Featured Publications
Early detection rate changes from a brain‐responsive neurostimulation system predict efficacy of newly added antiseizure drugs
Quraishi IH, Mercier MR, Skarpaas TL, Hirsch LJ. Early detection rate changes from a brain‐responsive neurostimulation system predict efficacy of newly added antiseizure drugs. Epilepsia 2019, 61: 138-148. PMID: 31849045, PMCID: PMC7003822, DOI: 10.1111/epi.16412.Peer-Reviewed Original ResearchConceptsPositive predictive valueEpisode startsLonger episodesSystem patientsPredictive valueFirst weekLong-term treatment trialsBrain-responsive neurostimulationSingle epilepsy centerSingle-center cohortRefractory focal epilepsyGreater reductionMedication adjustmentsClinical improvementClinical responseSeizure frequencyAntiseizure drugsCenter cohortMulticenter cohortEpilepsy centersMedication trialsEffective medicationsEfficacy measuresTreatment trialsFocal epilepsy
2022
Evaluating consciousness and awareness during focal seizures: responsiveness testing versus recall testing
Ramirez V, Litvinov B, Gunawardane NA, Zhao CW, Yotter C, Quraishi IH, Blumenfeld H. Evaluating consciousness and awareness during focal seizures: responsiveness testing versus recall testing. Epileptic Disorders 2022, 24: 899-905. PMID: 35904040, PMCID: PMC10042123, DOI: 10.1684/epd.2022.1472.Peer-Reviewed Original ResearchConceptsFocal seizuresResponsiveness testingCurrent International LeagueClinical practice settingEEG-video monitoringEpilepsy monitoring unitImportant clinical settingsEpilepsy guidelinesPatient groupFocal epilepsyIctal eventsClinical careInternational LeagueSeizuresPatientsClinical settingPractice settingsClassification guidelinesFurther studiesEpilepsyResponsivenessRecall of experiencesPreliminary findingsRecall testingSetting
2021
Electrical cortical stimulation can impair production of the alphabet without impairing counting
Rojas PH, Sivaraju A, Quraishi IH, Vanderlind M, Rofes A, Połczynska-Bletsos MM, Spencer DD, Hirsch LJ, Benjamin CFA. Electrical cortical stimulation can impair production of the alphabet without impairing counting. Epilepsy & Behavior Reports 2021, 15: 100433. PMID: 33778464, PMCID: PMC7985277, DOI: 10.1016/j.ebr.2021.100433.Peer-Reviewed Case Reports and Technical NotesElectrical stimulation mappingCortical electrical stimulation mappingDrug-resistant focal epilepsyPatient experienced lossDrug-resistant epilepsyElectrical cortical stimulationLanguage-dominant hemisphereSuperior temporal gyrusPosterior superior temporal gyrusCortical stimulationFocal epilepsyStimulation mappingDominant hemispherePatientsTemporal gyrusSelective impairmentLanguage functionEpilepsyExperienced lossImpairmentBrainRiskLanguage impairmentSurgerySole means
2017
Impairment of consciousness induced by bilateral electrical stimulation of the frontal convexity
Quraishi IH, Benjamin CF, Spencer DD, Blumenfeld H, Alkawadri R. Impairment of consciousness induced by bilateral electrical stimulation of the frontal convexity. Epilepsy & Behavior Reports 2017, 8: 117-122. PMID: 29204347, PMCID: PMC5707211, DOI: 10.1016/j.ebcr.2017.09.006.Peer-Reviewed Case Reports and Technical NotesElectrical cortical stimulationLoss of consciousnessCortical stimulationFrontal convexityFocal cortical stimulationIntracranial EEG evaluationBilateral electrical stimulationImpairment of consciousnessCessation of stimulationLateral frontal lobeFronto-parietal areasIntractable epilepsyIctal dischargesRarity of reportsElectrophysiological findingsFocal epilepsyEpileptic focusEEG evaluationIntracranial EEG recordingsCase of impairmentCortical connectivityElectrical stimulationEpileptic seizuresFrontal lobeSubcortical structures