2021
Neurological Aging and Pharmacological Management of Geriatric Patients
Akhtar S. Neurological Aging and Pharmacological Management of Geriatric Patients. Current Anesthesiology Reports 2021, 11: 381-386. DOI: 10.1007/s40140-021-00497-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2018
Pharmacological considerations in the elderly
Akhtar S. Pharmacological considerations in the elderly. Current Opinion In Anaesthesiology 2018, 31: 11-18. PMID: 29189287, DOI: 10.1097/aco.0000000000000544.Peer-Reviewed Original ResearchConceptsAnesthetic drugsNeurophysiological changesPoor perioperative outcomesCurrent practice patternsLarge database studiesDepth of anesthesiaIntraoperative hypotensionPerioperative outcomesElderly patientsAnesthetic medicationsDose adjustmentCNS depressionGeriatric patientsPractice patternsDrug managementPharmacologic studiesReceptor levelsPharmacological considerationsCurrent recommendationsDatabase studyElderly populationFunctional connectivityAnesthetic dosingHypotensionDrugs
2015
Geriatric Pharmacology
Akhtar S, Ramani R. Geriatric Pharmacology. Anesthesiology Clinics 2015, 33: 457-469. PMID: 26315631, DOI: 10.1016/j.anclin.2015.05.004.Peer-Reviewed Original ResearchConceptsElderly patientsLong-term outcomesEnd-organ sensitivityFurther pharmacologic studiesOlder patientsAnesthetic medicationsGeriatric pharmacologyPharmacologic studiesAnesthetic drugsPatientsDrug overdosingDecreased volumePhysiologic processesContinuous variablesTrue extentMedicationsAnesthetics