2024
Olfactory sensory neuron population expansions influence projection neuron adaptation and enhance odour tracking
Takagi S, Sancer G, Abuin L, Stupski S, Roman Arguello J, Prieto-Godino L, Stern D, Cruchet S, Álvarez-Ocaña R, Wienecke C, van Breugel F, Jeanne J, Auer T, Benton R. Olfactory sensory neuron population expansions influence projection neuron adaptation and enhance odour tracking. Nature Communications 2024, 15: 7041. PMID: 39147786, PMCID: PMC11327376, DOI: 10.1038/s41467-024-50808-w.Peer-Reviewed Original ResearchConceptsOlfactory sensory neuronsPopulation expansionSpecies-specific expansionSensory neuronsProjection neuronsConnections of sensory neuronsOlfactory sensory neuron numbersSpecies-specific behaviorsD. sechelliaDrosophila sechelliaEcologically-relevantProportion of neuronsEnvironmental cuesMultigenic changesEvolutionary expansionIncreased synaptic connectivityFunctional impactPN sensitivityNeuronal adaptationOdor trackingNeuronsSechelliaLateral inhibitionInhibitionSpecies
2021
An ammonium transporter is a non-canonical olfactory receptor for ammonia
Vulpe A, Kim HS, Ballou S, Wu ST, Grabe V, Nava Gonzales C, Liang T, Sachse S, Jeanne JM, Su CY, Menuz K. An ammonium transporter is a non-canonical olfactory receptor for ammonia. Current Biology 2021, 31: 3382-3390.e7. PMID: 34111404, PMCID: PMC8355169, DOI: 10.1016/j.cub.2021.05.025.Peer-Reviewed Original ResearchMeSH KeywordsAmmoniaAmmonium CompoundsAnimalsDrosophila melanogasterDrosophila ProteinsOlfactory Receptor NeuronsReceptors, OdorantConceptsOlfactory receptorsGenetic model organism Drosophila melanogasterModel organism Drosophila melanogasterAmmonium transporter familyCanonical olfactory receptorsIon channel functionAmmonium transportersInsect speciesDrosophila melanogasterMost insectsMutant fliesFirst transporterParticular olfactory receptorTransporter familyAgricultural pestsHematophagous insectsEctopic expressionDrosophilaInsectsChannel functionWidespread importanceAmmonia sensitivitySpeciesTransportersReceptors
2018
The Organization of Projections from Olfactory Glomeruli onto Higher-Order Neurons
Jeanne JM, Fişek M, Wilson RI. The Organization of Projections from Olfactory Glomeruli onto Higher-Order Neurons. Neuron 2018, 98: 1198-1213.e6. PMID: 29909998, PMCID: PMC6051339, DOI: 10.1016/j.neuron.2018.05.011.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainConnectomeDrosophilaMushroom BodiesNeuronsOlfactory BulbOlfactory PathwaysOlfactory Receptor NeuronsOptogeneticsReceptors, Odorant