2025
The Impact of Enhanced Behavioral Health Services on Total Healthcare Costs Among US Employers: A Site-Level Analysis of 19 Cohort Studies
Hawrilenko M, Smolka C, Ward E, Kavelaars R, Brown M, Chekroud A. The Impact of Enhanced Behavioral Health Services on Total Healthcare Costs Among US Employers: A Site-Level Analysis of 19 Cohort Studies. Journal Of Health Economics And Outcomes Research 2025, 12: 246-251. PMID: 40546793, PMCID: PMC12182909, DOI: 10.36469/001c.138634.Peer-Reviewed Original ResearchBehavioral health benefitsComprehensive mental health programMedical spendingMental health programsMental health careBehavioral health servicesHealthcare decision-makingReturn-on-investment estimatesRetrospective matched cohort designMeta-analysisHealth benefitsDifference-in-differences analysisUS employersMatched cohort designMedical claims dataEmployer-sponsored health plansMedication management sessionsHealth programsHealth servicesHealth careHealth plansCohort designInverse varianceDifference-in-differences modelReturn on investmenthe Impact of Enhanced Behavioral Health Services on Total Healthcare Costs Among US Employers: A Site-Level Analysis of 19 Cohort Studies
Hawrilenko M, Smolka C, Ward E, Kavelaars R, Brown M, Chekroud A. he Impact of Enhanced Behavioral Health Services on Total Healthcare Costs Among US Employers: A Site-Level Analysis of 19 Cohort Studies. Journal Of Health Economics And Outcomes Research 2025, 246-251. DOI: 10.36469/jheor.2025.138634.Peer-Reviewed Original ResearchBehavioral health benefitsComprehensive mental health programMedical spendingMental health programsMental health careBehavioral health servicesHealthcare decision-makingReturn-on-investment estimatesRetrospective matched cohort designMeta-analysisHealth benefitsDifference-in-differences analysisUS employersMatched cohort designMedical claims dataEmployer-sponsored health plansMedication management sessionsHealth programsHealth servicesHealth careHealth plansInverse varianceCohort designDifference-in-differences modelReturn on investmentHigh-Deductible Health Plans and Out-of-Pocket Health Care Costs Among Younger Patients With Multiple Myeloma.
Fiala M, Ji M, Slade M, Huber J, Shih Y, Wang M, Colditz G, Wang S, Vij R, Chang S. High-Deductible Health Plans and Out-of-Pocket Health Care Costs Among Younger Patients With Multiple Myeloma. JCO Oncology Practice 2025, op2400978. PMID: 40354593, PMCID: PMC12354019, DOI: 10.1200/op-24-00978.Peer-Reviewed Original ResearchStem-cell transplantationMultiple myelomaTreatment initiationHigh-deductible health plan enrollmentHigh-deductible health plansTransplant receiptShorter time to treatment initiationTime to treatment initiationOOP costsHealth Insurance DatabaseAssociated with delayStatistically significant differenceHealth plansPlan enrolleesOut-of-pocket health care costsYounger patientsOut-of-pocket (OOP) costsCox regressionPrimary outcomeMultivariate analysisSecondary outcomesInsurance databasePatientsTotal health careHealth care costsThe autism phenotype and transdiagnostic dimensional frameworks
Chetcuti L, Spackman E, Frazier T, Whitehouse A, Uljarević M. The autism phenotype and transdiagnostic dimensional frameworks. Developmental Medicine & Child Neurology 2025, 67: 1130-1136. PMID: 40126448, DOI: 10.1111/dmcn.16303.Peer-Reviewed Original ResearchConceptsDiagnostic conceptualizationHierarchical Taxonomy of PsychopathologyHierarchical taxonomyResearch Domain CriteriaTaxonomy of PsychopathologyDiagnostic classification systemsConceptualization of autismAssociated with autismSymptom overlapDimensional alternativesDiagnostic categoriesEmpirical attentionCategorical approachAutismWell-beingIndividual variationResearch findingsPsychopathologyClinical decision-makingHealth plansClinical practiceClinical careComplex clinical conditionsSymptomsResearchTime series data on typhoid fever incidence during outbreaks from 2000 to 2022
Koh D, Duong M, Kipshidze N, Pitzer V, Kim J. Time series data on typhoid fever incidence during outbreaks from 2000 to 2022. Scientific Data 2025, 12: 94. PMID: 39821093, PMCID: PMC11739417, DOI: 10.1038/s41597-024-04289-7.Peer-Reviewed Original ResearchIntegrating artificial intelligence with mechanistic epidemiological modeling: a scoping review of opportunities and challenges
Ye Y, Pandey A, Bawden C, Sumsuzzman D, Rajput R, Shoukat A, Singer B, Moghadas S, Galvani A. Integrating artificial intelligence with mechanistic epidemiological modeling: a scoping review of opportunities and challenges. Nature Communications 2025, 16: 581. PMID: 39794317, PMCID: PMC11724045, DOI: 10.1038/s41467-024-55461-x.Peer-Reviewed Original ResearchConceptsArtificial intelligenceEffective public health planningPublic health planningMechanistic modelSystematic search strategyCapabilities of artificial intelligenceData-mining capabilitiesReview of opportunitiesFusion of AIPotential of AIHealth plansSpectrum of infectious diseasesDisease dynamicsAttributing Racial Differences in Care to Health Plan Performance or Selection
Wallace J, Ndumele C, Lollo A, Macambira D, Lavallee M, Green B, Duchowny K, McWilliams J. Attributing Racial Differences in Care to Health Plan Performance or Selection. JAMA Internal Medicine 2025, 185: 61-72. PMID: 39585673, PMCID: PMC11589859, DOI: 10.1001/jamainternmed.2024.5451.Peer-Reviewed Original ResearchEmergency department visitsPrimary care visitsCross-sectional studyDepartment visitsCare visitsRacial differencesWhite enrolleesMagnitude of racial differencesHealth equity metricHealth care disparitiesWhite Medicaid enrolleesSelection biasSouthern US statesPlanning indicatorsPrescription drug useCare disparitiesSelf-identified blacksHealth plansMain OutcomesEffectiveness of planningPublic reportingAdministrative claimsRandom populationMedicaid populationMedicaid enrollees
2024
Impact of a Community-based Intervention Addressing Loneliness and Health-related Quality of Life (HRQoL) among Seniors
Pinnock C, Shin A, Haugh G, Rothen J, Carlough T, Sylwestrzak G, LaMaster E. Impact of a Community-based Intervention Addressing Loneliness and Health-related Quality of Life (HRQoL) among Seniors. American Journal Of Health Behavior 2024, 48: 68-75. DOI: 10.5993/ajhb.48.4.6.Peer-Reviewed Original ResearchHealth-related quality of lifePatient-reported outcome measuresHealth-related qualityHealthy daysQuality of lifeCommunity-based peer support interventionImproved self-reported outcomesMedicare AdvantagePeer support interventionCommunity-based interventionsPerception of healthSelf-reported outcomesCommunity-based programsCulturally competent interventionsIntervention participantsSupport interventionsHealth behaviorsHealth plansCompetent interventionsHealthcare costsOutcome measuresImproving lonelinessCohort studyLoneliness interventionsLogistic regressionAssociations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study
Zheng X, Pan Y, Qu Y, Ji S, Wang J, Li Z, Zhao F, Wu B, Xie L, Li Y, Song H, Hu X, Qiu Y, Zhang Z, Zhang W, Yang Y, Cai J, Zhu Y, Zhu Y, Cao Z, Ji J, Lv Y, Dai J, Shi X. Associations of Serum Per- and Polyfluoroalkyl Substances with Hyperuricemia in Adults: A Nationwide Cross-Sectional Study. Environmental Science And Technology 2024, 58: 12875-12887. PMID: 38980177, DOI: 10.1021/acs.est.3c11095.Peer-Reviewed Original ResearchNationwide cross-sectional studyPublic health planningCross-sectional studyOdds of hyperuricemiaChinese adultsHealth plansJoint effectsElevated oddsGeneral populationNationwide studyNonmonotonic dose responsePositive associationRisk factorsAdultsHealthEffects of polyfluoroalkyl substancesHealth hazardsParticipantsSerum polyfluoroalkyl substancesJoint effects of PFAS mixtureMeasured serum concentrationsFish consumptionSerum concentrations of uric acidAssociationHyperuricemiaPredicting the Population Risk of Suicide Using Routinely Collected Health Administrative Data in Quebec, Canada: Model-Based Synthetic Estimation Study
Wang J, Kharrat F, Gariépy G, Gagné C, Pelletier J, Massamba V, Lévesque P, Mohammed M, Lesage A. Predicting the Population Risk of Suicide Using Routinely Collected Health Administrative Data in Quebec, Canada: Model-Based Synthetic Estimation Study. JMIR Public Health And Surveillance 2024, 10: e52773. PMID: 38941610, PMCID: PMC11245657, DOI: 10.2196/52773.Peer-Reviewed Original ResearchConceptsHealth administrative dataCommunity-level predictorsRisk prediction modelHealth care systemPopulation riskAdministrative dataHigh-risk regionsHealth systemCare systemIndividual's risk of suicideApplication of risk prediction modelsPopulation health planningHealth administrative databasesSignificant public health issueCase-control study designCommunity-level variablesRisk prediction toolsPublic health issueRisk of suicideSex-specific modelsProportion of suicidesIndividual-level predictorsAdministrative databasesHealth plansSuicide preventionEnrollment in High-Deductible Health Plans and Incident Diabetes Complications
McCoy R, Swarna K, Jiang D, Van Houten H, Chen J, Davis E, Herrin J. Enrollment in High-Deductible Health Plans and Incident Diabetes Complications. JAMA Network Open 2024, 7: e243394. PMID: 38517436, PMCID: PMC10960199, DOI: 10.1001/jamanetworkopen.2024.3394.Peer-Reviewed Original ResearchConceptsHigh-deductible health plansHealth plansChronic disease managementOdds of myocardial infarctionLower-extremity complicationsMixed-effects logistic regression modelsOut-of-pocket costsAssociated with increased oddsDiabetic complicationsInverse propensity score weightingLogistic regression modelsCardiovascular risk factorsEmployer-sponsored health plansDiabetes careRetrospective cohort studyUS adultsPropensity score weightingPotential selection biasMain OutcomesCohort studyBaseline yearIncident complicationsDisease managementMixed-effectsPotential harm
2023
What Difference Does a Health Plan Make? Evidence from Random Plan Assignment in Medicaid.
Geruso M, Layton T, Wallace J. What Difference Does a Health Plan Make? Evidence from Random Plan Assignment in Medicaid. American Economic Journal Applied Economics 2023, 15: 341-379. PMID: 37621701, PMCID: PMC10445793, DOI: 10.1257/app.20210843.Peer-Reviewed Original ResearchEvaluation of High-Deductible Health Plans and Acute Glycemic Complications Among Adults With Diabetes
Jiang D, Herrin J, Van Houten H, McCoy R. Evaluation of High-Deductible Health Plans and Acute Glycemic Complications Among Adults With Diabetes. JAMA Network Open 2023, 6: e2250602. PMID: 36662531, PMCID: PMC9860518, DOI: 10.1001/jamanetworkopen.2022.50602.Peer-Reviewed Original ResearchConceptsHigh-deductible health plansSevere hypoglycemiaED visitsHealth plansCohort studyHDHP enrollmentPotential treatment selection biasAcute diabetes complicationsGlucose-lowering medicationsRetrospective cohort studyOptimal diabetes careAdministrative claims dataTreatment selection biasMixed effects logistic regression modelsLogistic regression modelsGlycemic complicationsGlycemic controlPatient ageDiabetes complicationsDiabetes careHospital visitsStudy populationInverse propensity scoreMAIN OUTCOMEClaims data
2022
898-P: Impact of Switching to a High-Deductible Health Plan on Patients’ Out-of-Pocket Expenditures for Glucose-Lowering Drugs
JIANG D, HERRIN J, VAN HOUTEN H, MCCOY R. 898-P: Impact of Switching to a High-Deductible Health Plan on Patients’ Out-of-Pocket Expenditures for Glucose-Lowering Drugs. Diabetes 2022, 71 DOI: 10.2337/db22-898-p.Peer-Reviewed Original ResearchHigh-deductible health plansGlucose-lowering drugsHDHP enrolleesOOP expensesHealth outcomesPocket expenditureHealth plansBurden of treatmentCostly health conditionsPoor health outcomesDeductible Health PlansGlycemic managementHigh-value careKidney diseaseDiabetes managementOOP costsValue careOOP expenditurePrescription drugsDiabetesHealth conditionsDirect costsDrugsEnrolleesHealth insurance
2021
Impact of the Affordable Care Act on Colorectal Cancer Incidence and Mortality
Lee C, Kushi LH, Reed ME, Eldridge EH, Lee JK, Zhang J, Spiegelman D. Impact of the Affordable Care Act on Colorectal Cancer Incidence and Mortality. American Journal Of Preventive Medicine 2021, 62: 387-394. PMID: 34763959, PMCID: PMC8863627, DOI: 10.1016/j.amepre.2021.08.025.Peer-Reviewed Original ResearchConceptsColorectal cancer-related mortalityColorectal cancer incidenceCancer-related mortalityColorectal cancer outcomesAffordable Care ActCancer incidenceColorectal cancerCancer outcomesCare ActKaiser Permanente Northern California membersHealth plansColorectal cancer screeningInterrupted time series designRace/ethnicityCancer screeningCalifornia membersPreventive servicesPrivate health insurancePocket costsMortalityTime series designIncidenceCost sharingCancerComparison groupComparison of Diabetes Medications Used by Adults With Commercial Insurance vs Medicare Advantage, 2016 to 2019
McCoy RG, Van Houten HK, Deng Y, Mandic PK, Ross JS, Montori VM, Shah ND. Comparison of Diabetes Medications Used by Adults With Commercial Insurance vs Medicare Advantage, 2016 to 2019. JAMA Network Open 2021, 4: e2035792. PMID: 33523188, PMCID: PMC7851726, DOI: 10.1001/jamanetworkopen.2020.35792.Peer-Reviewed Original ResearchConceptsSodium-glucose cotransporter 2 inhibitorsDipeptidyl peptidase-4 inhibitorsCommercial insurance beneficiariesMedicare Advantage beneficiariesDPP-4i treatmentGLP-1RAsType 2 diabetesInsurance beneficiariesMedicare AdvantageGlucose levelsGlucagonlike Peptide-1 Receptor AgonistsPeptide-1 receptor agonistsHealth plansCommercial health insurance plansGLP-1RA treatmentRetrospective cohort studyCotransporter 2 inhibitorsInitiation of treatmentPeptidase-4 inhibitorsLow-income patientsSeparate logistic regression modelsAdministrative claims dataCommercial health plansAdjusted annual rateLogistic regression models
2020
Development of observational rating scales for evaluating patient-centered communication within a whole health approach to care
Wolfe H, Fix G, Bolton R, Ruben M, Bokhour B. Development of observational rating scales for evaluating patient-centered communication within a whole health approach to care. Explore: The Journal Of Science & Healing 2020, 17: 491-497. PMID: 32703684, PMCID: PMC7791595, DOI: 10.1016/j.explore.2020.06.011.Peer-Reviewed Original ResearchConceptsPatient-centered communicationIntegrative health approachesRating ScaleHealth approachWhole healthClinical education programPrimary care clinical encountersHealth measuresHealth plansClinical encountersWhole Health approachPrimary care providersVeterans Health AdministrationPatient-provider interactionsObservational rating scaleUnpaired t-testPatient goalsProvider communicationMAIN OUTCOMECare providersOverall qualityHealth AdministrationClinical settingCohen's dSignificant differencesCohort Profile: The Precipitating Events Project (PEP Study)
Gill T, Han L, Gahbauer EA, Leo-Summers L, Murphy TE. Cohort Profile: The Precipitating Events Project (PEP Study). The Journal Of Nutrition, Health & Aging 2020, 24: 438-444. PMID: 32242212, PMCID: PMC7322244, DOI: 10.1007/s12603-020-1341-4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPrecipitating Events ProjectPEP studyComprehensive home-based assessmentsEpidemiology of disabilityAge 70 yearsHealth care utilizationGreater New HavenLarge health planParticipant-level dataHome-based assessmentEnd of lifeCare utilizationDeath certificatesMedicare claimsDepressive symptomsOngoing longitudinal studyDisabling processEligible membersOlder personsHealth plansLongitudinal studyMethodologic researchCompletion ratesOriginal reportQualified investigators
2019
Graded chronic pain scale revised: mild, bothersome, and high-impact chronic pain.
Von Korff M, DeBar LL, Krebs EE, Kerns RD, Deyo RA, Keefe FJ. Graded chronic pain scale revised: mild, bothersome, and high-impact chronic pain. Pain 2019, 161: 651-661. PMID: 31764390, PMCID: PMC7097879, DOI: 10.1097/j.pain.0000000000001758.Peer-Reviewed Original ResearchConceptsHigh-impact chronic painMild chronic painChronic Pain ScaleGraded Chronic Pain ScaleChronic painPain Scale-RevisedPain scaleLong-term opioid therapySubstantial activity limitationsHealth status indicatorsOpioid therapyAdult enrolleesActivity limitationsPainPain metricsHealth plansNonsignificant differenceStatus indicatorsPersonsValid methodTherapyPrevalenceBothersomeEnrolleesThe Use of a Quasi-Experimental Study on the Mortality Effect of a Heat Wave Warning System in Korea
Heo S, Nori-Sarma A, Lee K, Benmarhnia T, Dominici F, Bell ML. The Use of a Quasi-Experimental Study on the Mortality Effect of a Heat Wave Warning System in Korea. International Journal Of Environmental Research And Public Health 2019, 16: 2245. PMID: 31242672, PMCID: PMC6617315, DOI: 10.3390/ijerph16122245.Peer-Reviewed Original Research
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