2023
Cognitive behavioral therapy following esketamine for major depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol
Kitay B, Murphy E, Macaluso M, Corlett P, Hershenberg R, Joormann J, Martinez-Kaigi V, Nikayin S, Rhee T, Sanacora G, Shelton R, Thase M, Wilkinson S. Cognitive behavioral therapy following esketamine for major depression and suicidal ideation for relapse prevention: The CBT-ENDURE randomized clinical trial study protocol. Psychiatry Research 2023, 330: 115585. PMID: 37935086, DOI: 10.1016/j.psychres.2023.115585.Peer-Reviewed Original ResearchMeSH KeywordsCognitive Behavioral TherapyDepressionDepressive Disorder, MajorHumansRandomized Controlled Trials as TopicSuicidal IdeationConceptsCognitive behavioral therapyMajor depressionSuicidal ideationRelapse preventionBehavioral therapyStudy protocolHigh riskClinical trial study protocolLong-term treatment approachKey secondary outcomesTrial study protocolHigh relapse rateHigh-risk populationSignificant suicidal ideationHospital dischargeSecondary outcomesPrimary outcomeRelapse rateFeasibility trialEsketamineTreatment approachesPatientsSuicide attemptsTherapySupplemental indicationsThe Role of Psychotherapy in the Management of Treatment-Resistant Depression
Rogan T, Wilkinson S. The Role of Psychotherapy in the Management of Treatment-Resistant Depression. Psychiatric Clinics Of North America 2023, 46: 349-358. PMID: 37149349, DOI: 10.1016/j.psc.2023.02.006.Peer-Reviewed Original ResearchMeSH KeywordsAntidepressive AgentsCognitive Behavioral TherapyDepressionDepressive Disorder, Treatment-ResistantHumansPsychotherapyConceptsTreatment-resistant depressionRole of psychotherapySomatic therapiesLong-term outcomesPositive therapeutic benefitsPsychotherapy modalitiesRandomized trialsMood disordersTherapeutic benefitNeural plasticityTherapyMore trialsForms of psychotherapyTrialsDepressionLess evidenceModalitiesPsychotherapy approachesPsychotherapyPotential combinations
2017
Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression
Wilkinson ST, Wright D, Fasula MK, Fenton L, Griepp M, Ostroff RB, Sanacora G. Cognitive Behavior Therapy May Sustain Antidepressant Effects of Intravenous Ketamine in Treatment-Resistant Depression. Psychotherapy And Psychosomatics 2017, 86: 162-167. PMID: 28490030, PMCID: PMC5516265, DOI: 10.1159/000457960.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAdultAntidepressive AgentsCognitionCognitive Behavioral TherapyCombined Modality TherapyDepressive Disorder, MajorDepressive Disorder, Treatment-ResistantFemaleHumansKaplan-Meier EstimateKetamineMaleMiddle AgedPsychiatric Status Rating ScalesRecurrenceRemission InductionTreatment OutcomeYoung AdultConceptsTreatment-resistant depressionCognitive behavioral therapyAntidepressant effectsKetamine's antidepressant effectsKetamine exposureIntravenous ketamineKetamine infusion therapyWeeks of protocolOpen-label trialLong-term treatmentStandardized clinical protocolCognitive behavior therapyKetamine nonrespondersKetamine respondersRelapse rateMedian timeInfusion therapyClinical protocolsKetamineNeurobiological changesRemissionBehavioral therapyTherapyWeeksBehavior therapyComputer-Assisted Cognitive Behavior Therapy to Prevent Relapse Following Electroconvulsive Therapy
Wilkinson ST, Ostroff RB, Sanacora G. Computer-Assisted Cognitive Behavior Therapy to Prevent Relapse Following Electroconvulsive Therapy. Journal Of Ect 2017, 33: 52-57. PMID: 27564424, PMCID: PMC5315599, DOI: 10.1097/yct.0000000000000348.Peer-Reviewed Original ResearchConceptsComputer-assisted cognitive-behavior therapyElectroconvulsive therapyCognitive behavior therapyMean timeOpen-label trialMajor depressive episodeMean numberBehavior therapyAcute treatmentDepressive episodeIndex coursePrevent relapseDepression severityRelapsePotential efficacyTherapyMonthsOwn homesPreliminary evidenceRemittersTrialsSubjectsEntire sampleHoursRemission