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Venkata Boddupalli, PhD

Assistant Professor Adjunct
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Contact Info

Yale School of Medicine

Department of Medicine (Digestive Diseases), PO Box 208019

New Haven, CT 06520-8019

United States

About

Titles

Assistant Professor Adjunct

Biography

I have worked for past 10 years understating mechanisms that regulate tissue resident immune cell homeostasis. In my PhD and postdoctoral research, I have studied underlying principles that govern homeostasis of Dendritic cells, Hematopoietic Stem Cells (HSCs), Tissue Resident Memory T cells (TRM) and NK cells. I did my PhD at University of Bern, Switzerland with Prof. Markus Manz. My doctoral research work revealed T cells as a source of Flt3L, facilitating DC maintenance in lymphoid tissues also we identified hemostatic mechanisms employed by long term self-renewing HSCs in mice. At Yale Cancer Center under the guidance of Prof. Madhav Dhodapkar and Prof. Susan Kaech my research focused on defining features of TRM cells using mouse models and studying their role in solid tumors. More recently under with Dr.Tamar Taddei and Prof. Pramod Mistry we are studying dysregulation of TRM cells in liver cancers patients and in conditions of biliary inflammation. I am also working on understanding the role brain infiltrated immune cells and resident microglia in mediating neuro-immune inflammation using neuronapathic Gaucher diseases (nGD) mouse models. My long-term research goals are identifying specific tissue cues that are important for immune surveillance in Brain and Liver.

Appointments

Other Departments & Organizations

Education & Training

PhD
Bern University, Immunology (2010)
MS
Bharathidasan University, Biotechnology (2001)
BS
Nagarjuna University, Biochemistry (1999)

Research

Overview

Medical Subject Headings (MeSH)

Immune System Diseases; Liver Diseases; Parkinson Disease

Academic Achievements & Community Involvement

  • activity

    Frontiers Hematology

  • activity

    Frontiers Oncology

  • activity

    Yale Journal of Biology and Medicine

  • honor

    New Investigator Award in Clinical/Translational Science

Get In Touch

Contacts

Mailing Address

Yale School of Medicine

Department of Medicine (Digestive Diseases), PO Box 208019

New Haven, CT 06520-8019

United States