2024
Developmental trajectories of the default mode, frontoparietal, and salience networks from the third trimester through the newborn period
Scheinost D, Chang J, Brennan-Wydra E, Lacadie C, Constable R, Chawarska K, Ment L. Developmental trajectories of the default mode, frontoparietal, and salience networks from the third trimester through the newborn period. Imaging Neuroscience 2024, 2: 1-16. DOI: 10.1162/imag_a_00201.Peer-Reviewed Original ResearchFronto-parietalDevelopmental trajectoriesImpact of maternal mental healthResting-state functional MRIWeeks postmenstrual ageInter-network connectivityIntra-network connectivityMaternal stress levelsMaternal mental healthPostmenstrual ageSalience networkFunctional MRINeurobehavioral disordersNeurodevelopmental disordersDMNMental healthThird trimesterConnectivity measuresSalienceConnectivity values
2020
1994-P: Task-Oriented Connectivity Analysis of Disease-Dependent Effects of Diet
WATT C, STANLEY T, LACADIE C, LAM K, SAVOYE M, SINHA R, CONSTABLE T, SEO D, HWANG J, BELFORT-DEAGUIAR R. 1994-P: Task-Oriented Connectivity Analysis of Disease-Dependent Effects of Diet. Diabetes 2020, 69 DOI: 10.2337/db20-1994-p.Peer-Reviewed Original ResearchMedial hippocampusFunctional MRIFunctional connectivityFood cue taskLow-calorie dietNational InstituteBrain functional connectivityLevel-dependent responsesModulation of emotionSignificant diet effectAnterior amygdalaInferior ponsObese subjectsKidney diseaseGlucose metabolismNeuronal controlMetabolic diseasesNeuronal adaptionBrain regionsBrain connectivityWeight lossDisease statesDiet effectsDietHippocampus
2019
275-LB: Connectome Predictive Modeling May Identify Brain Connectivity Signatures to Help Predict Who Will Benefit from Low-Calorie Diet
GROSKREUTZ D, LAM W, LACADIE C, ELSHAFIE A, HWANG J, SEO D, SAVOYE M, SINHA R, CONSTABLE T, SHERWIN R, BELFORT-DEAGUIAR R. 275-LB: Connectome Predictive Modeling May Identify Brain Connectivity Signatures to Help Predict Who Will Benefit from Low-Calorie Diet. Diabetes 2019, 68 DOI: 10.2337/db19-275-lb.Peer-Reviewed Original ResearchLow-calorie dietCalorie dietWeight lossBrain connectivity matricesEffective weight loss strategyFunctional MRIConnectivity signaturesBrain connectivityWeight loss strategiesReduced calorie dietWeight loss successNon-food imagesMannKind CorporationOB subjectsT2DM subjectsBMI changeLoss strategiesBrain-behavior relationshipsBrain connectivity dataEuglycemiaHyperglycemiaFood picturesDietNational InstituteBOLD activity
2018
Short-Term Weight Loss Undermines Brain Regulation of Food Consumption
LAM W, SEO D, LACADIE C, SCHMIDT C, ROSENBERG S, HOANG H, HWANG J, CONSTABLE T, SAVOYE M, SINHA R, SHERWIN R, BELFORT-DEAGUIAR R. Short-Term Weight Loss Undermines Brain Regulation of Food Consumption. Diabetes 2018, 67 DOI: 10.2337/db18-1802-p.Peer-Reviewed Original ResearchWeight lossTest mealBrain regulationAd libitum test mealShort-term weight lossFunctional MRIBrain activityWeight loss maintenanceTotal calorie intakePost-prandial hyperglycemiaFood consumptionHigh-calorie food picturesMannKind CorporationSuppress appetiteCalorie dietOB subjectsLoss maintenanceObese individualsHyperglycemic clampRegeneron PharmaceuticalsAppetite controlFood intakeCalorie intakeGlaxoSmithKline plcHyperglycemia
2005
Spatial resolution, signal-to-noise ratio, and smoothing in multi-subject functional MRI studies
Scouten A, Papademetris X, Constable R. Spatial resolution, signal-to-noise ratio, and smoothing in multi-subject functional MRI studies. NeuroImage 2005, 30: 787-793. PMID: 16343951, DOI: 10.1016/j.neuroimage.2005.10.022.Peer-Reviewed Original ResearchConceptsSingle-subject studySpecific cortical regionsFunctional MRI studyBasic neuroscience studiesRandom effects analysisNeurosurgical interventionHemodynamic responseMRI studiesCortical activityCortical regionsFunctional MRIBrain functionFunctional anatomyNeurosurgical planningFunctional mappingSubtle activationClinical environmentGroup-level statisticsNeurophysiological underpinningsPartial volume effectsActivationNeuroscience studiesPatientsGroup statistics
2002
Heschl's gyrus identification using functional MRI: neurosurgical issue.
Carpentier A, Clemenceau S, Constable T, Cornu P, Baulac M, Van Effenterre R. Heschl's gyrus identification using functional MRI: neurosurgical issue. Neurochirurgie 2002, 48: 80-6. PMID: 12053161.Peer-Reviewed Original ResearchConceptsAuditory cortex activationFunctional MRIHeschl's gyrusCortex activationPrimary auditory cortex activationPrimary auditory cortexLeft superior temporal regionLanguage areasSuperior temporal regionsEcho-planar sequenceResectable areaPreoperative toolAuditory cortexNeurosurgical issuesHealthy adultsFunctional imagesTemporal regionsGyrusAuditory paradigmRhythmic stimuliFrequent activationSelective activationMRIActivationPlanar sequence
2000
Functional neuroanatomy of executive processes involved in dual-task performance
Adcock R, Constable R, Gore J, Goldman-Rakic P. Functional neuroanatomy of executive processes involved in dual-task performance. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 3567-3572. PMID: 10725387, PMCID: PMC16280, DOI: 10.1073/pnas.97.7.3567.Peer-Reviewed Original ResearchConceptsDual-task paradigmDual-task performanceComponent tasksExecutive systemExecutive processesCentral executive systemSupervisory Attentional SystemAttentional resourcesAttentional systemExecutive functionTask performanceFunctional neuroanatomyMost current modelsSecond taskSubjective experienceFunctional MRIBrain functionTaskContradictory findingsCognitionDual conditionsDistinct systemsParadigmCurrent modelsNeuroanatomy
1999
Brain function in spasmodic dysphonia: A functional MRI study
Kumada M, Mencl E, Pugh K, Constable R, Bell‐Berti F, Honorof D, Gracco V. Brain function in spasmodic dysphonia: A functional MRI study. The Journal Of The Acoustical Society Of America 1999, 105: 1247-1247. DOI: 10.1121/1.425983.Peer-Reviewed Original ResearchSpasmodic dysphoniaSD patientsFunctional MRIPhonation of /a/Functional MRI studyExtrapyramidal systemNormal subjectsMRI studiesVocal cordsVocalis muscleMuscle activityBrain functionDysfunctional regionsVocal foldsPatientsSymptomsDysphoniaSubjectsPhonationRegisterHyperadductionDysfunctionHyperabductionChest registerCord
1996
Activation of Human Prefrontal Cortex during Spatial and Nonspatial Working Memory Tasks Measured by Functional MRI
McCarthy G, Puce A, Constable T, Krystal J, Gore J, Goldman-Rakic P. Activation of Human Prefrontal Cortex during Spatial and Nonspatial Working Memory Tasks Measured by Functional MRI. Cerebral Cortex 1996, 6: 600-611. PMID: 8670685, DOI: 10.1093/cercor/6.4.600.Peer-Reviewed Original ResearchConceptsMiddle frontal gyrusMemory taskPrefrontal cortexHuman prefrontal cortexShape taskFrontal gyrusLeft hemisphereNonspatial working memory tasksSuccessive visual stimuliWorking Memory TaskInferior frontal gyrusTarget detection taskFunctional magnetic resonanceMnemonic contentMnemonic componentsPFC activationMemory domainAreas of activationMemory processesTask onsetVisual stimuliHemispheric activationRight hemisphereDetection taskFunctional MRI
1995
An roc approach for evaluating functional brain mr imaging and postprocessing protocols
Constable R, Skudlarski P, Gore J. An roc approach for evaluating functional brain mr imaging and postprocessing protocols. Magnetic Resonance In Medicine 1995, 34: 57-64. PMID: 7674899, DOI: 10.1002/mrm.1910340110.Peer-Reviewed Original Research