Brisa Palikuqi, PhD

Tissue stem cells hold the great promise of inducing regeneration on demand. Work in our laboratory is focused on the emerging concept that endothelial cells serve as a supportive niche for regeneration. We study the role of blood and lymphatic endothelial cells in the intestine and colon in regenerative processes and gastrointestinal diseases. In parallel, we also work on developing complex human vascularized tissue and organoids to generate novel platforms for precision medicine and offer an avenue for tissue transplantation.

Postdoctoral candidates

We have openings available for postdoctoral fellows with research interests in models of intestinal regeneration and disease, as well as nutrient absorption in the intestine. Candidates with backgrounds in computational biology, immunology, engineering, and metabolomics are strongly encouraged to apply. If you are interested in joining us, please send your CV and a short cover letter to Dr. Palikuqi at brisa.palikuqi@yale.edu. Your CV should include your past academic, professional, and research experiences, along with the names of three potential references. In your cover letter, please provide a brief summary of your PhD research, current research interests, and career goals.

Ph. D. students

We are accepting rotation students! Interested students must be enrolled in a Ph. D. program at Yale University and contact Dr. Palikuqi to discuss.

Medical students

We are looking for medical students

Undergraduate students

We are always looking for talented undergraduate students to join during the year or for summer research! Please contact Dr. Palikuqi to discuss ongoing projects.

Palikuqi, B.*, Rispal, J.*, Reyes, E., Vaka., D., Boffelli, D., Klein, O.^ (2022) “Lymphangiocrine factors are required for proper intestinal recovery after cytotoxic injury” Cell Stem Cell doi:10.1016/j.stem.2022.07.007

Palikuqi, B., Nguyen, D., Li, G., Schreiner, R., Pellegata, A., Liu, Y., Redmond, D., Geng, F., Lin, Y., Gomez-Salinero, J., Yokoyama, M., Zumbo, P., Zhang, T., Kunar, B., Whitherspoon, M., Han, T., Tedeschi, A., Scottoni, F., Lipkin, S., Dow, L., Elemento, O., Xiang, J., Shido, K., Spence, J., Zhou, J., Schwartz, R., DeCoppi, P., Rabbany, S., Rafii, S.^ (2020) “Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis” Nature doi:10.1038/s41586-020-2712-z