Sex-Differential Gene Expression in Developing Human Cortex and Its Intersection With Autism Risk Pathways
Kissel L, Pochareddy S, An J, Sestan N, Sanders S, Wang X, Werling D. Sex-Differential Gene Expression in Developing Human Cortex and Its Intersection With Autism Risk Pathways. Biological Psychiatry Global Open Science 2024, 4: 100321. PMID: 38957312, PMCID: PMC11217612, DOI: 10.1016/j.bpsgos.2024.100321.Peer-Reviewed Original ResearchCo-expression modulesSex-differential gene expressionRisk genesAutosomal genesAutism spectrum disorderAutism spectrum disorder risk genesRNA-seq data setsGene expressionHuman cortex tissueY chromosome genesCo-expression network analysisASD risk genesX-chromosome inactivationPrenatal cortical developmentGene expression differencesSex-differential expressionMale-biased prevalenceTranscriptomic sex differencesEncode proteinsCell type markersSex differencesImmune signalingSex differentiationType markersExpression differences