2022
Isolated Terminal Ileitis in Children
Alper A, Bennett A, Rottmann D, Morotti R, Escalera S, Phatak U, Pashankar D. Isolated Terminal Ileitis in Children. Journal Of Pediatric Gastroenterology And Nutrition 2022, 76: 338-342. PMID: 36729703, DOI: 10.1097/mpg.0000000000003679.Peer-Reviewed Original ResearchConceptsCrohn's diseaseTerminal ileitisAbnormal C-reactive protein levelsC-reactive protein levelsBowel wall thickeningLong-term outcomesRadiological evidenceRadiological featuresSevere inflammationPediatric literatureHigh prevalenceIleitisWall thickeningProtein levelsChildrenPrevalenceAdultsColonoscopyInflammationEndoscopicHistologicDiseaseMonthsTransurethral resection of posterior urethral valves
Arlen A. Transurethral resection of posterior urethral valves. Urology Video Journal 2022, 15: 100165. DOI: 10.1016/j.urolvj.2022.100165.Peer-Reviewed Original ResearchPosterior urethral valvesUrethral valvesVesicoureteral refluxLower urinary tract obstructionBladder neck hypertrophyBladder wall thickeningUpper tract dilationStage renal diseaseUrinary tract obstructionFetal development resultsTract obstructionRenal diseaseTransurethral resectionDetrusor hypertrophyTract dilationPosterior urethraCommon causeWall thickeningMost valvesHypertrophyDilationValveResectionUrethraObstructionFindings of Abdominal Imaging in Patients with COVID-19 Part 1: Hollow Organs
Langroudi A, Varniab Z, Amouei M, Pak N, Khosravi B, Mirsharifi A, Radmard A. Findings of Abdominal Imaging in Patients with COVID-19 Part 1: Hollow Organs. Middle East Journal Of Digestive Diseases 2022, 14: 278-286. PMID: 36619269, PMCID: PMC9489432, DOI: 10.34172/mejdd.2022.284.Peer-Reviewed Original ResearchAcute mesenteric ischemiaAbdominal imagingEarly diagnosis of AMIComputed tomographyDiagnosis of acute mesenteric ischemiaAbdominal computed tomographyFluid-filled colonAbdominal imaging modalitiesBowel wall thickeningHollow abdominal organsAbdominal CTAbdominal painCT angiographyCoagulation dysfunctionAbdominal symptomsMesenteric ischemiaGastrointestinal findingsHigh morbidityRespiratory manifestationsEarly diagnosisAbdominal organsPatientsAdmitted PatientsImaging modalitiesWall thickening
2021
Sex Differences in Inflammation During Venous Remodeling of Arteriovenous Fistulae
Chan SM, Weininger G, Langford J, Jane-Wit D, Dardik A. Sex Differences in Inflammation During Venous Remodeling of Arteriovenous Fistulae. Frontiers In Cardiovascular Medicine 2021, 8: 715114. PMID: 34368264, PMCID: PMC8335484, DOI: 10.3389/fcvm.2021.715114.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAVF maturationVenous remodelingSex differencesPre-menopausal womenArteriovenous fistula maturationFistula environmentFistula utilizationCardiovascular eventsArterial diseaseClinical presentationFistula maturationArteriovenous fistulaVascular accessArterial remodelingVascular disordersClinical studiesVascular remodelingAnimal modelsInflammationAVF successVessel dilationWall thickeningVascular therapyWomenRemodelingInhibition of T-Cells by Cyclosporine A Reduces Macrophage Accumulation to Regulate Venous Adaptive Remodeling and Increase Arteriovenous Fistula Maturation
Matsubara Y, Kiwan G, Liu J, Gonzalez L, Langford J, Gao M, Gao X, Taniguchi R, Yatsula B, Furuyama T, Matsumoto T, Komori K, Dardik A. Inhibition of T-Cells by Cyclosporine A Reduces Macrophage Accumulation to Regulate Venous Adaptive Remodeling and Increase Arteriovenous Fistula Maturation. Arteriosclerosis Thrombosis And Vascular Biology 2021, 41: e160-e174. PMID: 33472405, PMCID: PMC7904667, DOI: 10.1161/atvbaha.120.315875.Peer-Reviewed Original ResearchConceptsVascular wall thickeningT helper type 1 (Th1) cellsSuccessful AVF maturationAVF maturationRegulatory T cellsMacrophage accumulationT cellsType 1 cellsArteriovenous fistulaVenous remodelingWall thickeningMouse aortocaval fistula modelT helper type 2T helper type 2 cellsAdaptive remodelingM2 macrophage accumulationPrimary success rateAortocaval fistula modelArteriovenous fistula maturationPreferred vascular accessAnti-inflammatory macrophagesT cell functionWild-type miceEffect of CsAType 2 cells
2020
TGFβ (Transforming Growth Factor-Beta)–Activated Kinase 1 Regulates Arteriovenous Fistula Maturation
Hu H, Lee SR, Bai H, Guo J, Hashimoto T, Isaji T, Guo X, Wang T, Wolf K, Liu S, Ono S, Yatsula B, Dardik A. TGFβ (Transforming Growth Factor-Beta)–Activated Kinase 1 Regulates Arteriovenous Fistula Maturation. Arteriosclerosis Thrombosis And Vascular Biology 2020, 40: e203-e213. PMID: 32460580, PMCID: PMC7316601, DOI: 10.1161/atvbaha.119.313848.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortaArteriovenous Shunt, SurgicalCells, CulturedCollagen Type IEndothelial CellsFibronectinsHumansJNK Mitogen-Activated Protein KinasesMaleMAP Kinase Kinase KinasesMechanotransduction, CellularMice, Inbred C57BLp38 Mitogen-Activated Protein KinasesPhosphorylationStress, MechanicalVascular PatencyVascular RemodelingVena Cava, InferiorConceptsArteriovenous fistulaAVF maturationNoncanonical TGFβSuccessful AVF maturationArteriovenous fistula maturationNovel therapeutic approachesTAK1 functionsFistula maturationHemodialysis accessDeposition of ECMLuminal diameterMouse endothelial cellsMaturation failureTherapeutic approachesLumen dilationControl veinsWall thickeningAVF modelOptimal conduitArterial magnitudesEndothelial cellsTAK1 phosphorylationCollagen 1Growth factorLaminar shear stress
2019
Stimulation of Caveolin-1 Signaling Improves Arteriovenous Fistula Patency
Hashimoto T, Isaji T, Hu H, Yamamoto K, Bai H, Santana JM, Kuo A, Kuwahara G, Foster TR, Hanisch JJ, Yatsula BA, Sessa WC, Hoshina K, Dardik A. Stimulation of Caveolin-1 Signaling Improves Arteriovenous Fistula Patency. Arteriosclerosis Thrombosis And Vascular Biology 2019, 39: 754-764. PMID: 30786746, PMCID: PMC6436985, DOI: 10.1161/atvbaha.119.312417.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAorta, AbdominalArteriovenous Shunt, SurgicalCaveolaeCaveolin 1Cells, CulturedDrug Evaluation, PreclinicalHemorheologyHumansLungMaleMiceMice, Inbred C57BLMice, KnockoutNitric OxideNitric Oxide Synthase Type IIIPeptide FragmentsReceptor, EphB4Signal TransductionVascular RemodelingVena Cava, InferiorConceptsCav-1 KO miceAVF maturationWT miceAVF patencyEph-B4KO miceCav-1 functionCav-1Mouse aortocaval fistula modelEphrin-B2/FcArteriovenous fistula patencyAortocaval fistula modelCaveolin-1 SignalingFistula environmentCav-1 mRNAFistula patencyHET miceVenous adaptationEndothelial cell membraneENOS activityFistula modelRC miceControl veinsWall thickeningMice
2018
Does MR enterography offer added value after a recent CT in the evaluation of abdominal pain in Crohn's disease patients?
Spektor M, Mathur M, Santacana G, Asch D, Huber S, Staib L, Israel G. Does MR enterography offer added value after a recent CT in the evaluation of abdominal pain in Crohn's disease patients? Clinical Imaging 2018, 54: 78-83. PMID: 30562678, DOI: 10.1016/j.clinimag.2018.12.002.Peer-Reviewed Original ResearchConceptsAbdominal painCrohn's diseaseDisease patientsHigher health care costsAcute abdominal painBowel wall thickeningCrohn's disease patientsContrast-enhanced CTStrict inclusion criteriaHealth care costsModerate interobserver agreementRecent CTBowel obstructionConsecutive patientsMR enterographyPatient riskInclusion criteriaBlinded reviewAbdominal radiologistsMRE examinationsCare costsWall thickeningFree fluidRoutine useDiagnostic CT
2015
Sonographic Distinction Between Acute Suppurative Appendicitis and Viral Appendiceal Lymphoid Hyperplasia (“Pink Appendix”) With Pathological Correlation
Sheridan AD, Ehrlich L, Morotti RA, Goodman TR. Sonographic Distinction Between Acute Suppurative Appendicitis and Viral Appendiceal Lymphoid Hyperplasia (“Pink Appendix”) With Pathological Correlation. Ultrasound Quarterly 2015, 31: 95-98. PMID: 25945725, DOI: 10.1097/ruq.0000000000000146.Peer-Reviewed Original ResearchConceptsLymphoid hyperplasiaPathological appearanceAcute suppurative appendicitisAppendiceal wall thickeningDifferent treatment regimensCertain sonographic featuresMerit surgerySuppurative appendicitisPathological findingsTreatment regimensMesenteric lymphadenitisViral etiologyClinicoradiological parametersPathological correlationLymphoid tissueSonographic featuresSonographic appearanceSonographic distinctionWall thickeningHyperplasiaUltrasoundFurther studiesPresent studyAppendicitisRegimensMulticontrast High-Resolution Vessel Wall Magnetic Resonance Imaging and Its Value in Differentiating Intracranial Vasculopathic Processes
Mossa-Basha M, Hwang WD, De Havenon A, Hippe D, Balu N, Becker KJ, Tirschwell DT, Hatsukami T, Anzai Y, Yuan C. Multicontrast High-Resolution Vessel Wall Magnetic Resonance Imaging and Its Value in Differentiating Intracranial Vasculopathic Processes. Stroke 2015, 46: 1567-1573. PMID: 25953365, DOI: 10.1161/strokeaha.115.009037.Peer-Reviewed Original ResearchConceptsReversible cerebral vasoconstriction syndromeVessel wall magnetic resonance imagingCerebral vasoconstriction syndromeMagnetic resonance imagingT2 hyperintensityIntracranial vasculopathyResonance imagingWall thickeningPattern of enhancementCases of atherosclerosisIntracranial vascular diseaseT2 signal characteristicsExcellent inter-reader agreementInter-reader agreementVasculitic lesionsInvasive workupWall involvementStenotic lesionsVasculopathic processPostcontrast enhancementVascular diseaseDifferential diagnosisVasculopathyLesion typeSyndrome
2014
Transient angioedema of small bowel secondary to intravenous iodinated contrast medium
Kulkarni KN, Hegde RG, Balani A, Joshi AR. Transient angioedema of small bowel secondary to intravenous iodinated contrast medium. Indian Journal Of Radiology And Imaging 2014, 24: 303-305. PMID: 25114396, PMCID: PMC4126148, DOI: 10.4103/0971-3026.137065.Peer-Reviewed Original ResearchSmall bowelIntravenous contrast material injectionBowel wall thickeningFavorable clinical outcomeYear old femaleComputed tomography scanContrast material injectionAggressive clinical monitoringClinical outcomesClinical detailsRisk factorsTomography scanIntravenous administrationSpecific treatmentClinical monitoringContrast materialContrast mediumWall thickeningOld femaleMaterial injectionAngioedemaBowelLong segmentDuodenumIleumVein graft adaptation and fistula maturation in the arterial environment
Lu DY, Chen EY, Wong DJ, Yamamoto K, Protack CD, Williams WT, Assi R, Hall MR, Sadaghianloo N, Dardik A. Vein graft adaptation and fistula maturation in the arterial environment. Journal Of Surgical Research 2014, 188: 162-173. PMID: 24582063, PMCID: PMC3972303, DOI: 10.1016/j.jss.2014.01.042.Peer-Reviewed Original ResearchConceptsArteriovenous fistulaVein graftsVein graft adaptationVenous adaptationGraft adaptationArterial environmentCommon surgical procedureAVF maturationDifferent hemodynamic conditionsFistula maturationVenous dilationUnderlying molecular mechanismsIntimal thickeningSurgical proceduresWall thickeningHemodynamic conditions
2007
Correlation of sonographic findings and outcome in necrotizing enterocolitis
Silva CT, Daneman A, Navarro OM, Moore AM, Moineddin R, Gerstle JT, Mittal A, Brindle M, Epelman M. Correlation of sonographic findings and outcome in necrotizing enterocolitis. Pediatric Radiology 2007, 37: 274-282. PMID: 17225155, DOI: 10.1007/s00247-006-0393-x.Peer-Reviewed Original ResearchConceptsPortal venous gasBowel wall echogenicityBowel wall thinningBowel wall thickeningFocal fluid collectionsSonographic findingsVenous gasBowel perfusionIntramural gasFree fluidWall echogenicityFluid collectionWall thickeningAbdominal ultrasonography findingsBowel wall thicknessAUS findingsUltrasonography findingsResultsA totalSurgical interventionAdverse outcomesPeritoneal fluidGroup B.Doppler sonographyGroup A.Group B
2004
Pharmacological Inhibition and Genetic Deficiency of Plasminogen Activator Inhibitor-1 Attenuates Angiotensin II/Salt-Induced Aortic Remodeling
Weisberg AD, Albornoz F, Griffin JP, Crandall DL, Elokdah H, Fogo AB, Vaughan DE, Brown NJ. Pharmacological Inhibition and Genetic Deficiency of Plasminogen Activator Inhibitor-1 Attenuates Angiotensin II/Salt-Induced Aortic Remodeling. Arteriosclerosis Thrombosis And Vascular Biology 2004, 25: 365-371. PMID: 15576638, DOI: 10.1161/01.atv.0000152356.85791.52.Peer-Reviewed Original ResearchMeSH KeywordsAcetatesAdministration, OralAngiotensin IIAnimalsAntigens, DifferentiationAortaAortic DiseasesBlood PressureChemokine CCL2Collagen Type ICollagen Type IIIDrug Evaluation, PreclinicalFibronectinsFibrosisGene Expression RegulationGlomerulosclerosis, Focal SegmentalHeartHypertrophy, Left VentricularIndoleacetic AcidsIndolesKidneyMaleMiceMice, Inbred C57BLMice, KnockoutMyocardiumNephrectomyOsteopontinPlasminogen Activator Inhibitor 1Random AllocationRNA, MessengerSialoglycoproteinsSingle-Blind MethodSodium Chloride, DietaryConceptsAng IIAortic remodelingCardiac fibrosisPAI-039PAI-1 inhibitionVascular remodelingCardiac hypertrophyMouse modelHeart/body weight ratioAng II/saltWall thickeningPharmacological inhibitionSmall molecule PAI-1 inhibitorAortic mRNA expressionHigh salt intakeAortic wall thickeningMale C57BL/6J miceBody weight ratioChemoattractant protein-1PAI-1 deficiencyPAI-1 activityPAI-1 inhibitorPlasminogen activator inhibitorPressor responseAngiotensin II
2001
Serial Motion Assessment by Reference Tracking (SMART): Application to Detection of Local Functional Impact of Chronic Myocardial Ischemia
Pearlman J, Gertz Z, Wu Y, Simons M, Post M. Serial Motion Assessment by Reference Tracking (SMART): Application to Detection of Local Functional Impact of Chronic Myocardial Ischemia. Journal Of Computer Assisted Tomography 2001, 25: 558-562. PMID: 11473185, DOI: 10.1097/00004728-200107000-00008.Peer-Reviewed Original Research
1999
Quantification of regional myocardial wall thickening on electrocardiogram-gated SPECT imaging
Shen M, Liu Y, Sinusas A, Fetterman R, Bruni W, Drozhinin O, Zaret B, Wackers F. Quantification of regional myocardial wall thickening on electrocardiogram-gated SPECT imaging. Journal Of Nuclear Cardiology 1999, 6: 583-595. PMID: 10608585, DOI: 10.1016/s1071-3581(99)90095-8.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsComputer SimulationDiastoleElectrocardiographyHeart VentriclesHumansImage Processing, Computer-AssistedModels, CardiovascularMyocardial InfarctionObserver VariationPhantoms, ImagingPilot ProjectsRadiopharmaceuticalsReproducibility of ResultsSoftwareSystoleTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonVentricular Function, LeftVentricular RemodelingVentriculography, First-PassConceptsPrior myocardial infarctionRegional wall thickeningNormal subjectsMyocardial infarctionWall thickeningNormal wall thickeningPilot studyRegional left ventricular functionLeft ventricular functionAbnormal wall thickeningPercent count increaseECG-gated SPECT imagesSingle photon emissionSPECT imagesCardiac cycleLeft ventricular wallReproducibility of interpretationRegional left ventricular wallPrior infarctionCoronary diseaseVentricular functionValidation studyInfarct areaNormal rangeAnatomic areas
1996
Functional and structural alterations with 24-hour myocardial hibernation and recovery after reperfusion. A pig model of myocardial hibernation.
Chen C, Chen L, Fallon J, Ma L, Li L, Bow L, Knibbs D, McKay R, Gillam L, Waters D. Functional and structural alterations with 24-hour myocardial hibernation and recovery after reperfusion. A pig model of myocardial hibernation. Circulation 1996, 94: 507-16. PMID: 8759096, DOI: 10.1161/01.cir.94.3.507.Peer-Reviewed Original ResearchConceptsRegional coronary flowMyocardial hibernationCoronary flowRegional wall thickeningWall thickeningPig modelShort-term myocardial hibernationRegional lactate productionRate-pressure productCoronary artery stenosisCoronary flow reductionAcute myocardial ischemiaUltrastructural changesLactate productionLocal metabolic changesModerate flow reductionShort-term hibernationRegional oxygen consumptionFlow reductionMyocardium undergoesLAD stenosisArtery stenosisLAD flowMyocardial infarctionStructural alterations
1995
Magnetic resonance mapping demonstrates benefits of VEGF–induced myocardial angiogenesis
Pearlman J, Hibberd M, Chuang M, Harada K, Lopez J, Gladstone S, Friedman M, Sellke F, Simons M. Magnetic resonance mapping demonstrates benefits of VEGF–induced myocardial angiogenesis. Nature Medicine 1995, 1: 1085-1089. PMID: 7489368, DOI: 10.1038/nm1095-1085.Peer-Reviewed Original ResearchConceptsVascular endothelial growth factorMagnetic resonance imagingBlood supplyCoronary occlusive diseasePlacebo-controlled studyCollateral blood supplyBetter ejection fractionCoronary artery occlusionCause of deathCollateral vessel developmentEndothelial growth factorRegional wall thickeningArtery occlusionOcclusive diseaseEjection fractionCollateral vesselsCoronary arteryCollateral developmentIschemic zoneVEGF infusionMyocardial angiogenesisResonance imagingWall thickeningHeart attackPorcine model
1982
Studies in Cutaneous Aging II. The Microvasculature
Braverman I, Fonferko E. Studies in Cutaneous Aging II. The Microvasculature. Journal Of Investigative Dermatology 1982, 78: 444-448. PMID: 7069222, DOI: 10.1111/1523-1747.ep12508027.Peer-Reviewed Original ResearchConceptsVeil cellsBasement membrane-like materialButtock skinVascular wallMicrocirculatory vesselsMembrane-like materialVascular wall thickeningThin-walled vesselsDiabetes mellitusAging IIActinic damagePsoriatic individualsIndividuals 80Chronological agingPostcapillary venulesWall thickeningPeripheral portionVenous capillariesProgressive agingSkinRough endoplasmic reticulumEarly phaseWalled vesselsVesselsCells
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