2020
Combined (endo-)vascular intervention and microsurgical lower extremity free flap reconstruction—A propensity score matching analysis in 5386 ACS-NSQIP patients
Haug V, Kadakia N, Panayi AC, Kauke M, Hundeshagen G, Diehm Y, Fischer S, Hirche C, Kneser U, Pomahac B. Combined (endo-)vascular intervention and microsurgical lower extremity free flap reconstruction—A propensity score matching analysis in 5386 ACS-NSQIP patients. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 74: 1031-1040. PMID: 33436337, DOI: 10.1016/j.bjps.2020.10.045.Peer-Reviewed Original ResearchConceptsFree flap reconstructionLower extremity free flap reconstructionFlap reconstructionLimb amputationNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseAnesthesiology physical status classificationQuality Improvement Program databaseMicrosurgical free flap reconstructionPropensity scoreACS-NSQIP patientsLower limb perfusionPreoperative steroid usePropensity-matched cohortImprovement Program databaseModifiable risk factorsPeripheral artery diseasePhysical status classificationCareful preoperative assessmentSick patient populationLower limb amputationLower extremity salvageLower limb reconstructionFree flap transferFree tissue transfer
2019
The Importance of Serological Procalcitonin Levels After Autologous Microsurgical Transplantation
Safi AF, Schröder K, Kauke M, Safi S, Zöller JE, Zinser M. The Importance of Serological Procalcitonin Levels After Autologous Microsurgical Transplantation. Journal Of Craniofacial Surgery 2019, Publish Ahead of Print: &na;. PMID: 30817542, DOI: 10.1097/scs.0000000000005431.Peer-Reviewed Original ResearchConceptsSoft tissue defectsPCT levelsProcalcitonin levelsSystemic inflammationMicrosurgical interventionTissue defectsPCT cutoff levelPerioperative systemic inflammationHigh mortality rateMicrovascular transplantsMicrovascular transplantationSevere complicationsSevere morbidityRetrospective studySurgical interventionTransplant lossMicrosurgical transplantationTreatment strategiesInclusion criteriaCutoff levelMortality ratePatientsReconstructive surgeonPathological levelsDetectable increaseVein Graft Interposition: A Training Model Using Gradually Thawed Cryopreserved Vessels.
Safi AF, Safi S, Tayeh M, Gojowy D, Timmer M, Goldbrunner R, Kauke M. Vein Graft Interposition: A Training Model Using Gradually Thawed Cryopreserved Vessels. Journal Of Craniofacial Surgery 2019, 30: e213-e216. PMID: 30845093, DOI: 10.1097/scs.0000000000005197.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCryopreservationFemoral ArteryFemoral VeinHumansMicrosurgeryModels, EducationalRatsVascular Grafting
2018
A novel microsurgical anastomosis training model using gradually thawed cryopreserved microvessels of rat cadavers
Safi AF, Safi S, Tayeh M, Timmer M, Goldbrunner R, Kauke M. A novel microsurgical anastomosis training model using gradually thawed cryopreserved microvessels of rat cadavers. Journal Of Cranio-Maxillofacial Surgery 2018, 46: 1126-1131. PMID: 29802058, DOI: 10.1016/j.jcms.2018.05.018.Peer-Reviewed Original ResearchConceptsCommon carotid arteryExternal jugular veinFemoral vesselsVenous anastomosisLocal ethics committeePatency failurePatency ratesFemoral arteryVein anastomosisCarotid arteryJugular veinMicrovessel anastomosesNeck anatomyCadaveric studyAnastomosisPrior microsurgical experienceSurgical anatomyMicrosurgical experienceAnatomical dissectionEthics CommitteeOperation timeNovel training modelAverage timeArteryCadaveric vesselsDoes volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma?
Safi AF, Kauke M, Jung H, Timmer M, Borggrefe J, Persigehl T, Nickenig HJ, Zinser M, Maintz D, Kreppel M, Zöller J. Does volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma? Journal Of Cranio-Maxillofacial Surgery 2018, 46: 1013-1018. PMID: 29709330, DOI: 10.1016/j.jcms.2018.04.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkersCarcinoma, Squamous CellChemoradiotherapyFemaleHumansLymph NodesLymphatic MetastasisMaleMicrosurgeryMiddle AgedMouth NeoplasmsMultivariate AnalysisNeckNeck DissectionNeoadjuvant TherapyNeoplasm Recurrence, LocalPrognosisRetrospective StudiesRisk FactorsTomography, X-Ray ComputedConceptsOral squamous cell carcinomaLymph node volumeSquamous cell carcinomaLocoregional recurrenceN classificationCell carcinomaNode volumeInclusion criteriaComputed tomographyTreatment-naive oral squamous cell carcinomaIpsilateral lymph node metastasisBetter risk stratification toolsComprehensive neck dissectionPathological N classificationCervical lymph nodesNegative resection marginsRetrospective chart reviewRisk stratification toolLymph node metastasisPreoperative computed tomographyVolumetric measurementsT4b classificationUnresectable diseaseLocoregional failureNeoadjuvant chemoradiotherapy