2024
Comprehension of English for‐adverbials: The Nature of Lexical Meanings and the Neurocognitive Architecture of Language
Piñango M, Lai Y, Deo A, Foster‐Hanson E, Lacadie C, Constable T. Comprehension of English for‐adverbials: The Nature of Lexical Meanings and the Neurocognitive Architecture of Language. Topics In Cognitive Science 2024 PMID: 39008778, DOI: 10.1111/tops.12746.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingArchitecture of languageLexical meaningSelf-paced readingConceptual systemNeurocognitive architectureLexical itemsConceptual representationDurative predicatesSyntactic compositionMeaning representationsProcessing profilesActivity patternsMagnetic resonance imagingSentencesConceptual structureResonance imagingIterative readingNeurocognitionLanguageMean compositionReadingComprehensionMeanItemsLow‐calorie diet‐induced weight loss is associated with altered brain connectivity and food desire in obesity
Hoang H, Lacadie C, Hwang J, Lam K, Elshafie A, Rosenberg S, Watt C, Sinha R, Constable R, Savoye M, Seo D, Belfort‐DeAguiar R. Low‐calorie diet‐induced weight loss is associated with altered brain connectivity and food desire in obesity. Obesity 2024, 32: 1362-1372. PMID: 38831482, PMCID: PMC11211061, DOI: 10.1002/oby.24046.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingIntrinsic connectivity distributionDiet-induced weight lossBrain connectivityAssociated with altered brain connectivityLow-calorie dietEating behavior changesShort-term low-calorie dietRight hippocampusTemporal cortexBrain networksWeight lossBrain clustersEffects of diet-induced weight lossGroup differencesFood desireGlucose levelsDiagnosis of type 2 diabetesBehavioral changesMagnetic resonance imagingType 2 diabetesBrainLeptin levelsFood intakeResonance imaging
2023
Impact of postnatal weight gain on brain white matter maturation in very preterm infants
Bobba P, Weber C, Higaki A, Mukherjee P, Scheinost D, Constable R, Ment L, Taylor S, Payabvash S. Impact of postnatal weight gain on brain white matter maturation in very preterm infants. Journal Of Neuroimaging 2023, 33: 991-1002. PMID: 37483073, PMCID: PMC10800683, DOI: 10.1111/jon.13145.Peer-Reviewed Original ResearchConceptsBirth weight z-scoreMagnetic resonance imagingVery preterm infantsPostnatal weight gainWeight z-scoreWhite matter maturationBirth weightDiffusion tensor imagingNeurological outcomePreterm infantsGestational ageWeight gainCorpus callosumHigher birth weight z-scoresBrain white matter maturationLong-term neurological deficitsZ-scoreBrain developmentWeight z-score changeWM tractsZ-score changeWM maturationWeeks of lifeNeurological deficitsNutritional intervention
2019
Chapter 4 The uniqueness of the individual functional connectome
Horien C, Scheinost D, Constable R. Chapter 4 The uniqueness of the individual functional connectome. 2019, 63-81. DOI: 10.1016/b978-0-12-813838-0.00004-2.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingIndividual differencesIndividual functional connectomesBrain functionConnectivity dataGroup-level differencesFunctional connectivity dataHuman neuroimagingBehavioral measuresFunctional connectomeMagnetic resonance imagingResonance imagingInterindividual heterogeneityNext turnConnectomeCognitionBest predictive modelNeuroimagingDifferencesParticipantsDisease
2018
Hyperinsulinemia Invokes Greater Brain Perfusion in Reward and Motivation Regions in Obesity
GROSKREUTZ D, SINHA R, LACADIE C, LAM W, HAMZA M, SCHMIDT C, SEO D, HWANG J, BELFORT-DEAGUIAR R, LEVENTHAL J, ROSENBERG S, PARIKH L, CONSTABLE T, SHERWIN R, JASTREBOFF A. Hyperinsulinemia Invokes Greater Brain Perfusion in Reward and Motivation Regions in Obesity. Diabetes 2018, 67 DOI: 10.2337/db18-365-or.Peer-Reviewed Original ResearchCerebral blood flowElevated insulin levelsInsulin levelsFunctional magnetic resonance imagingLean humansObese humansHour oral glucose tolerance testOral glucose tolerance testSetting of hyperinsulinemiaGlucose tolerance testEuglycemic hyperinsulinemic clampEffect of hyperinsulinemiaAnterior cingulate cortexMagnetic resonance imagingWhole-brain analysisFood-seeking behaviorMiddle temporal gyrusMannKind CorporationCBF responseCNS effectsSatiety factorTolerance testBrain perfusionOB groupLN group
2016
Individual variation in functional brain connectivity: implications for personalized approaches to psychiatric disease
Finn E, Constable R. Individual variation in functional brain connectivity: implications for personalized approaches to psychiatric disease. Dialogues In Clinical Neuroscience 2016, 18: 277-287. PMID: 27757062, PMCID: PMC5067145, DOI: 10.31887/dcns.2016.18.3/efinn.Peer-Reviewed Original ResearchConceptsFunctional brain connectivityFunctional magnetic resonance imagingFunctional brain connectionsBrain connectivityMagnetic resonance imagingFunctional connectivity profilesPsychiatric illnessHealthy subjectsFuture illnessPsychiatric diagnosisPsychiatric diseasesMental illnessResonance imagingSingle-subject levelInterindividual variabilityPersonalized approachFunctional connectivityBrain connectionsIllnessConnectivity profilesRecent evidenceReliable correlateBehavioral phenotypesNeural organizationSubjects
2007
Applications and limitations of whole‐brain MAGIC VASO functional imaging
Scouten A, Constable R. Applications and limitations of whole‐brain MAGIC VASO functional imaging. Magnetic Resonance In Medicine 2007, 58: 306-315. PMID: 17654574, PMCID: PMC2673534, DOI: 10.1002/mrm.21273.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingCerebrospinal fluidBlood Oxygenation Level Dependent (BOLD) imagesAuditory stimulationWhole-brain functional magnetic resonance imagingActivation-induced decreaseCerebral blood volumeMagnetic resonance imagingSuperior temporal gyrusBlood volumeThree-compartment modelResonance imagingCSF contributionTemporal gyrusFunctional imagingVisual stimulation
2005
Disturbed Coupling of rCBF, BOLD and CMRO2 in the Presence of Stimuli During Anesthesia As Revealed by Simultaneous BOLD and CBF Functional Magnetic Resonance Imaging
Qiu M, Ramani R, Shulman R, Hyder F, Rajeevan N, Constable R. Disturbed Coupling of rCBF, BOLD and CMRO2 in the Presence of Stimuli During Anesthesia As Revealed by Simultaneous BOLD and CBF Functional Magnetic Resonance Imaging. Journal Of Neurosurgical Anesthesiology 2005, 17: 224-225. DOI: 10.1097/01.ana.0000187715.47773.67.Peer-Reviewed Original Research
2004
Attentional bias for valenced stimuli as a function of personality in the dot-probe task
Amin Z, Constable R, Canli T. Attentional bias for valenced stimuli as a function of personality in the dot-probe task. Journal Of Research In Personality 2004, 38: 15-23. DOI: 10.1016/j.jrp.2003.09.011.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingAttentional biasAttentional tasksDot-probe taskDimensions of affectFunction of personalityDimensions of personalityValenced stimuliAttentional probeEmotional stimuliNegative affectFusiform gyrusVisual searchGreater activationAutonomic arousalBrain regionsVisual fieldTaskAffectPersonalityIncreased effortStimuliMagnetic resonance imagingBiasNeuroticismEstimation of Anatomical Connectivity by Anisotropic Front Propagation and Diffusion Tensor Imaging
Jackowski M, Kao C, Qiu M, Constable R, Staib L. Estimation of Anatomical Connectivity by Anisotropic Front Propagation and Diffusion Tensor Imaging. Lecture Notes In Computer Science 2004, 3217: 663-670. DOI: 10.1007/978-3-540-30136-3_81.Peer-Reviewed Original ResearchFront arrival timesFront propagationAnisotropic front propagationMagnetic resonance imagingNormal human brainDiffusion tensor imagingDiffusion tensor magnetic resonance imagingAnisotropic versionWhite matterPropagation methodResonance imagingAnatomical connectivityFibrous tissueTensor imagingDiffusion tensorHuman brainSweeping methodArrival timeBrain
2001
Functional MRI of Language Processing: Dependence on Input Modality and Temporal Lobe Epilepsy
Carpentier A, Pugh K, Westerveld M, Studholme C, Skrinjar O, Thompson J, Spencer D, Constable R. Functional MRI of Language Processing: Dependence on Input Modality and Temporal Lobe Epilepsy. Epilepsia 2001, 42: 1241-1254. PMID: 11737158, DOI: 10.1046/j.1528-1157.2001.35500.x.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingAuditory language taskLanguage tasksLanguage processingTask presentationLateralization scoresLanguage comprehension taskVisual language taskModality-specific areasInput modalitiesDifferent input modalitiesMagnetic resonance imagingTemporal lobe epilepsy patientsFMRI resultsBA 44FMRI findingsAuditory inputBroca's areaLanguage areasNeuropsychological testingVisual inputFMRI dataWada testingLanguage localizationAbstract dimensionsPatterns of functional magnetic resonance imaging activation in association with structural lesions in the rolandic region: a classification system.
Carpentier A, Constable R, Schlosser M, de Lotbinière A, Piepmeier J, Spencer D, Awad I. Patterns of functional magnetic resonance imaging activation in association with structural lesions in the rolandic region: a classification system. Journal Of Neurosurgery 2001, 94: 946-54. PMID: 11409524, DOI: 10.3171/jns.2001.94.6.0946.Peer-Reviewed Original ResearchConceptsFMR imaging activationSurgical interventionRolandic regionMotor cortex plasticityMotor task paradigmFunctional magnetic resonance imagingMotor skillsMagnetic resonance imagingSevere motor impairmentFunctional magnetic resonanceFunctional recoveryLesion sideCortical abnormalitiesMotor cortexControl volunteersCortical malformationsStructural lesionsContralateral hemisphereArteriovenous malformationsBrain lesionsSurgical proceduresMotor impairmentPathological lesionsFunctional reorganizationAuthors' institution
2000
Effect of Estrogen on Brain Activation Patterns in Postmenopausal Women During Working Memory Tasks
Shaywitz S, Shaywitz B, Pugh K, Fulbright R, Skudlarski P, Mencl W, Constable R, Naftolin F, Palter S, Marchione K, Katz L, Shankweiler D, Fletcher J, Lacadie C, Keltz M, Gore J. Effect of Estrogen on Brain Activation Patterns in Postmenopausal Women During Working Memory Tasks. Obstetrical & Gynecological Survey 2000, 55: 227-228. DOI: 10.1097/00006254-200004000-00021.Peer-Reviewed Original ResearchBrain activation patternsSuperior frontal gyrusMemory taskFrontal gyrusCognitive functionActivation patternsPronounceable nonsense wordsVerbal memory taskFunctional magnetic resonance imagingWorking Memory TaskRight superior frontal gyrusFunctional magnetic resonanceInferior parietal lobuleVerbal storageNonverbal stimuliNonsense wordsStimulus typeParietal lobuleLeft hemisphereRight hemisphereEffects of estrogenTamil lettersPlacebo conditionMagnetic resonance imagingRetrieval tasks
1997
Predicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification
Pugh K, Shaywitz B, Shaywitz S, Shankweiler D, Katz L, Fletcher J, Skudlarski P, Fulbright R, Constable R, Bronen R, Lacadie C, Gore J. Predicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification. Journal Of Experimental Psychology Human Perception & Performance 1997, 23: 299-318. PMID: 9103996, DOI: 10.1037/0096-1523.23.2.299.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingPhonological effectsLexical decision taskLexical decision latenciesLexical-semantic processesBrain activation patternsWord identificationWord recognitionDecision taskDecision latenciesRegularity effectIndividual differencesFMRI measuresHemispheric lateralizationCerebral basisExperimental paradigmActivation patternsCortical regionsLength effectYoung adultsTaskParticipantsReadingMeasuresMagnetic resonance imagingAn fMRI study of the human cortical motor system response to increasing functional demands
Wexler B, Fulbright R, Lacadie C, Skudlarski P, Kelz M, Constable R, Gore J. An fMRI study of the human cortical motor system response to increasing functional demands. Magnetic Resonance Imaging 1997, 15: 385-396. PMID: 9223039, DOI: 10.1016/s0730-725x(96)00232-9.Peer-Reviewed Original ResearchConceptsMotor-sensory areasSupplementary motor areaFunctional magnetic resonance imagingPremotor areasMotor areaMultiple motor areasComplexity of movementCortical motor systemRight-hand finger movementsIndex finger movementsFinger movementsMagnetic resonance imagingInferior parietal areasConsistent lateralizationResonance imagingBrain regionsActivation changesMotor system responsesParietal areasHand finger movementsPreliminary reproducibility studyFMRI studySignificant main effectWeek periodGreater increase
1995
Functional magnetic resonance imaging of sensory and motor cortex: comparison with electrophysiological localization.
Puce A, Constable R, Luby M, McCarthy G, Nobre A, Spencer D, Gore J, Allison T. Functional magnetic resonance imaging of sensory and motor cortex: comparison with electrophysiological localization. Journal Of Neurosurgery 1995, 83: 262-70. PMID: 7616272, DOI: 10.3171/jns.1995.83.2.0262.Peer-Reviewed Original ResearchConceptsSensorimotor cortexFunctional magnetic resonance imagingMagnetic resonance imagingFunctional MR imagingMotor cortexElectrical stimulationResonance imagingMR imagingUseful noninvasive methodSensory tasksRefractory seizuresMedian nerveAxial gradient echo imagesNormal subjectsSensorimotor areasElectrophysiological localizationFunctional assessmentPrimary sensoryCentral sulcusThenar regionCortexMotor tasksNoninvasive methodGradient-echo imagesPatients