Featured Publications
Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments
Coronas-Samano G, Baker KL, Tan WJ, Ivanova AV, Verhagen JV. Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments. Frontiers In Aging Neuroscience 2016, 8: 268. PMID: 27895577, PMCID: PMC5108791, DOI: 10.3389/fnagi.2016.00268.Peer-Reviewed Original ResearchSporadic Alzheimer's diseaseKO miceOxidative stressAlzheimer's diseaseYounger ageWT adult miceOlfactory memory impairmentsEffective therapeutic treatmentMore sleep timeClear deficitNeurobehavioral deficitsRisk factorsAD hallmarksMetabolic dysregulationOlfactory bulbAdult miceAnimal modelsSleep timeEarly interventionMemory impairmentAD etiologyPharmacological targetsTherapeutic treatmentCircadian disruptionMice
2015
Direct Behavioral and Neurophysiological Evidence for Retronasal Olfaction in Mice
Rebello MR, Kandukuru P, Verhagen JV. Direct Behavioral and Neurophysiological Evidence for Retronasal Olfaction in Mice. PLOS ONE 2015, 10: e0117218. PMID: 25675095, PMCID: PMC4326425, DOI: 10.1371/journal.pone.0117218.Peer-Reviewed Original ResearchConceptsOlfactory bulbMouse's abilityAdditional animal modelsHead-fixed miceConcentration-dependent mannerAnesthetized ratsAwake miceRetronasal odorantsRetronasal odorCalcium responseAnimal modelsTransgenic miceMiceRatsRetronasal olfactionGo behavioral taskRetronasal smellLick spoutFood flavor perceptionNeurophysiological evidenceBehavioral tasksHuman flavor perceptionFood selectionOlfactionBulbectomy