2025
Fair text to medical image diffusion model with subgroup distribution aligned tuning
Han X, Fan F, Rong J, Li Z, Fakhri G, Chen Q, Liu X. Fair text to medical image diffusion model with subgroup distribution aligned tuning. Proceedings Of SPIE--the International Society For Optical Engineering 2025, 13411: 1341113-1341113-5. PMID: 40831669, PMCID: PMC12360154, DOI: 10.1117/12.3046450.Peer-Reviewed Original ResearchContrastive Language-Image Pre-trainingMedical imagesDistribution alignment methodsKnowledge distillation frameworkImage synthesis modelMedical image dataGender classifierDistillation frameworkAlignment lossRegularization termApplication datasetsTarget datasetRepresentation inconsistenciesAppearance distributionsPre-trainingTraining datasetClassification probabilitiesBrain magnetic resonanceFine-tuningDatasetStatus descriptionBraTS18Image dataClassifierEvaluation purposes
2022
Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest
Beekman R, Crawford A, Mazurek MH, Prabhat AM, Chavva IR, Parasuram N, Kim N, Kim JA, Petersen N, de Havenon A, Khosla A, Honiden S, Miller PE, Wira C, Daley J, Payabvash S, Greer DM, Gilmore EJ, Kimberly W, Sheth KN. Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest. Resuscitation 2022, 176: 150-158. PMID: 35562094, PMCID: PMC9746653, DOI: 10.1016/j.resuscitation.2022.05.002.Peer-Reviewed Original ResearchConceptsCardiac arrestBrain injuryHypoxic-ischemic brain injuryAdverse neurological outcomesIschemic brain injurySingle-center studyBrain magnetic resonanceBrain injury severityBoard-certified neuroradiologistsLow-field MRIFLAIR signal intensityNeurological outcomeCA patientsIll patientsMRI findingsCA survivorsCenter studyMRI examinationsClinical careHigh riskInjury severityPatientsSignal intensityBedside monitoringMR imaging
2021
Idiopathic primary intraventricular hemorrhage and cerebral small vessel disease
Das A, Regenhardt R, Gokcal E, Horn M, Daoud N, Schwab K, Rost N, Viswanathan A, Kimberly W, Goldstein J, Biffi A, Schwamm L, Rosand J, Greenberg S, Gurol M. Idiopathic primary intraventricular hemorrhage and cerebral small vessel disease. International Journal Of Stroke 2021, 17: 645-653. PMID: 34427471, PMCID: PMC10947797, DOI: 10.1177/17474930211043957.Peer-Reviewed Original ResearchConceptsCerebral small vessel diseaseCerebral amyloid angiopathyPrimary intraventricular hemorrhageIdiopathic primary intraventricular hemorrhageProbable cerebral amyloid angiopathyAmyloid angiopathySmall vessel diseaseIntraventricular hemorrhageVessel diseaseMean initial blood pressureNon-traumatic intracerebral hemorrhageBrain magnetic resonance imagingInitial blood pressurePrimary intraparenchymal hemorrhageSingle referral centerBrain magnetic resonanceMagnetic resonance imagingCSVD subtypesBoston criteriaReferral centerBlood pressureConsecutive patientsCerebral amyloidIntracerebral hemorrhageIntraparenchymal hemorrhageRates of Incidental Findings in Brain Magnetic Resonance Imaging in Children
Li Y, Thompson WK, Reuter C, Nillo R, Jernigan T, Dale A, Sugrue LP, Brown J, Dougherty R, Rauschecker A, Rudie J, Barch D, Calhoun V, Hagler D, Hatton S, Tanabe J, Marshall A, Sher K, Heeringa S, Hermosillo R, Banich M, Squeglia L, Bjork J, Zucker R, Neale M, Herting M, Sheth C, Huber R, Reeves G, Hettema J, Howlett K, Cloak C, Baskin-Sommers A, Rapuano K, Gonzalez R, Karcher N, Laird A, Baker F, James R, Sowell E, Dick A, Hawes S, Sutherland M, Bagot K, Bodurka J, Breslin F, Morris A, Paulus M, Gray K, Hoffman E, Weiss S, Rajapakse N, Glantz M, Nagel B, Ewing S, Goldstone A, Pfefferbaum A, Prouty D, Rosenberg M, Bookheimer S, Tapert S, Infante M, Jacobus J, Giedd J, Shilling P, Wade N, Uban K, Haist F, Heyser C, Palmer C, Kuperman J, Hewitt J, Cottler L, Isaiah A, Chang L, Edwards S, Ernst T, Heitzeg M, Puttler L, Sripada C, Iacono W, Luciana M, Clark D, Luna B, Schirda C, Foxe J, Freedman E, Mason M, McGlade E, Renshaw P, Yurgelun-Todd D, Albaugh M, Allgaier N, Chaarani B, Potter A, Ivanova M, Lisdahl K, Do E, Maes H, Bogdan R, Anokhin A, Dosenbach N, Glaser P, Heath A, Casey B, Gee D, Garavan H, Dowling G, Brown S. Rates of Incidental Findings in Brain Magnetic Resonance Imaging in Children. JAMA Neurology 2021, 78: 578-587. PMID: 33749724, PMCID: PMC7985817, DOI: 10.1001/jamaneurol.2021.0306.Peer-Reviewed Original ResearchConceptsBrain magnetic resonance imagingMagnetic resonance imagingIncidental findingPediatric populationCommon incidental findingsGeneral pediatric populationBrain magnetic resonanceStructural magnetic resonance imagingLongitudinal observational studyBoard-certified neuroradiologistsUrgent medical interventionBaseline structural magnetic resonance imagingPercentage of childrenPotential clinical significanceNormal anatomic variantsCognitive Development StudyAdolescent Brain Cognitive Development (ABCD) studyCohort studyTwin gestationsOverall prevalenceNeurologic disordersAnatomic variantsClinical significanceObservational studyMAIN OUTCOME
2018
Longitudinal Effects of Alcohol Consumption on the Hippocampus and Parahippocampus in College Students
Meda SA, Hawkins KA, Dager AD, Tennen H, Khadka S, Austad CS, Wood RM, Raskin S, Fallahi CR, Pearlson GD. Longitudinal Effects of Alcohol Consumption on the Hippocampus and Parahippocampus in College Students. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2018, 3: 610-617. PMID: 29680476, PMCID: PMC6062479, DOI: 10.1016/j.bpsc.2018.02.006.Peer-Reviewed Original ResearchConceptsAlcohol consumptionAlcohol use indicesHippocampal volume declineBrain magnetic resonanceLongitudinal effectsMemory scoresCalifornia Verbal Learning Test-IIAlcohol-induced memory blackoutsPara-hippocampusHippocampal volumeMemory blackoutsLongitudinal brainVolume declineDrinking indicesLongitudinal pipelinePoorer memory performancePoorer memory scoresHippocampusTest IICross-sectional literatureDrinking-related measuresBrainAlcohol researchMagnetic resonanceScoresImplementation of a Rapid, Protocol-based TIA Management Pathway
Jarhult S, Howell M, Barnaure-Nachbar I, Chang Y, White B, Amatangelo M, Brown D, Singhal A, Schwamm L, Silverman S, Goldstein J. Implementation of a Rapid, Protocol-based TIA Management Pathway. Western Journal Of Emergency Medicine 2018, 19: 216-223. PMID: 29560046, PMCID: PMC5851491, DOI: 10.5811/westjem.2017.9.35341.Peer-Reviewed Original ResearchConceptsTransient ischemic attackTotal hospital LOSHospital LOSEmergency departmentED LOSFinal diagnosisRecurrent transient ischemic attacksTertiary care academic centerED observation unitIntermediate-risk patientsHigh-risk patientsProportion of patientsMedian ED LOSInpatient admission ratesNeck CT angiographyBrain magnetic resonanceNeck MR angiographyStandardized clinical protocolUse of neuroimagingIschemic attackCohort studyTIA symptomsConsecutive patientsED lengthSix-month period
2013
Lessons Learned From Fatal Progressive Multifocal Leukoencephalopathy in a Patient With Multiple Sclerosis Treated With Natalizumab
Boster AL, Nicholas JA, Topalli I, Kisanuki YY, Pei W, Morgan-Followell B, Kirsch CF, Racke MK, Pitt D. Lessons Learned From Fatal Progressive Multifocal Leukoencephalopathy in a Patient With Multiple Sclerosis Treated With Natalizumab. JAMA Neurology 2013, 70: 398-402. PMID: 23338729, DOI: 10.1001/jamaneurol.2013.1960.Peer-Reviewed Original ResearchConceptsProgressive multifocal leukoencephalopathyBrain magnetic resonance imagingMagnetic resonance imagingMultiple sclerosisResonance imagingMultifocal leukoencephalopathyPolymerase chain reaction testingFatal progressive multifocal leukoencephalopathyBenefits of natalizumabInfusions of natalizumabPML risk stratificationAntibody-positive patientsHigh-dose corticosteroidsCerebrospinal fluid studiesHigh clinical suspicionCerebrospinal fluid analysisBrain magnetic resonanceNegative test resultsPolymerase chain reaction resultsSubacute onsetBilateral blindnessClinical suspicionClinical vigilanceCortical demyelinationTherapy duration
2011
Hoofbeats and zebras: neurodegenerative disorder presenting as a “first episode” of psychosis
Ozkan B, Phutane V, Jonas E, Tek C, Srihari V. Hoofbeats and zebras: neurodegenerative disorder presenting as a “first episode” of psychosis. General Hospital Psychiatry 2011, 33: 412.e1-412.e3. PMID: 21762843, PMCID: PMC3139144, DOI: 10.1016/j.genhosppsych.2011.03.011.Peer-Reviewed Original ResearchConceptsNeurodegenerative disordersDiverse neuropsychiatric symptomsBrain magnetic resonanceProgressive cortical atrophyCortical atrophyPsychosis clinicNeuropsychiatric symptomsFirst episodeFrontal lobeAuditory hallucinationsBehavioral declineDisordersParanoid ideationMagnetic resonancePatientsAtrophyClinicSymptomsPsychosisHallucinations
1999
Childhood-onset schizophrenia: progressive brain changes during adolescence
Giedd J, Jeffries N, Blumenthal J, Castellanos FX, Vaituzis A, Fernandez T, Hamburger S, Liu H, Nelson J, Bedwell J, Tran L, Lenane M, Nicolson R, Rapoport J. Childhood-onset schizophrenia: progressive brain changes during adolescence. Biological Psychiatry 1999, 46: 892-898. PMID: 10509172, DOI: 10.1016/s0006-3223(99)00072-4.Peer-Reviewed Original ResearchConceptsBrain anomaliesVentricular volumeTotal cerebrumLateral ventricleCOS groupDuration of illnessProgressive brain changesBrain magnetic resonanceStructural brain anomaliesBrain MRI studiesGender-matched controlsMean age 14Age-related changesAdult patientsAdult schizophreniaBrain changesMRI studiesControl groupLarger sample sizeBrain tissueBrain developmentHippocampusProgressionDiagnostic group differencesEarly adulthoodProgressive Cortical Change During Adolescence in Childhood-Onset Schizophrenia: A Longitudinal Magnetic Resonance Imaging Study
Rapoport JL, Giedd JN, Blumenthal J, Hamburger S, Jeffries N, Fernandez T, Nicolson R, Bedwell J, Lenane M, Zijdenbos A, Paus T, Evans A. Progressive Cortical Change During Adolescence in Childhood-Onset Schizophrenia: A Longitudinal Magnetic Resonance Imaging Study. JAMA Psychiatry 1999, 56: 649-654. PMID: 10401513, DOI: 10.1001/archpsyc.56.7.649.Peer-Reviewed Original ResearchConceptsChildhood-onset schizophreniaCortical gray matter volumeWhite matter volumeDisease-specific patternsGray matter volumeMatter volumeHealthy controlsCortical changesBrain tissueGray matterSchizophrenia groupLongitudinal magnetic resonance imaging studyBrain developmentBrain ventricular enlargementProgressive cortical changesMagnetic resonance imaging studyBrain magnetic resonanceEarly-onset schizophreniaTemporal gray matterAbnormal brain developmentResonance imaging studyVentricular enlargementMean ageOnset schizophreniaPatient's illness
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