A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression
Oikonomou E, Holste G, Yuan N, Coppi A, McNamara R, Haynes N, Vora A, Velazquez E, Li F, Menon V, Kapadia S, Gill T, Nadkarni G, Krumholz H, Wang Z, Ouyang D, Khera R. A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression. JAMA Cardiology 2024, 9: 534-544. PMID: 38581644, PMCID: PMC10999005, DOI: 10.1001/jamacardio.2024.0595.Peer-Reviewed Original ResearchCardiac magnetic resonanceAortic valve replacementCardiac magnetic resonance imagingAV VmaxSevere ASAortic stenosisCohort studyPeak aortic valve velocityCohort study of patientsAortic valve velocityCohort of patientsTraditional cardiovascular risk factorsAssociated with faster progressionStudy of patientsCedars-Sinai Medical CenterAssociated with AS developmentCardiovascular risk factorsCardiovascular imaging modalitiesIndependent of ageModerate ASEjection fractionEchocardiographic studiesValve replacementRisk stratificationCardiac structureHigh- versus low-gradient aortic stenosis: Is our evaluation limited by aorto-mitral angle on cardiovascular CT?
See C, Kim Y, Park J, Wang Y, Reinhardt S, Shkolnik E, Faridi K, Lombo B, Bellumkonda L, McNamara R, Sugeng L, Hur D. High- versus low-gradient aortic stenosis: Is our evaluation limited by aorto-mitral angle on cardiovascular CT? International Journal Of Cardiology 2024, 409: 132174. PMID: 38754590, DOI: 10.1016/j.ijcard.2024.132174.Peer-Reviewed Original ResearchNormal-flow low-gradientAortic valve areaTranscatheter AV replacementParadoxical low-flow low-gradientCardiovascular CTTransthoracic echocardiogramCalcium scoreAS patientsDiagnosis of severe ASLow-gradient aortic stenosisHG-AS patientsLG-AS patientsLow-flow low-gradientAorto-mitral angleAortic valve (AV) stenosisLG-ASPLFLG-ASAV replacementSevere ASConsecutive patientsAortic stenosisValve areaAS phenotypeClinical managementEchocardiogram