2024
Chemical entity normalization for successful translational development of Alzheimer’s disease and dementia therapeutics
Mullin S, McDougal R, Cheung K, Kilicoglu H, Beck A, Zeiss C. Chemical entity normalization for successful translational development of Alzheimer’s disease and dementia therapeutics. Journal Of Biomedical Semantics 2024, 15: 13. PMID: 39080729, PMCID: PMC11290083, DOI: 10.1186/s13326-024-00314-1.Peer-Reviewed Original ResearchMeSH KeywordsAlzheimer DiseaseBiological OntologiesDementiaHumansNatural Language ProcessingTranslational Research, BiomedicalConceptsEntity normalizationChemical mentionsNatural language modelDictionary-based methodsDictionary-based approachCRAFT corpusDownstream tasksLanguage modelChemical Entities of Biological InterestPubMedBERT modelDisambiguationChEBIDownstream applicationsArticle abstractsRelationship typesMentionsPubMedBERTOntologyDementia literatureTaskDementia CohortMethodEntitiesAccuracyDementia
2007
AlzPharm: integration of neurodegeneration data using RDF
Lam H, Marenco L, Clark T, Gao Y, Kinoshita J, Shepherd G, Miller P, Wu E, Wong GT, Liu N, Crasto C, Morse T, Stephens S, Cheung KH. AlzPharm: integration of neurodegeneration data using RDF. BMC Bioinformatics 2007, 8: s4. PMID: 17493287, PMCID: PMC1892101, DOI: 10.1186/1471-2105-8-s3-s4.Peer-Reviewed Original ResearchMeSH KeywordsBrainDatabase Management SystemsDatabases, FactualDocumentationHumansInformation DisseminationInformation Storage and RetrievalInternationalityInternetNatural Language ProcessingNerve Tissue ProteinsNeurodegenerative DiseasesNeurosciencesPilot ProjectsResearchResearch DesignSemanticsSystems IntegrationConceptsResource Description FrameworkSemantic Web approachWeb approachData modelData setsRDF data modelStandard data modelHeterogeneous data setsData integration approachData of interestMultiple research domainsRDF SchemaDescription FrameworkDomain ontologyAdvanced queriesOracle databaseDescription languageWeb interfaceBiomedical dataData integrationSeamless integrationNeuroscience dataOntological structureResearch domainNeuroscience researchers