2017
Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila
Chen D, Sitaraman D, Chen N, Jin X, Han C, Chen J, Sun M, Baker BS, Nitabach MN, Pan Y. Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila. Nature Communications 2017, 8: 154. PMID: 28754889, PMCID: PMC5533705, DOI: 10.1038/s41467-017-00087-5.Peer-Reviewed Original ResearchA Peptidergic Circuit Links the Circadian Clock to Locomotor Activity
King AN, Barber AF, Smith AE, Dreyer AP, Sitaraman D, Nitabach MN, Cavanaugh DJ, Sehgal A. A Peptidergic Circuit Links the Circadian Clock to Locomotor Activity. Current Biology 2017, 27: 1915-1927.e5. PMID: 28669757, PMCID: PMC5698909, DOI: 10.1016/j.cub.2017.05.089.Peer-Reviewed Original ResearchConceptsLocomotor activitySubesophageal zonePeptidergic circuitsPars intercerebralisCorticotropin-releasing factorVentral nerve cordSite of actionReceptor 1Motor outputCircadian locomotor activityNerve cordNeuronsRelevant receptorsDrosophila brainHr rhythmsCircadian driveRhythmFeeding rhythmDiuretic hormone 44Minimal effectActivity rhythmsBehavioral rhythmsCircadian locomotionCircadian controlCord
2015
Propagation of Homeostatic Sleep Signals by Segregated Synaptic Microcircuits of the Drosophila Mushroom Body
Sitaraman D, Aso Y, Jin X, Chen N, Felix M, Rubin GM, Nitabach MN. Propagation of Homeostatic Sleep Signals by Segregated Synaptic Microcircuits of the Drosophila Mushroom Body. Current Biology 2015, 25: 2915-2927. PMID: 26455303, PMCID: PMC4654684, DOI: 10.1016/j.cub.2015.09.017.Peer-Reviewed Original ResearchConceptsSynaptic microcircuitsDrosophila mushroom bodyKenyon cellsMushroom bodiesMB neuronsControl of sleepHomeostatic rebound sleepHomeostatic sleep regulationIncreases sleepRebound sleepSleep regulationMBONsSleep deprivationNeuron classesSleepSleep informationMemory centerSpecific functional connectionsFunctional connectionsNeuronsPhysiological approachDifferent populationsMicrocircuits