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Vishwa Deep Dixit, DVM, PhD

Waldemar Von Zedtwitz Professor of Pathology and Professor of Immunobiology; Director, Yale Center for Research on Aging (Y-Age), Pathology

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Vishwa Deep Dixit, DVM, PhD



Son of teachers, Deep grew up in Hisar (Northwest India). He studied Veterinary Medicine in India, did PhD Research in University of Hannover Germany and postdoc research in Morehouse School of Medicine and NIH. He currently holds Waldemar Von Zedtwitz endowed chair and is a Professor in the Departments of Pathology, Comparative Medicine and Immunobiology. Dixit is also the director of Yale Center for Research on Aging (Y-Age). Dixit lab studies Immunometabolism and aging. His team help establish NLRP3 inflammasome in causing ‘inflammaging’ and immunosenescence that leads to age-related chronic diseases including metabolic dysfunction. Dixit and his collaborators have identified that switch from glycolysis to ketogenesis deactivates the inflammasome and reduces immunopathology. The ongoing work in his laboratory on caloric restriction (CR) in humans (CALERIE-II trial), which extends lifespan in animal models has revealed that adaptation to negative energy balance in a host can be harnessed to identify immunometabolic CR-mimetics to improve health and potentially lifespan. Dixit lab has identified PLA2G7 and SPARC as the CR-inhibited proteins in humans that control inflammation and healthspan in mouse models.

Education & Training

  • Visiting Fellow and Research Fellow
    National Institute on Aging, NIH (2006)
  • PhD
    Haryana Agricultural University (2000)
  • PhD
    Research completed in University of Hannover (2000)
  • MS
    Haryana Agricultural University (1999)
  • DVM
    Haryana Agricultural University (1994)

Honors & Recognition

AwardAwarding OrganizationDate
Nathan W. Shock AwardNational Institute on Aging, National Institutes of Health.2017
Vincent Cristofalo Lecture on GerontologyWistar Institute2017
The Glenn Award for Aging ResearchGlenn Foundation for Medical Research2016
Nathan Shock New Investigator Award for Aging ResearchGerontological Society of America2011
Fellows Award for Research Excellence (FARE 2004, 2005, 2006) by National Institutes of HealthNational Institutes of Health (NIH)2004
Quest Diagnostics – Young Investigator AwardEndocrine Society2004
Nathan Shock Award for Post Doctoral ResearchNational Institute on Aging, NIH2003
1997-2000 German Academic Exchange Service (DAAD) fellowshipDAAD1997

Professional Service

National Institute on Aging, NIHMember, Board of Scientific Counselors. NIA-Intramural Program2017 - Present

Departments & Organizations