John Carlson, PhD
Eugene Higgins Professor of Molecular, Cellular, and Developmental BiologyDownloadHi-Res Photo
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Contact Info
Molecular, Cellular, and Developmental Biology
Dept. MCDB, Yale University, PO Box 208103
New Haven, Ct 06520-8103
United States
About
Titles
Eugene Higgins Professor of Molecular, Cellular, and Developmental Biology
Appointments
Molecular, Cellular, and Developmental Biology
ProfessorPrimary
Other Departments & Organizations
- Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS)
- Interdepartmental Neuroscience Program
- Kavli Institute for Neuroscience
- Molecular Cell Biology, Genetics and Development
- Molecular, Cellular, and Developmental Biology
- Neuroscience Track
- Wu Tsai Institute
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
Education & Training
- PhD
- Stanford (1982)
- AB
- Harvard (1977)
Research
Overview
Medical Subject Headings (MeSH)
Drosophila; Mosquito Vectors; Smell; Taste
- View Lab Website
Carlson Lab Homepage
Research at a Glance
Yale Co-Authors
Frequent collaborators of John Carlson's published research.
Publications Timeline
A big-picture view of John Carlson's research output by year.
Research Interests
Research topics John Carlson is interested in exploring.
Gaëlle J. S. Talross, PhD
Yichen Luo
Hany Dweck
Lisa Baik, PhD
Shimaa Ebrahim
Brian Weiss, PhD
50Publications
11,125Citations
Publications
2024
Function and evolution of Ir52 receptors in mate detection in Drosophila
Luo Y, Talross G, Carlson J. Function and evolution of Ir52 receptors in mate detection in Drosophila. Current Biology 2024 PMID: 39471807, DOI: 10.1016/j.cub.2024.10.001.Peer-Reviewed Original ResearchAltmetricConceptsMating partnersCluster of genesPotential mating partnersSexually dimorphic neuronsCourtship behaviorEvolutionary timeMate detectionExpression systemFly legFruit flyFly speciesSpeciesBiological problemsTaste neuronsMatingPheromone extractsFliesReceptorsDrosophilaCourtshipGenesNeuronsPheromoneCircuit mappingExpressionMosquito taste responses to human and floral cues guide biting and feeding
Baik L, Talross G, Gray S, Pattisam H, Peterson T, Nidetz J, Hol F, Carlson J. Mosquito taste responses to human and floral cues guide biting and feeding. Nature 2024, 1-8. PMID: 39415007, DOI: 10.1038/s41586-024-08047-y.Peer-Reviewed Original ResearchAltmetricConceptsResponse to sugarFloral cuesCoding capacityControl mosquito vectorsEgg layingTaste sensillaTranscriptome profilingTaste organsNeuronal repertoireBiting behaviorInsect behaviorBitter compoundsInvasive diseaseTaste receptorsTaste systemTasteTaste responsesMosquito vectorsStop signalTaste stimuliFeedingSite waterLabellumExcitatory responsesNectarSugar detection in 3D: Structure of an insect gustatory receptor
Talross G, Carlson J. Sugar detection in 3D: Structure of an insect gustatory receptor. Cell Reports 2024, 43: 114166. PMID: 38691457, DOI: 10.1016/j.celrep.2024.114166.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsExitron splicing of odor receptor genes in Drosophila
Shang X, Talross G, Carlson J. Exitron splicing of odor receptor genes in Drosophila. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2320277121. PMID: 38507450, PMCID: PMC10990081, DOI: 10.1073/pnas.2320277121.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsExitron splicingOdorant receptor genesCases of alternative splicingCanonical open reading framesExpression of odorant receptor genesFunction of olfactory systemReceptor geneProtein-coding exonsOpen reading frameAlternative splicing eventsOlfactory receptor neuronsAlternative polyadenylationReading frameExon-intronEncode proteinsSplicing eventsAlternative splicingNon-coding RNAsStable proteinsPheromone receptorsReceptor neuronsOptogenetic activationPheromone stimulationSplicingNeuronal activity
2023
Diverse mechanisms of taste coding in Drosophila
Dweck H, Carlson J. Diverse mechanisms of taste coding in Drosophila. Science Advances 2023, 9: eadj7032. PMID: 37976361, PMCID: PMC10656072, DOI: 10.1126/sciadv.adj7032.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsThe rich non-coding RNA landscape of the Drosophila antenna
Talross G, Carlson J. The rich non-coding RNA landscape of the Drosophila antenna. Cell Reports 2023, 42: 112482. PMID: 37167060, PMCID: PMC10431215, DOI: 10.1016/j.celrep.2023.112482.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDrosophila antennaPheromone-sensing neuronsLong non-coding RNAsNon-coding RNAsDrosophila olfactory systemRole of lncRNAsMultiple complex behaviorsRNA landscapeOlfactory receptor neuronsNeuronal lncRNAsNeural developmentLncRNAsReceptor neuronsModel systemPheromonal responsesOlfactory systemCritical roleNeuron mapNervous systemRNACombination of lncRNAsSpeciationNeuronsRoleA volatile sex attractant of tsetse flies
Ebrahim S, Dweck H, Weiss B, Carlson J. A volatile sex attractant of tsetse flies. Science 2023, 379: eade1877. PMID: 36795837, PMCID: PMC10204727, DOI: 10.1126/science.ade1877.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Sugar sensation and mechanosensation in the egg-laying preference shift of Drosophila suzukii
Wang W, Dweck H, Talross G, Zaidi A, Gendron J, Carlson J. Sugar sensation and mechanosensation in the egg-laying preference shift of Drosophila suzukii. ELife 2022, 11: e81703. PMID: 36398882, PMCID: PMC9674340, DOI: 10.7554/elife.81703.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsEgg-laying preferenceTaste organsAgricultural pestsDrosophila suzukiiChannel genesStiff substratesDrosophilaTaste sensillaReceptor geneMechanosensory cuesFruit sugarsGenesMechanosensationTaste sensationBitter taste sensationSpeciesEggsSweet taste sensationMajor subsetSuzukiiPestsSugarsElectrophysiological responsesWeak preferenceVariety of changesMeeting a threat of the Anthropocene: Taste avoidance of metal ions by Drosophila
Xiao S, Baik LS, Shang X, Carlson JR. Meeting a threat of the Anthropocene: Taste avoidance of metal ions by Drosophila. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2204238119. PMID: 35700364, PMCID: PMC9231609, DOI: 10.1073/pnas.2204238119.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsGenerations of exposureDipteran speciesAnthropogenic stressorsGR familyEnvironmental changesToxic chemical compoundsBitter-sensing neuronsTaste organsTaste receptorsAvoidance of feedingSugar-sensing neuronsElevated concentrationsZinc ionsDrosophilaChemical compoundsInsectsHuman activitiesBehavioral responsesReceptorsOrganismsFliesSpeciesNeuronsRapid rateDifferent subsetsIr56b is an atypical ionotropic receptor that underlies appetitive salt response in Drosophila
Dweck HKM, Talross GJS, Luo Y, Ebrahim SAM, Carlson JR. Ir56b is an atypical ionotropic receptor that underlies appetitive salt response in Drosophila. Current Biology 2022, 32: 1776-1787.e4. PMID: 35294865, PMCID: PMC9050924, DOI: 10.1016/j.cub.2022.02.063.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSalt tasteBitter-sensing neuronsStop codonLoss of functionNumber of speciesIonotropic receptorsIonotropic receptor familyN-terminal regionReceptor familyNeuronsDrosophila speciesPremature stop codonTaste modalitiesAncient functionGR familySalt responseSense codonsMolecular basisAtypical memberSalt detectionModalitiesCodonSensory modalitiesDrosophilaBehavioral responses
Academic Achievements & Community Involvement
honor Postdoctoral Mentoring Prize, Yale University
Yale University AwardDetails06/02/2023United Stateshonor Byrnes-Sewall Teaching Prize, Yale College
Yale University AwardDetails05/03/2023honor Kornberg-Berg Lifetime Achievement Award in Biomedical Sciences, Stanford Univ.
National AwardDetails10/12/2018honor Max Mozell Award for Outstanding Achievement in the Chemical Senses
National AwardDetails10/12/2018United Stateshonor Member, National Academy of Sciences
UnknownDetails12/31/2012United States
News & Links
News
- October 29, 2024
Noninvasive malaria test could be global game changer
- February 19, 2023Source: YaleNews
Newly Identified Tsetse Fly Pheromone May Help Curb Disease Spread
- February 15, 2023Source: Yale News
Newly identified tsetse fly pheromone may help curb disease spread
- May 01, 2017
Sugar-craving crushed — in flies, at least
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Mailing Address
Molecular, Cellular, and Developmental Biology
Dept. MCDB, Yale University, PO Box 208103
New Haven, Ct 06520-8103
United States