoperative Coronary Artery Bypass Graft Surgery for Older Adults in the United States, 1998 to 2017. Journal Of The American Heart Association 2020, 9: e016980. PMID: 33045889, PMCID: PMC7763387, DOI: 10.1161/jaha.120.016980.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graft surgeryFirst-time coronary artery bypass graft surgeryArtery bypass graft surgeryBypass graft surgeryGraft surgeryMedicare feeOlder adultsPatient baseline characteristicsData of adultsYear of dischargeProportion of womenService inpatientsIndex surgeryBaseline characteristicsHospital dischargeOlder patientsMedian agePrimary outcomeCox regressionService patientsUnique patientsPatientsSurgeryAnnual declineDemographic subgroupsDepression predicts cognitive and functional decline one month after coronary artery bypass graft surgery (Neuropsychiatric Outcomes After Heart Surgery study)
Oldham MA, Lin I, Hawkins KA, Li F, Yuh DD, Lee HB. Depression predicts cognitive and functional decline one month after coronary artery bypass graft surgery (Neuropsychiatric Outcomes After Heart Surgery study). International Journal Of Geriatric Psychiatry 2020, 36: 452-460. PMID: 33022808, PMCID: PMC9326959, DOI: 10.1002/gps.5443.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graft surgeryArtery bypass graft surgeryBypass graft surgeryCABG surgeryGraft surgeryCDR-SBProspective observational cohort studyOlder ageOne monthHamilton Depression Rating ScaleClinical Dementia Rating SumHeart Surgery studyObservational cohort studyDepression Rating ScaleSemi-structured clinical interviewTotal study sampleHopkins Verbal Learning TestPostoperative deliriumPreoperative depressionWord Fluency TestCohort studyVerbal Learning TestNeuropsychiatric outcomesTertiary careFunctional outcomeThe association of statins for secondary prevention with progression to diabetes in patients with prediabetic state after coronary artery bypass graft surgery: A retrospective cohort study
Poorhosseini H, Tavolinejad H, Aminorroaya A, Soleimani H, Aasham O, Jalali A, Mohammadi A, Beigi S, Sadeghian S, Bagheri J, Tajdini M. The association of statins for secondary prevention with progression to diabetes in patients with prediabetic state after coronary artery bypass graft surgery: A retrospective cohort study. Journal Of Diabetes And Its Complications 2020, 34: 107713. PMID: 32900589, DOI: 10.1016/j.jdiacomp.2020.107713.Peer-Reviewed Original ResearchConceptsCoronary Artery Bypass GraftingOccurrence of MACEPost-CABG patientsCumulative doseSecondary prevention of coronary artery diseaseSecondary preventionCoronary artery bypass graft surgeryPrevention of coronary artery diseaseArtery bypass graft surgeryFamily history of T2DMDoses of statinsTime of surgeryAssociation of statinsType 2 diabetes mellitusComposite of deathOccurrence of type 2 diabetes mellitusAdverse cardiovascular eventsBenefits of statinsBypass graft surgeryHistory of hypertensionHistory of T2DMArtery Bypass GraftingBody mass indexCoronary artery diseaseProgression to diabetesRelationship Between Hospital Surgical Aortic Valve Replacement Volume and Transcatheter Aortic Valve Replacement Outcomes
Hirji S, McCarthy E, Kim D, McGurk S, Ejiofor J, Val F, Kolkailah A, Rosner B, Shook D, Nyman C, Berry N, Sobieszczyk P, Pelletier M, Shah P, O’Gara P, Kaneko T. Relationship Between Hospital Surgical Aortic Valve Replacement Volume and Transcatheter Aortic Valve Replacement Outcomes. JACC Cardiovascular Interventions 2020, 13: 335-343. PMID: 32029250, PMCID: PMC8858441, DOI: 10.1016/j.jcin.2019.09.048.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveClinical CompetenceDatabases, FactualFemaleHeart Valve Prosthesis ImplantationHospitals, High-VolumeHospitals, Low-VolumeHumansMaleMedicareOutcome and Process Assessment, Health CareQuality Indicators, Health CareRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementSurgical aortic valve replacementTranscatheter Aortic Valve Replacement OutcomesAortic valve replacementValve replacementConcomitant coronary artery bypass graft surgeryGroup 2Aortic valve replacement volumesGroup 1Group 3Group 4Surgical aortic valve replacement volumeCoronary artery bypass graft surgeryTranscatheter aortic valve replacement procedureArtery bypass graft surgeryAortic valve replacement proceduresYear post-procedureOpen-heart proceduresRisk-adjusted odds ratioMultivariate Cox regressionHeart valve proceduresLow-volume centersValve replacement proceduresTAVR admissionsBypass graft surgery
2019
DEPRESSION PREDICTS DELIRIUM AFTER CORONARY ARTERY BYPASS GRAFT SURGERY INDEPENDENT OF COGNITIVE IMPAIRMENT AND CEREBROVASCULAR DISEASE: AN ANALYSIS OF THE NOAHS STUDY
Lin I, Oldham M, Hawkins K, Scoutt L, Yuh D, Lee H. DEPRESSION PREDICTS DELIRIUM AFTER CORONARY ARTERY BYPASS GRAFT SURGERY INDEPENDENT OF COGNITIVE IMPAIRMENT AND CEREBROVASCULAR DISEASE: AN ANALYSIS OF THE NOAHS STUDY. American Journal Of Geriatric Psychiatry 2019, 27: s160-s161. DOI: 10.1016/j.jagp.2019.01.113.Peer-Reviewed Original ResearchMiddle cerebral arteryMild cognitive impairmentCerebrovascular diseaseCognitive impairmentRisk factorsCoronary artery bypass graft surgeryStenosis severityArtery bypass graft surgeryBilateral middle cerebral arteriesPreoperative cognitive assessmentBypass graft surgeryConfusion Assessment MethodCoronary artery bypassRisk of deliriumDelirium risk factorsObservational cohort studyPostoperative day 2Clinical Dementia RatingPutative risk factorsResults Average ageCI 1.3Preoperative depressionStructured HamiltonStudy psychiatristArtery bypassTwenty-Year Trends in Outcomes for Older Adults With Acute Myocardial Infarction in the United States
Krumholz HM, Normand ST, Wang Y. Twenty-Year Trends in Outcomes for Older Adults With Acute Myocardial Infarction in the United States. JAMA Network Open 2019, 2: e191938. PMID: 30874787, PMCID: PMC6484647, DOI: 10.1001/jamanetworkopen.2019.1938.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionRecurrent acute myocardial infarctionPercutaneous coronary interventionAMI dischargeCause readmissionCoronary interventionMyocardial infarctionMedicare feeCoronary artery bypass graft surgery ratesCoronary artery bypass graft surgeryArtery bypass graft surgeryInpatient percutaneous coronary interventionRate of catheterizationBypass graft surgeryShort-term mortalityInpatient paymentsQuality of careTwenty-year trendsEvolution of outcomesHospital mortalityHospital stayInpatient outcomesCause mortalityGraft surgeryCohort studyPredictors of Cardiac Surgery Patients Who Tolerate Blood Conservation in Cardiac Surgery
Mori M, Zhuo H, Liu F, LaLonde M, Pelletier KJ, Agarwal R, Geirsson A, Karimi M, Haddadin A, Bonde P, Zhang Y, Mangi AA. Predictors of Cardiac Surgery Patients Who Tolerate Blood Conservation in Cardiac Surgery. The Annals Of Thoracic Surgery 2019, 107: 1737-1746. PMID: 30639361, DOI: 10.1016/j.athoracsur.2018.11.070.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graft surgeryArtery bypass graft surgeryBlood conservation interventionsBypass graft surgeryAortic valve replacementBlood conservationPatient characteristicsPostintervention cohortGraft surgeryValve replacementPreintervention cohortPatient populationConcomitant coronary artery bypass graft surgeryCardiac surgical patient populationPerioperative blood product useRed blood cell transfusionBlood product usePostoperative renal failureBlood cell transfusionCardiac surgery patientsSurgical patient populationCardiopulmonary bypass useSelect patient populationsBody mass indexBlood conservation efforts
2018
Depression Predicts Delirium After Coronary Artery Bypass Graft Surgery Independent of Cognitive Impairment and Cerebrovascular Disease: An Analysis of the Neuropsychiatric Outcomes After Heart Surgery Study
Oldham MA, Hawkins KA, Lin IH, Deng Y, Hao Q, Scoutt LM, Yuh DD, Lee HB. Depression Predicts Delirium After Coronary Artery Bypass Graft Surgery Independent of Cognitive Impairment and Cerebrovascular Disease: An Analysis of the Neuropsychiatric Outcomes After Heart Surgery Study. American Journal Of Geriatric Psychiatry 2018, 27: 476-486. PMID: 30709616, PMCID: PMC6443412, DOI: 10.1016/j.jagp.2018.12.025.Peer-Reviewed Original ResearchConceptsMiddle cerebral arteryMild cognitive impairmentCerebrovascular diseaseCognitive impairmentRisk factorsCoronary artery bypass graft surgeryStenosis severityProspective observational cohort studyArtery bypass graft surgeryBilateral middle cerebral arteriesTertiary care academic hospitalHeart Surgery studyPreoperative cognitive assessmentUndergoing CABG surgeryBypass graft surgeryConfusion Assessment MethodRisk of deliriumDelirium risk factorsObservational cohort studyPostoperative day 2Clinical Dementia RatingDepression InterviewPreoperative depressionStructured HamiltonStudy psychiatrist
2017
Association of red blood cell transfusion and short- and longer-term mortality after coronary artery bypass graft surgery
Tantawy H, Li A, Dai F, Elgammal M, Sukumar N, Elefteriades J, Akhtar S. Association of red blood cell transfusion and short- and longer-term mortality after coronary artery bypass graft surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2017, 32: 1225-1232. PMID: 29402623, DOI: 10.1053/j.jvca.2017.12.033.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graft surgeryPacked red blood cellsArtery bypass graft surgeryRed blood cell transfusionTertiary care academic medical centerBypass graft surgeryBlood cell transfusionAcademic medical centerMortality rateCABG surgeryCell transfusionGraft surgeryMedical CenterAdult cardiac surgery patientsLong-term mortality outcomesRetrospective medical record reviewCardiothoracic intensive care unitPropensity Score Matching AnalysisCardiac surgery patientsLong-term mortalityMedical record reviewIntensive care unitSignificant differencesStatistical significant differenceHospital mortalityPattern and predictors of dual antiplatelet use after coronary artery bypass graft surgery
Mori M, Shioda K, Yun JJ, Mangi AA, Darr U, Geirsson A. Pattern and predictors of dual antiplatelet use after coronary artery bypass graft surgery. Journal Of Thoracic And Cardiovascular Surgery 2017, 155: 632-638. PMID: 29056263, DOI: 10.1016/j.jtcvs.2017.09.092.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedClinical Decision-MakingConnecticutCoronary Artery BypassDrug Administration ScheduleDrug Therapy, CombinationFemaleHemorrhageHumansMaleMiddle AgedPatient DischargePlatelet Aggregation InhibitorsPractice Patterns, Physicians'RecurrenceRetrospective StudiesRisk AssessmentRisk FactorsSurgeonsTime FactorsTreatment OutcomeConceptsDual antiplatelet therapy useCoronary artery bypassAntiplatelet therapy useDual antiplatelet therapyAcute coronary syndromePump coronary artery bypassArtery bypassTherapy useAntiplatelet therapyCoronary syndromeSurgeon preferenceMixed-effects multivariate logistic regressionCoronary artery bypass graft surgeryMixed-effects multivariate modelsArtery bypass graft surgeryCoronary Artery Bypass GraftingSingle-center retrospective reviewYale-New Haven HospitalDual antiplatelet useArtery Bypass GraftingBypass graft surgeryCurrent practice patternsMultivariate logistic regressionAntiplatelet useBypass GraftingFactors associated with postoperative atrial fibrillation and other adverse events after cardiac surgery
Akintoye E, Sellke F, Marchioli R, Tavazzi L, Mozaffarian D. Factors associated with postoperative atrial fibrillation and other adverse events after cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2017, 155: 242-251.e10. PMID: 28890081, DOI: 10.1016/j.jtcvs.2017.07.063.Peer-Reviewed Original ResearchConceptsPostoperative atrial fibrillationMajor adverse cardiovascular eventsCoronary artery bypassAdverse cardiovascular eventsArtery bypassAtrial fibrillationCardiovascular eventsCardiac surgeryHigh riskConcomitant valvularValvular surgeryCardiopulmonary bypassAdverse outcomesVentricular pacingBypass useCoronary artery bypass graft surgeryConcomitant coronary artery bypassArtery bypass graft surgeryBypass graft surgeryMultivariable-adjusted modelsCardiopulmonary bypass useType of surgeryData of patientsSpecific adverse outcomesSurgery characteristics
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