Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's Disease
Weiss LM, Movahed LA, Warnke RA, Sklar J. Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's Disease. New England Journal Of Medicine 1989, 320: 502-506. PMID: 2536894, DOI: 10.1056/nejm198902233200806.Peer-Reviewed Original ResearchConceptsReed-Sternberg cellsEpstein-Barr virusHodgkin's diseaseSlot blot hybridizationEBV genomeBiopsy tissueTissue specimensEpstein-Barr viral genomeEBV nucleic acidsBlot hybridizationEBV DNASitu hybridizationSouthern blot hybridizationPositive specimensDiseasePatientsInfected cellsTissueIntense hybridizationSuch tissuesCellsViral genomePrevious studiesMonoclonality