2019
Stimulation of Caveolin-1 Signaling Improves Arteriovenous Fistula Patency
Hashimoto T, Isaji T, Hu H, Yamamoto K, Bai H, Santana JM, Kuo A, Kuwahara G, Foster TR, Hanisch JJ, Yatsula BA, Sessa WC, Hoshina K, Dardik A. Stimulation of Caveolin-1 Signaling Improves Arteriovenous Fistula Patency. Arteriosclerosis Thrombosis And Vascular Biology 2019, 39: 754-764. PMID: 30786746, PMCID: PMC6436985, DOI: 10.1161/atvbaha.119.312417.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAorta, AbdominalArteriovenous Shunt, SurgicalCaveolaeCaveolin 1Cells, CulturedDrug Evaluation, PreclinicalHemorheologyHumansLungMaleMiceMice, Inbred C57BLMice, KnockoutNitric OxideNitric Oxide Synthase Type IIIPeptide FragmentsReceptor, EphB4Signal TransductionVascular RemodelingVena Cava, InferiorConceptsCav-1 KO miceAVF maturationWT miceAVF patencyEph-B4KO miceCav-1 functionCav-1Mouse aortocaval fistula modelEphrin-B2/FcArteriovenous fistula patencyAortocaval fistula modelCaveolin-1 SignalingFistula environmentCav-1 mRNAFistula patencyHET miceVenous adaptationEndothelial cell membraneENOS activityFistula modelRC miceControl veinsWall thickeningMice
2013
Behavioral and serotonergic response changes in the Dhcr7-HET mouse model of Smith–Lemli–Opitz syndrome
Korade Z, Folkes OM, Harrison FE. Behavioral and serotonergic response changes in the Dhcr7-HET mouse model of Smith–Lemli–Opitz syndrome. Pharmacology Biochemistry And Behavior 2013, 106: 101-108. PMID: 23541496, DOI: 10.1016/j.pbb.2013.03.007.Peer-Reviewed Original ResearchConceptsWild-type control miceMonths of ageControl miceHead-twitch responseSevere behavioral deficitsSocial dominance tube testSmith-LemliOpitz syndromeHET miceSerotonergic systemBehavioral deficitsSpectrum disorderBehavioral disturbancesMouse modelAgonist 1Behavioral testingUnderlying dysfunctionHuman patientsLocomotor activityNew treatmentsCholesterol synthesisMiceMolecular pathophysiologyUnfamiliar mouseDimethoxy-4
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