Steve W. C. Chang, PhD
Associate Professor TenureDownloadHi-Res Photo
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Associate Professor, Neuroscience
Member, Kavli Institute for Neuroscience
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Appointments
Additional Titles
Associate Professor, Neuroscience
Member, Kavli Institute for Neuroscience
Contact Info
Appointments
Additional Titles
Associate Professor, Neuroscience
Member, Kavli Institute for Neuroscience
Contact Info
About
Titles
Associate Professor Tenure
Associate Professor, Neuroscience; Member, Kavli Institute for Neuroscience
Biography
Steve Chang is an Associate Professor of Psychology and of Neuroscience at Yale University. He is also a member of the Wu Tsai Institute and the Kavli Institute for Neuroscience at Yale. He is the co-Director of Undergraduate Studies of Yale's Neuroscience (NSCI) major. His research aims to understand the neural circuit mechanisms of social cognition and social decision-making. Major research approaches include using naturalistic social interaction paradigms combined with state-of-the-art behavioral and neural technologies. The ultimate goal of the research program is to elucidate the neural mechanisms underlying social cognition and to learn how these processes may be disrupted in psychiatric conditions with social deficits.
Appointments
Department of Psychology
Associate Professor TenurePrimaryChild Study Center
Associate Professor on TermSecondaryNeuroscience
Associate Professor on TermSecondary
Other Departments & Organizations
Education & Training
- Postdoctoral Research Associate
- Duke University (2014)
- PhD
- Washington University in St. Louis, Neurosciences (2009)
- AB
- Washington University in St. Louis, Psychology, magna cum laude (2003)
Research
Overview
Please visit: https://changlab.yale.edu
Medical Research Interests
Amygdala; Neural Networks, Computer; Neural Pathways; Neurophysiology; Prefrontal Cortex; Social Behavior; Social Cognition; Theory of Mind
ORCID
0000-0003-4160-7549- View Lab Website
Chang lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Steve W. C. Chang's published research.
Publications Timeline
A big-picture view of Steve W. C. Chang's research output by year.
Research Interests
Research topics Steve W. C. Chang is interested in exploring.
Anirvan Nandy, PhD
Monika P. Jadi, PhD
Jane Rebecca Taylor, PhD
Philip Corlett, PhD
Praveen Suthaharan
Stephanie Groman, PhD
36Publications
1,930Citations
Social Behavior
Prefrontal Cortex
Amygdala
Neural Pathways
Social Cognition
Neurophysiology
Publications
Featured Publications
Lesions to the mediodorsal thalamus, but not orbitofrontal cortex, enhance volatility beliefs linked to paranoia
Suthaharan P, Thompson S, Rossi-Goldthorpe R, Rudebeck P, Walton M, Chakraborty S, Noonan M, Costa V, Murray E, Mathys C, Groman S, Mitchell A, Taylor J, Corlett P, Chang S. Lesions to the mediodorsal thalamus, but not orbitofrontal cortex, enhance volatility beliefs linked to paranoia. Cell Reports 2024, 43: 114355. PMID: 38870010, PMCID: PMC11231991, DOI: 10.1016/j.celrep.2024.114355.Peer-Reviewed Original ResearchCitationsAltmetricConceptsOrbitofrontal cortexMediodorsal thalamusReward learning rateAssociated with paranoiaExcitotoxic lesionsBrain regionsUnoperated monkeysAction selectionAdaptive behaviorParanoiaBelief updatingMDmcMeaningful changeCortexThalamusBeliefsLearning rateRobust to variabilityCompare performanceRewardBehaviorBrainMonkeysAction policiesPerceptionThe Evolving Landscape of Social Neuroscience and its Implications for Psychiatry
Li S, Kietzman H, Taylor J, Chang S. The Evolving Landscape of Social Neuroscience and its Implications for Psychiatry. Biological Psychiatry 2024 PMID: 38878810, DOI: 10.1016/j.biopsych.2024.06.004.Peer-Reviewed Original ResearchCitationsAltmetricClosed-loop microstimulations of the orbitofrontal cortex during real-life gaze interaction enhance dynamic social attention
Fan S, Dal Monte O, Nair A, Fagan N, Chang S. Closed-loop microstimulations of the orbitofrontal cortex during real-life gaze interaction enhance dynamic social attention. Neuron 2024, 112: 2631-2644.e6. PMID: 38823391, PMCID: PMC11309918, DOI: 10.1016/j.neuron.2024.05.004.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPrimate prefrontal cortexPrefrontal cortexSocial attentionOrbitofrontal cortexDorsomedial prefrontal cortexAnterior cingulate cortexCingulate cortexDirect gazeGaze interactionCortexGaze dynamicsControl different aspectsDistance of fixationDifferent aspectsGaze eventsPartner eyeGazeMultiple regionsMicrostimulationGaze positionAttentionSpatial dimensionsLatencyNeuronsDissociation of vicarious and experienced rewards by coupling frequency within the same neural pathway
Putnam P, Chu C, Fagan N, Dal Monte O, Chang S. Dissociation of vicarious and experienced rewards by coupling frequency within the same neural pathway. Neuron 2023, 111: 2513-2522.e4. PMID: 37348507, PMCID: PMC10527039, DOI: 10.1016/j.neuron.2023.05.020.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsExperienced rewardsVicarious rewardBasolateral amygdalaAlpha/beta frequencyLocal field potentialsSame neural pathwaysSelect brain regionsSocial learningNeural systemsSocial interactionDirectional influenceRewardBrain regionsBeta frequenciesNeural pathwaysGamma frequenciesShared experienceDecision makingNeuronal interactionsSocial agencyField potentialsVoluntary choiceSocial choiceGyrusAmygdalaWidespread implementations of interactive social gaze neurons in the primate prefrontal-amygdala networks
Dal Monte O, Fan S, Fagan NA, Chu CJ, Zhou MB, Putnam PT, Nair AR, Chang SWC. Widespread implementations of interactive social gaze neurons in the primate prefrontal-amygdala networks. Neuron 2022, 110: 2183-2197.e7. PMID: 35545090, PMCID: PMC9262836, DOI: 10.1016/j.neuron.2022.04.013.Peer-Reviewed Original ResearchCitationsAltmetricPrefrontal–amygdala circuits in social decision-making
Gangopadhyay P, Chawla M, Dal Monte O, Chang SWC. Prefrontal–amygdala circuits in social decision-making. Nature Neuroscience 2020, 24: 5-18. PMID: 33169032, PMCID: PMC7899743, DOI: 10.1038/s41593-020-00738-9.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSocial behaviorSystems neuroscience perspectivePrefrontal-amygdala pathwaysPrefrontal-amygdala circuitsPrefrontal cortical regionsSocial cognitionNeuroscience perspectiveNeural basisNeuropeptide oxytocinBrains of primatesNeural mechanismsCortical regionsNon-human primatesSpecific instantiationSocial constructMultiple levelsCognitionNeuronal activityMultiple animal speciesNeurobiologyAmygdalaBehaviorUnderpinningsPrimatesConstructsIs There a ‘Social’ Brain? Implementations and Algorithms
Lockwood PL, Apps MAJ, Chang SWC. Is There a ‘Social’ Brain? Implementations and Algorithms. Trends In Cognitive Sciences 2020, 24: 802-813. PMID: 32736965, PMCID: PMC7501252, DOI: 10.1016/j.tics.2020.06.011.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSocial behaviorNeural processesMotor facultiesInformation processingInfluential frameworkSocial specificitiesAlgorithmic levelGreater integrationPsychologyNeuroscienceBehaviorDifferent levelsImportant new insightsEmpirical approachMarrProcessingFundamental questionsBrainResearchMonkeysFrameworkHumansThe anterior cingulate cortex is necessary for forming prosocial preferences from vicarious reinforcement in monkeys
Basile BM, Schafroth JL, Karaskiewicz CL, Chang SWC, Murray EA. The anterior cingulate cortex is necessary for forming prosocial preferences from vicarious reinforcement in monkeys. PLOS Biology 2020, 18: e3000677. PMID: 32530910, PMCID: PMC7292358, DOI: 10.1371/journal.pbio.3000677.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAnterior cingulate cortexProsocial preferencesVicarious reinforcementCingulate cortexACC lesionsPrimate anterior cingulate cortexSocial preferencesDifferent visual cuesSocial cognitionReward outcomesReinforcement taskReward deliveryVisual cuesACC contributionSocial outcomesCuesSocial relationshipsExcitotoxic lesionsPeripheral targetsGood thingGreater tendencySelfCortexLesion groupSingle neuronsSpecialized medial prefrontal–amygdala coordination in other-regarding decision preference
Dal Monte O, Chu CCJ, Fagan NA, Chang SWC. Specialized medial prefrontal–amygdala coordination in other-regarding decision preference. Nature Neuroscience 2020, 23: 565-574. PMID: 32094970, PMCID: PMC7131896, DOI: 10.1038/s41593-020-0593-y.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMultiple cognitive operationsRostral anterior cingulate gyrusMedial prefrontal cortexSubcortical brain regionsAnterior cingulate gyrusCognitive operationsGamma frequency bandSocial decisionsSpecialized coordinationPrefrontal cortexNegative ORPSocial behaviorNeural populationsCingulate gyrusBrain regionsBasolateral amygdalaNetwork interactDecision preferencesSpecific directionalityNeuronal interactionsRewardGyrusAmygdalaPreferencesCortexThe dorsomedial prefrontal cortex computes task-invariant relative subjective value for self and other
Piva M, Velnoskey K, Jia R, Nair A, Levy I, Chang SW. The dorsomedial prefrontal cortex computes task-invariant relative subjective value for self and other. ELife 2019, 8: e44939. PMID: 31192786, PMCID: PMC6565363, DOI: 10.7554/elife.44939.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRelative subjective valueSubjective valuePrefrontal cortexMulti-voxel pattern analysisVentromedial prefrontal cortexDorsomedial prefrontal cortexNeural correlatesPrefrontal nodesFMRI approachRisky choiceSubjective valuationDmPFCNeural computationSocial attitudesUbiquitous behaviorSelfTaskPattern analysisCortexIndependent tasksBehavioral modelingParticipantsCorrelatesAttitudesDissimilar preferences
Academic Achievements & Community Involvement
honor Kavli Innovative Research Award (PIs: Nandy, Jadi, Chang)
International AwardKavli Institute for NeuroscienceDetails05/01/2019United Stateshonor Early Career Award
International AwardSociety for Social NeuroscienceDetails11/04/2016United Stateshonor Kavli / National Academy of Sciences Frontiers of Science Fellow
International AwardKavli Foundation and National Academy of SciencesDetails08/01/2016United Stateshonor NIMH Biobehavioral Research Award for Innovative New Scientists (BRAINS)
National AwardNIMHDetails07/10/2016United Stateshonor Alfred P. Sloan Research Fellow in Neuroscience
International AwardAlfred P. Sloan FoundationDetails06/01/2015United States
News & Links
Media
News
- June 14, 2024Source: YaleNews
New Insights Into the Brain Regions Involved in Paranoia
- May 31, 2024Source: Yale News
More Than Meets the Eye: Understanding How the Brain Controls Social Gaze
- May 14, 2022Source: YaleNews
When Eyes Meet, Neurons Start to Fire
- May 01, 2017
Combination approach may help combat autism
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