2024
Harnessing Natural Language Processing to Assess Quality of End-of-Life Care for Children With Cancer
Lindsay M, de Oliveira S, Sciacca K, Lindvall C, Ananth P. Harnessing Natural Language Processing to Assess Quality of End-of-Life Care for Children With Cancer. JCO Clinical Cancer Informatics 2024, 8: e2400134. PMID: 39265122, PMCID: PMC11407740, DOI: 10.1200/cci.24.00134.Peer-Reviewed Original ResearchConceptsEnd-of-life carePalliative care consultationGoals of careLocation of deathProportion of decedentsDocumented discussionCare consultationEvidence-based quality measuresMeasure quality of careGold standard manual chart reviewQuality measuresQuality of careEnd of lifeContent of clinical notesLife-sustaining treatmentEnd-of-lifeManual chart reviewCancer decedentsEfficient quality measureCohort of childrenAssess qualityMulti-center researchQuality improvementMeasure qualityCare
2023
Measuring Pediatric Palliative Care Quality: Challenges and Opportunities
Boyden J, Bogetz J, Johnston E, Thienprayoon R, Williams C, McNeil M, Patneaude A, Widger K, Rosenberg A, Ananth P. Measuring Pediatric Palliative Care Quality: Challenges and Opportunities. Journal Of Pain And Symptom Management 2023, 65: e483-e495. PMID: 36736860, PMCID: PMC10106436, DOI: 10.1016/j.jpainsymman.2023.01.021.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsChildHealth PolicyHospice and Palliative Care NursingHumansPalliative CareQuality of Health Care
2022
Development of Primary Palliative Care End-of-Life Quality Measures: A Modified Delphi Process.
Bogetz J, Johnston E, Thienprayoon R, Patneaude A, Ananth P, Rosenberg A. Development of Primary Palliative Care End-of-Life Quality Measures: A Modified Delphi Process. Pediatrics 2022, 150 PMID: 36437228, DOI: 10.1542/peds.2022-058241.Peer-Reviewed Original ResearchMeSH KeywordsAdultChildHospitalsHumansPalliative CareQuality of Health CareQuality of LifeTerminal CareConceptsComplex chronic conditionsEOL quality measuresPediatric palliative careEnd of lifeElectronic health recordsHealth care utilizationMultidisciplinary expert panelHigh-quality pediatric palliative careManual chart reviewQuality improvement initiativesModified Delphi processChart reviewCare utilizationSymptom managementPalliative careChronic conditionsIllness trajectoryPediatric measuresLife quality measuresDelphi processHealth recordsExpert panelImprovement initiativesQuality measuresInterprofessional servicesEnd‐of‐life care quality for children with cancer who receive palliative care
Ananth P, Lindsay M, Nye R, Mun S, Feudtner C, Wolfe J. End‐of‐life care quality for children with cancer who receive palliative care. Pediatric Blood & Cancer 2022, 69: e29841. PMID: 35686746, PMCID: PMC10498672, DOI: 10.1002/pbc.29841.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionLife care qualityDistressing symptomsCancer decedentsEnd of lifeUnit admissionMechanical ventilationCare qualityPalliative Care DatabaseDays of lifeLower household incomeAnnual household incomeHospice enrollmentHospital admissionMultivariable analysisPatient factorsUnivariable analysisPalliative careCare databaseHospice servicesLower oddsResearch DatabaseCancer typesHospital servicesSurvey of Pediatric Palliative Care Quality Improvement Training, Activities, and Barriers
Bogetz JF, Johnston E, Ananth P, Patneaude A, Workgroup T, Thienprayoon R, Rosenberg A. Survey of Pediatric Palliative Care Quality Improvement Training, Activities, and Barriers. Journal Of Pain And Symptom Management 2022, 64: e123-e131. PMID: 35577143, DOI: 10.1016/j.jpainsymman.2022.04.182.Peer-Reviewed Original ResearchConceptsPediatric palliative careQI activitiesHigh-quality pediatric palliative careQI effortsQI workPediatrics Task ForceHalf of participantsQuality improvement activitiesPalliative careQuality improvement trainingEducation/trainingSerious illnessImprovement NetworkElectronic surveyQI trainingOne-thirdHours totalTwo-thirdsCliniciansClinical disciplinesOne-quarterResearch NetworkTask ForceDedicated staffStandardized measures
2021
Perspectives of pediatric oncologists and palliative care physicians on the therapeutic use of cannabis in children with cancer
Oberoi S, Protudjer JLP, Rapoport A, Rassekh SR, Crooks B, Siden H, Decker K, Ananth P, Chapman S, Balneaves LG, Vanan MI, Kelly LE. Perspectives of pediatric oncologists and palliative care physicians on the therapeutic use of cannabis in children with cancer. Cancer Reports 2021, 5: e1551. PMID: 34672127, PMCID: PMC9458513, DOI: 10.1002/cnr2.1551.Peer-Reviewed Original ResearchMeSH KeywordsCannabisChildCross-Sectional StudiesHumansNeoplasmsOncologistsPalliative CarePhysiciansConceptsPalliative care physiciansCare physiciansPediatric oncologistsCannabis-related researchPediatric oncology patientsManagement of nauseaMost pediatric oncologistsSafety of cannabisPotential roleUse of cannabisSymptom controlPoor appetiteSymptom reliefChronic painOncology patientsPediatric oncologySide effectsMedical cannabisOncologistsTherapeutic useAnticancer effectsPhysiciansCancerSurvey domainsCannabisSociodemographic and hospital‐based predictors of intense end‐of‐life care among children, adolescents, and young adults with hematologic malignancies
Mun S, Wang R, Ma X, Ananth P. Sociodemographic and hospital‐based predictors of intense end‐of‐life care among children, adolescents, and young adults with hematologic malignancies. Cancer 2021, 127: 3817-3824. PMID: 34185881, PMCID: PMC8478813, DOI: 10.1002/cncr.33764.Peer-Reviewed Original ResearchConceptsHematologic malignanciesYoung adultsLife careMultivariable logistic regression modelCancer-directed treatmentPremier Healthcare DatabaseRetrospective cohort studyEmergency department visitsIntensive care unitHigh-intensity endDays of lifeMajority of childrenLogistic regression modelsIntravenous chemotherapyTracheostomy placementCohort studyDepartment visitsCare unitMechanical ventilationHospital characteristicsMultivariable modelCardiopulmonary resuscitationType of insuranceHealthcare databasesMalignancyA Stakeholder-Driven Qualitative Study to Define High Quality End-of-Life Care for Children With Cancer
Ananth P, Mun S, Reffat N, Li R, Sedghi T, Avery M, Snaman J, Gross CP, Ma X, Wolfe J. A Stakeholder-Driven Qualitative Study to Define High Quality End-of-Life Care for Children With Cancer. Journal Of Pain And Symptom Management 2021, 62: 492-502. PMID: 33556497, PMCID: PMC8339188, DOI: 10.1016/j.jpainsymman.2021.01.134.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildHospice CareHumansNeoplasmsPalliative CareQualitative ResearchTerminal CareYoung AdultConceptsHigh-quality endQuality EOLCAdvanced cancerSymptom managementLife careQuality endLocation of deathMulticenter qualitative studyAvoidance of hospitalizationPerson-centered measuresCancer stakeholdersEnd of lifeSupportive careMechanical ventilationParents of childrenEmergency departmentInterdisciplinary careInterdisciplinary healthcare professionalsCardiopulmonary resuscitationHospice careQualitative studyCancerHealthcare professionalsFamily preferencesYoung adults
2020
Patterns of medication use at end of life by pediatric inpatients with cancer
Prozora S, Shabanova V, Ananth P, Pashankar F, Kupfer GM, Massaro SA, Davidoff AJ. Patterns of medication use at end of life by pediatric inpatients with cancer. Pediatric Blood & Cancer 2020, 68: e28837. PMID: 33306281, DOI: 10.1002/pbc.28837.Peer-Reviewed Original ResearchConceptsMedication usePediatric inpatientsVizient Clinical Database/Resource ManagerHematopoietic stem cell transplantLife-sustaining medicationsMedication utilization patternsSymptom management medicationsUse of opioidsStem cell transplantIntensive care unitLength of stayAcademic medical centerResource use dataLast weekWarrants further studyEvidence-based approachVasopressor useEnd of lifeCare unitCell transplantMedication categoriesResuscitate statusRetrospective studyMalignancy typeOdds ratioParent Perceptions of Team-Delivered Care for Children With Advanced Cancer: A Report From the PediQUEST Study
Feraco AM, Ananth P, Dussel V, Al-Sayegh H, Ma C, Rosenberg AR, Feudtner C, Wolfe J. Parent Perceptions of Team-Delivered Care for Children With Advanced Cancer: A Report From the PediQUEST Study. Journal Of Pain And Symptom Management 2020, 60: 811-817. PMID: 32450115, PMCID: PMC7508972, DOI: 10.1016/j.jpainsymman.2020.05.019.Peer-Reviewed Original ResearchMeSH KeywordsChildCross-Sectional StudiesHumansNeoplasmsPalliative CarePerceptionQuality of Health CareSurveys and QuestionnairesConceptsAdvanced cancerCare teamIndividual cliniciansExact testCare qualityRatings of careFisher's exact testHealth care teamSymptom management trialsParents' perceptionsChildhood cancer careCross-sectional surveyOne-third reportInterprofessional health care teamsCare of childrenClinician typePediQUEST studyPrimary outcomeParents of childrenCancer careAssociated FactorsRefractory cancerChild's oncologistExcellent careCancer
2017
Trends in Hospital Utilization and Costs among Pediatric Palliative Care Recipients
Ananth P, Melvin P, Berry JG, Wolfe J. Trends in Hospital Utilization and Costs among Pediatric Palliative Care Recipients. Journal Of Palliative Medicine 2017, 20: 946-953. PMID: 28453361, DOI: 10.1089/jpm.2016.0496.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildDatabases, FactualEmergency Service, HospitalFemaleHospitalizationHumansMalePalliative CareRetrospective StudiesConceptsPediatric palliative carePPC consultationED visitsHospital admissionHospital costsHospital utilizationAnnual hospital admission rateIntensive care unit usePalliative care recipientsPercent of patientsRetrospective cohort studyAnnual ED visitsEmergency department visitsHospital admission ratesQuaternary children's hospitalYears of agePPC involvementCohort studyDepartment visitsMedian ageED useSingle centerChildren's HospitalPalliative careIll children