2024
Assessing the Efficacy of Large Language Models in Health Literacy: A Comprehensive Cross-Sectional Study
Amin K, Mayes L, Khosla P, Doshi R. Assessing the Efficacy of Large Language Models in Health Literacy: A Comprehensive Cross-Sectional Study. The Yale Journal Of Biology And Medicine 2024, 97: 17-27. PMID: 38559461, PMCID: PMC10964816, DOI: 10.59249/ztoz1966.Peer-Reviewed Original ResearchConceptsImprove health literacyReading grade levelHealth literacyEnhance health literacyCross-sectional studyComprehensive cross-sectional studyPrimary outcome measureGrade levelFlesch-Kincaid Grade LevelHealth outcomesHealth conditionsOutcome measuresPediatric conditionsHealthFlesch-KincaidGunning FogColeman-Liau IndexLanguage modelSeventh-gradersAutomated Readability IndexWord countLiteracyNeural correlates of altered emotional responsivity to infant stimuli in mothers who use substances
McCurdy L, Yip S, Worhunsky P, Zhai Z, Kim S, Strathearn L, Potenza M, Mayes L, Rutherford H. Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances. Journal Of Psychiatric Research 2024, 171: 126-133. PMID: 38277872, PMCID: PMC10922955, DOI: 10.1016/j.jpsychires.2024.01.024.Peer-Reviewed Original ResearchConceptsResponses to infant stimuliInfant stimuliMaternal behaviorAffective processesBrain regionsPsychological processesEmotional responsesFunctional magnetic resonance imagingPotential neural targetsInfant emotional expressionsMaternal emotional responsivenessSubstance-use statusAssociated with difficultiesSocial-emotional developmentInfant social-emotional developmentMaternal substance useInfant facesCognitive processesImprove child outcomesEmotional expressionEmotional intensityNeural targetsSubstance useGroups of mothersChild outcomes
2023
Participation in an Attachment-Based Home Visiting Program Is Associated with Lower Child Salivary C-Reactive Protein Levels at Follow-Up
Tobón A, Condon E, Slade A, Holland M, Mayes L, Sadler L. Participation in an Attachment-Based Home Visiting Program Is Associated with Lower Child Salivary C-Reactive Protein Levels at Follow-Up. Journal Of Developmental And Behavioral Pediatrics 2023, 44: e292-e299. PMID: 37126599, PMCID: PMC10353420, DOI: 10.1097/dbp.0000000000001180.Peer-Reviewed Original ResearchConceptsSalivary inflammatory biomarkersInflammatory biomarkersEarly childhood adversityC-reactive protein levelsChildhood adversitySalivary cytokine levelsEarly adversityMaternal-child dyadsHome Visiting ProgramSalivary CRP levelsMother-infant dyadsBlack/African AmericanHispanics/LatinosRCT completionCRP levelsCytokine levelsFollow-upSalivary specimensVisiting ProgramEarly interventionNegative psychosocial outcomesPsychosocial outcomesLong-term biological effectsProtein levelsMtbLong-term neurocognitive outcomes in 204 single-suture craniosynostosis patients
Junn A, Long A, Hauc S, Almeida M, Alper D, Rivera J, Mayes L, Persing J, Alperovich M. Long-term neurocognitive outcomes in 204 single-suture craniosynostosis patients. Child's Nervous System 2023, 39: 1921-1928. PMID: 36877207, DOI: 10.1007/s00381-023-05908-1.Peer-Reviewed Original ResearchConceptsFull Scale IQVisuomotor integrationVisual perceptionVerbal IQNeurocognitive testingVisual perception scoresHigher scoresLong-term neurocognitive outcomesCognitive profileWhite matter connectionsNeurocognitive deficitsIQPerception scoresMean IQNeurocognitive outcomesFrontal lobeLower scoresMotor controlMotor coordinationPerceptionNon-syndromic craniosynostosisUnicoronal synostosisScoresChildren 6
2022
Quantitative MRI Characterization of the Extremely Preterm Brain at Adolescence: Atypical versus Neurotypical Developmental Pathways
McNaughton R, Pieper C, Sakai O, Rollins J, Zhang X, Kennedy D, Frazier J, Douglass L, Heeren T, Fry R, O'Shea T, Kuban K, Jara H, Rollins J, Shah B, Singh R, Vaidya R, Van Marter L, Martin C, Ware J, Rollins C, Cole C, Perrin E, Sakai C, Bednarek F, Frazier J, Ehrenkranz R, Benjamin J, Montgomery A, O'Shea T, Washburn L, Gogcu S, Bose C, Warner D, O'Shea T, Engelke S, Higginson A, Higginson J, Bear K, Poortenga M, Pastyrnak S, Karna P, Paneth N, Lenski M, Schreiber M, Hunter S, Msall M, Batton D, Klarr J, Lee Y, Obeid R, Christianson K, Klein D, Wagner K, Pimental M, Hallisey C, Coster T, Dolins M, Mittleman M, Haile H, Rohde J, Nylen E, Neger E, Mattern K, Ma C, Toner D, Vitaro E, Venuti L, Powers B, Foley A, Sacco T, Williams J, Romano E, Henry C, Hiatt D, Peters N, Brown P, Ansusinha E, Smith J, Yang N, Bose G, Wereszczak J, Bernhardt J, Adams J, Wilson D, Darden-Saad N, Williams B, Jones E, Sutton D, Rathbun J, Fagerman S, Boshoven W, Johnson J, James B, Miras K, Solomon C, Weiland D, Yoon G, Ramoskaite R, Wiggins S, Washington K, Martin R, Prendergast B, Lynch E, Kring B, Smith A, McQuiston S, Butler S, Wilson R, McGhee K, Lee P, Asgarian A, Sadhwani A, Henson B, Keller C, Walkowiak J, Barron S, Miller A, Dessureau B, Wood M, Damon-Minow J, Romano E, Mayes L, Tsatsanis K, Chawarska K, Kim S, Dieterich S, Bearrs K, Waldrep E, Friedman J, Hounshell G, Allred D, Helms R, Whitley L, Stainback G, Bostic L, Jacobson A, McKeeman J, Meyer E, Price J, Lloyd M, Plesha-Troyke S, Scott M, Solomon K, Brooklier K, Vogt K. Quantitative MRI Characterization of the Extremely Preterm Brain at Adolescence: Atypical versus Neurotypical Developmental Pathways. Radiology 2022, 304: 419-428. PMID: 35471112, PMCID: PMC9340244, DOI: 10.1148/radiol.210385.Peer-Reviewed Original ResearchConceptsWhite matterPerinatal white matter injuryExtremely preterm birthsProspective multicenter studyWhite matter injuryPreterm birthCerebral palsyMRI evaluationMulticenter studyClinical correlatesNeurocognitive outcomesHigh riskCerebrospinal fluidQuantitative MRI parametersCognitive impairmentMRI biomarkersGray matterMRI parametersCSF volumeBrain developmentModerate negative associationAdolescentsBoysGirlsAutism spectrum disorder
2005
Event-related potentials in cocaine-exposed children during a Stroop task
Mayes LC, Molfese DL, Key AP, Hunter NC. Event-related potentials in cocaine-exposed children during a Stroop task. Neurotoxicology And Teratology 2005, 27: 797-813. PMID: 16111858, DOI: 10.1016/j.ntt.2005.05.011.Peer-Reviewed Original ResearchConceptsStroop paradigmCortical functioningEvent-related potentialsCocaine-exposed childrenEarly cocaine exposureCognitive processingStroop taskCE childrenExecutive functionERP methodologyDevelopmental courseCognitive functionTask processingFrontal maturationPotential studiesCocaine exposureInitial positive peakRegion involvementPositive peakChildrenFunctioningCocaine effectsCortical involvementParadigmMore time
2004
Impaired performance of children exposed in utero to cocaine on a novel test of visuospatial working memory
Schroder MD, Snyder PJ, Sielski I, Mayes L. Impaired performance of children exposed in utero to cocaine on a novel test of visuospatial working memory. Brain And Cognition 2004, 55: 409-412. PMID: 15177825, DOI: 10.1016/j.bandc.2004.02.062.Peer-Reviewed Original ResearchConceptsMaze Learning TestCocaine-exposed groupLearning TestRecall trialsGroton Maze Learning TestVisuospatial working memoryVisuospatial memory functionShort-term memoryInternal spatial mapPrenatal cocaine exposureChase testSignificant group differencesWorking memoryNeuropsychological measuresVisuospatial informationProcedural learningVisuomotor speedLearning trialsImpaired performanceMore errorsMemory functionGroup differencesCocaine exposureMin delayPossible impairment
2001
Sensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial
Kain Z, Wang S, Mayes L, Krivutza D, Teague B. Sensory Stimuli and Anxiety in Children Undergoing Surgery: A Randomized, Controlled Trial. Anesthesia & Analgesia 2001, 92: 897-903. PMID: 11273921, DOI: 10.1097/00000539-200104000-00018.Peer-Reviewed Original ResearchConceptsInduction of anesthesiaChildren Undergoing SurgeryPostoperative day 1Postoperative behavioral changesSensory stimuliPost Hospitalization Behavior QuestionnaireUndergoing surgeryBehavioral recoveryIncreased complianceStimulation groupDay 1AnesthesiaControl groupAnesthesia maskOperating room lightsSurgeryAnxiety of childrenBehavioral interventionsOperating roomChildrenBehavioral changesExhibit low levelsBehavior QuestionnaireInductionAnxietyDevelopmental themes in women's emotional experiences of motherhood
LUTHAR S, DOYLE K, SUCHMAN N, MAYES L. Developmental themes in women's emotional experiences of motherhood. Development And Psychopathology 2001, 13: 165-182. PMID: 11346050, PMCID: PMC3314384, DOI: 10.1017/s0954579401001110.Peer-Reviewed Original ResearchConceptsEgo developmentEmotional experiencePsychological difficultiesWashington University Sentence Completion TestSentence Completion TestHigher developmental levelDiverse socioeconomic backgroundsMaternal roleFeeling of satisfactionPositive emotionsIntrapsychic forcesWomen's emotional experiencesChild-rearing experiencesAdjustment problemsCompletion TestDevelopmental levelHypothetical vignettesMaternal substance abuseDevelopmental themesSubstance abuseGlobal symptomatologyInteraction effectsSocioeconomic backgroundFeelingsOutcome variablesThe Twin Poles of Order and Chaos
Mayes L. The Twin Poles of Order and Chaos. The Psychoanalytic Study Of The Child 2001, 56: 137-170. PMID: 12102010, DOI: 10.1080/00797308.2001.11800671.Peer-Reviewed Original ResearchConceptsDevelopmental perspectiveTheories of developmentPsychoanalytic developmental perspectiveLevel of fantasyPsychological developmentDevelopmental theoryChild developmentPsychoanalytic perspectiveConstant dialecticSystems theoryThird questionDiversity of theoriesGeneral systems theoryDifferent perspectivesPerspectiveTheoryTaskQuestionsAttitudesChildrenEpigenesisAdultsFantasyDisordersTwin poles
2000
Social adaptability, cognitive abilities, and other predictors for children’s reactions to surgery
Kain Z, Mayes L, Weisman S, Hofstadter M. Social adaptability, cognitive abilities, and other predictors for children’s reactions to surgery. Journal Of Clinical Anesthesia 2000, 12: 549-554. PMID: 11137417, DOI: 10.1016/s0952-8180(00)00214-2.Peer-Reviewed Original ResearchConceptsCognitive abilitiesSocial adaptabilityParental anxietyPerioperative anxietyGroup of childrenChild temperamentChildren's reactionsAnxious parentsCorrelational analysisParental stateAdaptive behaviorPersonality characteristicsHigh intelligenceAnxietyAge 3TemperamentChildrenStylePredictorsSurgical childrenPersonalityAbilityRegression analysisHigh levelsIntelligenceMidazolam: Effects on Amnesia and Anxiety in Children
Kain Z, Hofstadter M, Mayes L, Krivutza D, Alexander G, Wang S, Reznick J. Midazolam: Effects on Amnesia and Anxiety in Children. Anesthesiology 2000, 93: 676. PMID: 10969300, DOI: 10.1097/00000542-200009000-00016.Peer-Reviewed Original ResearchConceptsOral midazolamMidazolam administrationAnterograde amnesiaGood anterograde amnesiaSignificant anterograde amnesiaInduction of anesthesiaSignificant anxiolytic effectMidazolam groupGeneral anesthesiaSignificant group differencesAnxiolytic effectsBusy operating roomSurgical proceduresPostintervention testingDrug AdministrationControl groupMidazolamBaseline testingAnxiety measurement toolAnxiety of childrenOperating roomAdministrationGroup differencesPicture cardsAnesthesiaThe Mother-Child Dyad Facing Trauma
WOLMER L, LAOR N, GERSHON A, MAYES L, COHEN D. The Mother-Child Dyad Facing Trauma. The Journal Of Nervous And Mental Disease 2000, 188: 409-415. PMID: 10919698, DOI: 10.1097/00005053-200007000-00003.Peer-Reviewed Original ResearchParental Presence and a Sedative Premedicant for Children Undergoing Surgery
Kain Z, Mayes L, Wang S, Caramico L, Krivutza D, Hofstadter M. Parental Presence and a Sedative Premedicant for Children Undergoing Surgery. Anesthesiology 2000, 92: 939-946. PMID: 10754612, DOI: 10.1097/00000542-200004000-00010.Peer-Reviewed Original ResearchConceptsPPIA groupSedative groupOverall careParental presenceParental satisfactionOperating roomParental anxietyInduction of anesthesiaPrimary endpointSecondary endpointsPerioperative periodOral midazolamOral sedativesPreoperative anxietySedative premedicantsAnesthesia maskChildrenSedativesAnxietyAdditive effectChild anxietyEndpointCareStandardized measuresIntervention
1999
Preoccupations and Behaviors Associated with Romantic and Parental Love: Perspectives on the Origin of Obsessive-Compulsive Disorder
Leckman J, Mayes L. Preoccupations and Behaviors Associated with Romantic and Parental Love: Perspectives on the Origin of Obsessive-Compulsive Disorder. Child And Adolescent Psychiatric Clinics Of North America 1999, 8: 635-665. PMID: 10442234, DOI: 10.1016/s1056-4993(18)30172-x.Peer-Reviewed Original ResearchDistress during the induction of anesthesia and postoperative behavioral outcomes.
Kain Z, Wang S, Mayes L, Caramico L, Hofstadter M. Distress during the induction of anesthesia and postoperative behavioral outcomes. Anesthesia & Analgesia 1999, 88: 1042-7. PMID: 10320165, DOI: 10.1097/00000539-199905000-00013.Peer-Reviewed Original ResearchDistress During the Induction of Anesthesia and Postoperative Behavioral Outcomes
Kain Z, Wang S, Mayes L, Caramico L, Hofstadter M. Distress During the Induction of Anesthesia and Postoperative Behavioral Outcomes. Anesthesia & Analgesia 1999, 88: 1042-1047.. DOI: 10.1213/00000539-199905000-00013.Peer-Reviewed Original ResearchPostoperative Behavioral Outcomes in Children
Kain Z, Mayes L, Wang S, Hofstadter M. Postoperative Behavioral Outcomes in Children. Anesthesiology 1999, 90: 758-765. PMID: 10078677, DOI: 10.1097/00000542-199903000-00018.Peer-Reviewed Original ResearchConceptsPostoperative behavioral outcomesPostoperative day 1Induction of anesthesiaNegative behavioral changesPlacebo groupDay 1Multivariate logistic regression modelRecent stressful life eventsBehavioral changesFirst postoperative weekPostoperative behavioral changesPaucity of dataLogistic regression modelsPost Hospitalization Behavior QuestionnaireBehavioral outcomesMidazolam groupStressful life eventsPostoperative weekBehavioral recoveryIntervention groupPreoperative anxietyWeek 2Lower anxiety levelsSedative premedicationMeasures of anxiety
1998
Preoperative preparation programs in children: a comparative examination.
Kain Z, Caramico L, Mayes L, Genevro J, Bornstein M, Hofstadter M. Preoperative preparation programs in children: a comparative examination. Anesthesia & Analgesia 1998, 87: 1249-55. PMID: 9842807, DOI: 10.1097/00000539-199812000-00007.Peer-Reviewed Original ResearchPreoperative Preparation Programs in Children
Kain Z, Caramico L, Mayes L, Genevro J, Bornstein M, Hofstadter M. Preoperative Preparation Programs in Children. Anesthesia & Analgesia 1998, 87: 1249-1255.. DOI: 10.1213/00000539-199812000-00007.Peer-Reviewed Original Research