2022
Modeling pandemic to endemic patterns of SARS-CoV-2 transmission using parameters estimated from animal model data
Mullin S, Vander Wyk B, Asher JL, Compton SR, Allore HG, Zeiss CJ. Modeling pandemic to endemic patterns of SARS-CoV-2 transmission using parameters estimated from animal model data. PNAS Nexus 2022, 1: pgac096. PMID: 35799833, PMCID: PMC9254158, DOI: 10.1093/pnasnexus/pgac096.Peer-Reviewed Original ResearchSARS-CoV-2 transmissionNatural infectionDuration of immunitySARS-CoV-2 pandemicAnimal model dataEndemic stateHeterologous vaccinationMedian timeCoronaviral diseaseDeterministic compartmental modelNatural immunityLow prevalenceCoronaviral infectionVaccinationViral transmissionInfectionTransmissible variantsImmunityEndemic patternReinfection dataNatural exposureReinfectionEndemic stabilityVariable durationAnimals
2021
Modeling SARS-CoV-2 propagation using rat coronavirus-associated shedding and transmission
Zeiss CJ, Asher JL, Vander Wyk B, Allore HG, Compton SR. Modeling SARS-CoV-2 propagation using rat coronavirus-associated shedding and transmission. PLOS ONE 2021, 16: e0260038. PMID: 34813610, PMCID: PMC8610237, DOI: 10.1371/journal.pone.0260038.Peer-Reviewed Original ResearchConceptsViral sheddingSialodacryoadenitis virusSARS-CoV-2Prior natural infectionSARS-CoV-2 propagationSeropositive animalsLow-level sheddingNaive recipient ratsCOVID-19Cycle threshold valuesDirect contact exposureSeroconversion ratesReinfected animalsRecipient ratsImmune protectionHigh riskNaive animalsSusceptible individualsInitial infectionGlobal immunityExposure paradigmRat coronavirusNatural infectionInfectionRats
2019
Chapter 13 Viral Disease
Macy J, Compton S. Chapter 13 Viral Disease. 2019, 541-568. PMCID: PMC7153344, DOI: 10.1016/b978-0-12-814338-4.00013-1.Peer-Reviewed Original Research
2017
Murine Astrovirus Infection and Transmission in Neonatal CD1 Mice.
Compton SR, Booth CJ, Macy JD. Murine Astrovirus Infection and Transmission in Neonatal CD1 Mice. Journal Of The American Association For Laboratory Animal Science 2017, 56: 402-411. PMID: 28724490, PMCID: PMC5517330.Peer-Reviewed Original Research
2012
Transmission of mouse parvovirus to neonatal mice.
Compton SR, Paturzo FX, Macy JD. Transmission of mouse parvovirus to neonatal mice. Journal Of The American Association For Laboratory Animal Science 2012, 51: 797-802. PMID: 23294886, PMCID: PMC3508184.Peer-Reviewed Original Research
1998
Interactions of Enterotropic Mouse Hepatitis Viruses with Bgp2 Receptor Proteins
Compton S. Interactions of Enterotropic Mouse Hepatitis Viruses with Bgp2 Receptor Proteins. Advances In Experimental Medicine And Biology 1998, 440: 25-31. PMID: 9782261, DOI: 10.1007/978-1-4615-5331-1_4.Peer-Reviewed Original ResearchConceptsCMT93 cellsReceptor geneEnterotropic mouse hepatitis virus infectionMouse hepatitis virus infectionHepatitis virus infectionMHV-A59 infectionLimited tissue tropismCell receptor interactionsMHV infectionNeonatal miceVirus infectionIntestinal mucosaReceptor mRNAMouse hepatitisBHK cellsReceptor isoformsUnidentified receptorInfectionMonoclonal antibodiesTissue tropismVero cellsReceptor interactionRI useReceptor proteinReceptors
1995
Multiple Receptor-Dependent Steps Determine the Species Specificity of HCV-229E Infection
Levis R, Cardellichio C, Scanga C, Compton S, Holmes K. Multiple Receptor-Dependent Steps Determine the Species Specificity of HCV-229E Infection. Advances In Experimental Medicine And Biology 1995, 380: 337-343. PMID: 8830504, DOI: 10.1007/978-1-4615-1899-0_55.Peer-Reviewed Original ResearchConceptsHuman aminopeptidase NSpecies specificityBrush border membraneCell linesVirus bindingHCV-229EHuman cellsAminopeptidase NCellular receptorsHCV 229E.SpeciesCell sortingIntestinal brush border membraneHuman coronavirus 229EAnimal coronavirusesBindsMembraneVirus penetrationCellsVirus yieldBorder membraneViral spikeCoronavirus 229EBindingInfectionCoronavirus Receptors
Holmes K, Compton S. Coronavirus Receptors. The Viruses 1995, 55-71. DOI: 10.1007/978-1-4899-1531-3_4.Peer-Reviewed Original Research
1994
Enterotropic Strains of Mouse Coronavirus Differ in Their Use of Murine Carcinoembryonic Antigen-Related Glycoprotein Receptors
Compton S. Enterotropic Strains of Mouse Coronavirus Differ in Their Use of Murine Carcinoembryonic Antigen-Related Glycoprotein Receptors. Virology 1994, 203: 197-201. PMID: 8030279, PMCID: PMC7131022, DOI: 10.1006/viro.1994.1475.Peer-Reviewed Original ResearchConceptsSJL miceLimited tissue tropismMHV-RIEnterotropic mouse hepatitis virusBALB/c miceTissue tropismMonoclonal antibody CC1BALB/cMouse hepatitis virusRole of receptorsMurine carcinoembryonic antigenC miceEnterotropic strainsHepatitis virusCarcinoembryonic antigenBHK cellsInfectionMiceDifferent receptorsReceptorsCell linesGlycoprotein receptorsMurine tissuesMouse coronavirusMHV
1990
Is the 110K Glycoprotein the Only Receptor for MHV and Does Its Expression Determine Species Specificity?
Holmes K, Williams R, Cardellichio C, Compton S, Stephensen C, Snyder S, Frana M, Jiang G, Smith A, Knobler R. Is the 110K Glycoprotein the Only Receptor for MHV and Does Its Expression Determine Species Specificity? Advances In Experimental Medicine And Biology 1990, 276: 37-44. PMID: 1966425, DOI: 10.1007/978-1-4684-5823-7_6.Peer-Reviewed Original ResearchConceptsSJL/J miceNormal target tissuesJ miceMHV-A59BALB/c miceTarget tissuesVirus overlay protein blot assaySJL/JMouse hepatitis virusSusceptible miceBinding of virionsC miceHepatitis virusOnly receptorBlot assaysVirus bindingMiceTissue tropismIntestine membranesMurine virusesHepatocyte membraneProtein blot assayVirusInfectionMolecular mechanisms