Featured Publications
Airway Growth in Preoperative Patients with Crouzon Syndrome
Lu X, Forte AJ, Park KE, Allam O, Smetona J, Alperovich M, Steinbacher DM, Tonello C, Alonso N, Persing JA. Airway Growth in Preoperative Patients with Crouzon Syndrome. Facial Plastic Surgery & Aesthetic Medicine 2021, 23: 191-197. PMID: 33577380, DOI: 10.1089/fpsam.2020.0441.Peer-Reviewed Original ResearchConceptsYears of ageNasal airway volumeAirway volumeCrouzon syndromePharyngeal airwayCross-sectional areaAirway cross-sectional areaObstructive sleep apneaMonths of agePreoperative patientsSleep apneaMaximal constrictionAirway developmentAirway growthTomography scanAge subgroupsCT scanPatientsSyndromeCrouzon patientsNatural historyAgeNormal dimensionsAirwayMaterialise softwareClassification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Classification of Subtypes of Crouzon Syndrome Based on the Type of Vault Suture Synostosis. Journal Of Craniofacial Surgery 2020, 31: 678-684. PMID: 32068731, DOI: 10.1097/scs.0000000000006173.Peer-Reviewed Original ResearchConceptsClass IIICrouzon syndromeClass IClass IISuture involvementSuture synostosisSimilar craniofacial characteristicsComputed tomography scanClassification of subtypesSurgical interventionMorphology of patientsAnatomic deformityTomography scanSurgical techniqueCT scanDifferent subtypesSagittal synostosisSyndromeClass IVPremature closureCraniofacial characteristicsSevere craniofacial malformationsCranial base lengthSynostosisDifferent pathologies
2022
Effect of health care disparities on procedure selection of autologous breast reconstruction in Florida.
Huayllani MT, Torres-Guzman RA, Avila FR, Advani PP, Spaulding AC, Cochuyt JJ, Nguyen MT, Lu X, Rinker BD, Forte AJ. Effect of health care disparities on procedure selection of autologous breast reconstruction in Florida. Breast Disease 2022, 41: 75-80. PMID: 34487016, DOI: 10.3233/bd-210004.Peer-Reviewed Original ResearchConceptsAutologous breast reconstructionBreast reconstructionFree flapFlap reconstructionReconstructive surgeryAutologous breast reconstructive surgeryFlorida Inpatient Discharge DatasetPatients 18 yearsBreast reconstructive surgeryMultivariate logistic regressionPedicled flap reconstructionHealth care disparitiesMann-Whitney testHispanic patientsIndependent associationAutologous reconstructionBreast cancerHigher oddsPatientsCare disparitiesPedicled flapsProcedure selectionLogistic regressionPrivate insuranceFlap
2021
Treatment Contraindications Based on Comorbidity Status in Patients With Melanoma in the United States
Boczar D, Bagaria SP, Spaulding AC, Huayllani MT, Avila FR, Guliyeva G, Lu X, Rinker BD, Forte AJ. Treatment Contraindications Based on Comorbidity Status in Patients With Melanoma in the United States. Anticancer Research 2021, 41: 2067-2070. PMID: 33813415, DOI: 10.21873/anticanres.14976.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseMultivariate logistic regressionComorbid conditionsTreatment contraindicationsGovernment insuranceLogistic regressionUnknown treatment statusMost patientsPatient demographicsComorbidity statusCurative treatmentMelanoma patientsCancer DatabaseIndependent associationOncological patientsMelanoma incidenceTreatment decisionsInclusion criteriaHigher oddsMelanoma treatmentTreatment statusPatientsPoor candidatesPatient treatmentPrivate insuranceConformity of the Virtual Surgical Plan to the Actual Result Comparing Five Craniofacial Procedure Types.
Maniskas S, Pourtaheri N, Chandler L, Lu X, Bruckman KC, Steinbacher DM. Conformity of the Virtual Surgical Plan to the Actual Result Comparing Five Craniofacial Procedure Types. Plastic & Reconstructive Surgery 2021, 147: 915-924. PMID: 33776034, DOI: 10.1097/prs.0000000000007776.Peer-Reviewed Original ResearchConceptsVirtual surgical planningProcedure typeCranial vault remodelingSurgical planningOrthognathic surgeryMandibular distractionVault remodelingMandible reconstructionActual postoperative outcomesVirtual surgical planPostoperative outcomesConsecutive patientsMore predictable resultsSingle surgeonExcellent outcomesTomographic scanSkeletal repositioningPostoperative movementSurgical planBonferroni analysisIntraoperative judgmentIntraoperative guidePermanent implantsPatientsSurgery
2020
Racial Disparity Between Asian and Caucasian Crouzon Syndrome in Skull Morphology.
Lu X, Forte AJ, Fan F, Zhang Z, Teng L, Yang B, Alperovich M, Steinbacher DM, Alonso N, Persing JA. Racial Disparity Between Asian and Caucasian Crouzon Syndrome in Skull Morphology. Journal Of Craniofacial Surgery 2020, 31: 2182-2187. PMID: 33136851, DOI: 10.1097/scs.0000000000006741.Peer-Reviewed Original ResearchConceptsCrouzon patientsCrouzon syndromeLateral pterygoidIntracranial sideRacial disparitiesDifferent patient populationsPosterior fossa volumeCranial basePosterior cranial fossaMiddle cranial baseAsian patientsCaucasian patientsPatient populationTomographic scanPatientsCranial base angleCranial base angulationCranial fossaFossa volumeTreatment planFinite-Element Biomechanical-Simulated Analysis of the Nasolabial Fold.
Chen G, Lu X, Yin N. Finite-Element Biomechanical-Simulated Analysis of the Nasolabial Fold. Journal Of Craniofacial Surgery 2020, 31: 492-496. PMID: 31842067, DOI: 10.1097/scs.0000000000006063.Peer-Reviewed Original ResearchConceptsFinite element analysisFEA modelFEA simulationABAQUS softwareForce loadingComputer-aided design modelEngineering design moduleStudy of deformationBetter biomechanical propertiesHypermesh softwareMaterial propertiesBiomechanical simulationElement typesCAD modelGeomagic StudioDesign moduleBiomechanical modelInteractive application softwareDesign modelBiomechanical propertiesGeometrical resemblanceBiomechanical analysisLoadingSimulationsComputer-AidedNational Analysis of Patients With Ulcerated Melanoma in the United States
Boczar D, Sisti A, Restrepo DJ, Huayllani MT, Manrique OJ, Lu X, Spaulding AC, Bagaria SP, Parker AS, Forte AJ. National Analysis of Patients With Ulcerated Melanoma in the United States. Anticancer Research 2020, 40: 1055-1058. PMID: 32014953, DOI: 10.21873/anticanres.14042.Peer-Reviewed Original ResearchConceptsUlcerated melanomaNational Cancer DatabaseNon-white patientsNon-white raceZip codesYears of agePatient disparitiesPatient demographicsMelanoma patientsTumor characteristicsMale sexUnfavorable prognosisCancer DatabaseHigher oddsLower oddsPatientsMelanomaUlcerationFacility characteristicsLower educationOddsLow incomeEducation levelUrban countiesPresent studyPaget disease of the breast: A national retrospective analysis of the US population
Sisti A, Huayllani MT, Restrepo DJ, Boczar D, Advani P, Lu X, Spaulding AC, Ball CT, McLaughlin SA, Forte AJ. Paget disease of the breast: A national retrospective analysis of the US population. Breast Disease 2020, 39: 119-126. PMID: 32390594, DOI: 10.3233/bd-200439.Peer-Reviewed Original ResearchConceptsNational Cancer DatabasePaget's diseaseComplete mastectomyPartial mastectomyCommon treatmentSurvival rateRegional lymph node metastasisBlack race/ethnicityHigher cancer stageNational retrospective analysisOverall survival rateLymph node metastasisLarger tumor sizeHigh tumor gradeRace/ethnicityMedian ageNode metastasisFemale patientsShorter survivalTumor sizeCancer DatabaseCancer stageTumor gradeTreatment characteristicsMetastatic cancer
2019
What Factors Define Limb Salvage or Amputation Surgery in Osteosarcoma of the Upper Extremities?
Huayllani MT, Restrepo DJ, Boczar D, Sisti A, Spaulding AC, Parker AS, Manrique OJ, Lu X, Wilke BK, Forte AJ. What Factors Define Limb Salvage or Amputation Surgery in Osteosarcoma of the Upper Extremities? Anticancer Research 2019, 39: 6807-6811. PMID: 31810946, DOI: 10.21873/anticanres.13896.Peer-Reviewed Original ResearchConceptsUpper extremityLimb salvageLimb amputationMultivariate logistic regression modelNational Cancer DatabaseStage IV diseaseLogistic regression modelsChi-squared testAmputation surgeryCancer DatabaseInclusion criteriaStage IVPatientsAmputationOsteosarcomaDescriptive studyExtremitiesSurgerySalvageDiseaseRegression modelsStatistical analysisAssociation of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome.
Lu X, Jorge Forte A, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Association of Regional Cranial Base Deformity and Ultimate Structure in Crouzon Syndrome. Plastic & Reconstructive Surgery 2019, 143: 1233e-1243e. PMID: 31136487, DOI: 10.1097/prs.0000000000005643.Peer-Reviewed Original ResearchMandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome.
Lu X, Sawh-Martinez R, Forte AJ, Wu R, Cabrejo R, Wilson A, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Mandibular Spatial Reorientation and Morphological Alteration of Crouzon and Apert Syndrome. Annals Of Plastic Surgery 2019, 83: 568-582. PMID: 31008788, DOI: 10.1097/sap.0000000000001811.Peer-Reviewed Original Research
2018
A Decade's Experience
Lu X, Wang H, You J, Zhang B, Xu Y, Zheng R, Tian L, Fan F. A Decade's Experience. Journal Of Craniofacial Surgery 2018, 29: 2032-2037. PMID: 29927821, DOI: 10.1097/scs.0000000000004695.Peer-Reviewed Original ResearchOrbit, zygoma, and maxilla growth patterns in Crouzon syndrome
Lu X, Forte AJ, Sawh-Martinez R, Wu R, Cabrejo R, Steinbacher DM, Alperovich M, Alonso N, Persing JA. Orbit, zygoma, and maxilla growth patterns in Crouzon syndrome. International Journal Of Oral And Maxillofacial Surgery 2018, 48: 309-321. PMID: 30389113, DOI: 10.1016/j.ijom.2018.10.013.Peer-Reviewed Original ResearchConceptsCrouzon syndromeCT scanAnteroposterior lengthWidth of maxillaPreoperative CT scanMonths-2 yearsMonths of agePrincipal deformityControl subjectsGlobe projectionAge subgroupsMaxillary wideningSecondary deformitiesOrbital wallAnterior protrusionSyndromeFacial malformationsMonthsDeformityAnteroposterior positionZygomatic regionCranial baseZygomaMalformationsMaterialise software