2024
Single-cell analysis reveals transcriptional dynamics in healthy primary parathyroid tissue.
Venkat A, Carlino M, Lawton B, Prasad M, Amodio M, Gibson C, Zeiss C, Youlten S, Krishnaswamy S, Krause D. Single-cell analysis reveals transcriptional dynamics in healthy primary parathyroid tissue. Genome Research 2024, 34: 837-850. PMID: 38977309, PMCID: PMC11293540, DOI: 10.1101/gr.278215.123.Peer-Reviewed Original ResearchCell statesMitochondrial transcript abundanceParathyroid glandsHuman parathyroidCell-cell communication analysisRNA expression analysisSingle-cell analysisTranscriptional dynamicsTranscript abundanceExpression dynamicsRNA transcriptomeEpithelial cell statesCell abundanceExpression analysisPseudotime analysis
2023
Uncovering Primary Extranodal Diffuse Large B Cell Lymphoma in the Adrenal and Thyroid Glands
Li J, Balbuena-Merle R, Hrones M, Gibson C. Uncovering Primary Extranodal Diffuse Large B Cell Lymphoma in the Adrenal and Thyroid Glands. American Journal Of Case Reports 2023, 25: e942659. PMID: 38287660, PMCID: PMC10838563, DOI: 10.12659/ajcr.942659.Peer-Reviewed Original ResearchCorrection to: Endocrine Organs
Billmann F, Gibson C, Udelsman R. Correction to: Endocrine Organs. 2023, c1-c1. DOI: 10.1007/978-3-662-66735-4_17.Peer-Reviewed Original ResearchEndocrine Organs
Billmann F, Gibson C, Udelsman R. Endocrine Organs. 2023, 113-179. DOI: 10.1007/978-3-662-66735-4_6.Peer-Reviewed Original Research
2022
Retroperitoneoscopic adrenalectomy: indications and technical considerations
McCoy K, Valdez C, Gibson C. Retroperitoneoscopic adrenalectomy: indications and technical considerations. Laparoscopic Surgery 2022, 0: 0-0. DOI: 10.21037/ls-21-24.Peer-Reviewed Original ResearchGiant Parathyroid Adenomas: Differential Aspects Compared to Atypical Parathyroid Adenomas
McCoy K, Bakkila B, Gibson C. Giant Parathyroid Adenomas: Differential Aspects Compared to Atypical Parathyroid Adenomas. Journal Of Endocrine Surgery 2022, 22: 92. DOI: 10.16956/jes.2022.22.3.92.Peer-Reviewed Original ResearchBenign Recurrent Primary Hyperparathyroidism After Parathyroid Carcinoma
Jeoffrey S, McCoy K, Gibson C. Benign Recurrent Primary Hyperparathyroidism After Parathyroid Carcinoma. Journal Of Endocrine Surgery 2022, 22: 123. DOI: 10.16956/jes.2022.22.4.123.Peer-Reviewed Original Research
2021
Contemporary Experience of Posterior Retroperitoneoscopic Adrenalectomy in the US
Chiu A, Vargas-Pinto S, Abou-Azar S, Maduka R, Man J, Peters N, Carling T, Gibson C. Contemporary Experience of Posterior Retroperitoneoscopic Adrenalectomy in the US. Journal Of The American College Of Surgeons 2021, 232: 815-821. PMID: 33766728, DOI: 10.1016/j.jamcollsurg.2021.02.018.Peer-Reviewed Original ResearchConceptsPosterior retroperitoneoscopic adrenalectomyPostoperative complicationsRetroperitoneoscopic adrenalectomyComplication rateSingle tertiary care institutionMajor postoperative complicationsMean tumor sizeMinor postoperative complicationsPostoperative day 1Majority of patientsPatient demographic characteristicsPostoperative day 3Retrospective chart reviewTertiary care institutionOutcomes of interestChart reviewPostoperative courseReadmission ratesCommon diagnosisOperative detailsTumor sizeTransabdominal approachOperative lengthMost lesionsInvasive approach
2020
Differentiation of PTH-Expressing Cells From Human Pluripotent Stem Cells
Lawton BR, Martineau C, Sosa JA, Roman S, Gibson CE, Levine MA, Krause DS. Differentiation of PTH-Expressing Cells From Human Pluripotent Stem Cells. Endocrinology 2020, 161: bqaa141. PMID: 32810225, PMCID: PMC7505176, DOI: 10.1210/endocr/bqaa141.Peer-Reviewed Original ResearchRacial disparities in surgical outcomes for benign thyroid disease
Maduka RC, Gibson CE, Chiu AS, Jean RA, Wills-Johnson N, Azar SA, Oliveira K, Ahuja V. Racial disparities in surgical outcomes for benign thyroid disease. The American Journal Of Surgery 2020, 220: 1219-1224. PMID: 32669203, DOI: 10.1016/j.amjsurg.2020.06.054.Peer-Reviewed Original ResearchConceptsBenign thyroid diseaseThyroid diseaseRLN injuryNeck hematomaPostoperative complicationsWhite patientsSurgical outcomesRacial disparitiesRecurrent laryngeal nerve injuryLaryngeal nerve injurySignificant postoperative complicationsMalignant thyroid diseaseSignificant hypocalcemiaNerve injuryPostoperative outcomesPatient factorsSurgical treatmentBlack patientsAsian patientsBenign diseaseThyroid surgeryHigh incidenceGreater oddsPatientsMultivariate analysisThe Unintended Consequences of Nonoperative Management of Acute Appendicitis
Oliveira K, Jean RA, Gonsai R, Maduka RC, Gibson CE, Chiu AS, Ahuja V. The Unintended Consequences of Nonoperative Management of Acute Appendicitis. Journal Of Surgical Research 2020, 255: 436-441. PMID: 32619858, DOI: 10.1016/j.jss.2020.05.018.Peer-Reviewed Original ResearchConceptsNonoperative managementAcute appendicitisNational Readmission DatabaseOdds of readmissionCause readmission rateRisk of readmissionTraditional operative approachMultivariable linear regressionMore comorbiditiesIndex hospitalizationReadmission ratesSurgical managementAdult admissionsOperative approachPatient burdenAppendicitisPatientsSix monthsAppendectomyReadmissionSignificant increaseMost casesLinear regressionManagementComorbiditiesDiffuse large B-cell and follicular lymphoma presenting as a slowly growing compressive goiter: A case report and literature review
Lin N, Vargas-Pinto S, Gisriel S, Xu M, Gibson CE. Diffuse large B-cell and follicular lymphoma presenting as a slowly growing compressive goiter: A case report and literature review. International Journal Of Surgery Case Reports 2020, 72: 615-619. PMID: 32698301, PMCID: PMC7334388, DOI: 10.1016/j.ijscr.2020.06.029.Peer-Reviewed Original ResearchFine needle aspiration cytologyThyroid lymphomaLymphoproliferative processDiffuse large B-cellStage IIE diseaseInvolved-field radiotherapyChronic lymphocytic thyroiditisCore needle biopsyB cell componentLarge B-cellChest lymph nodesChronic lymphocytic infiltrationIIE diseaseIndolent typeStaging workupCompressive symptomsCombination chemotherapyLymph nodesNeck ultrasonographyThyroid lobectomyLymphocytic infiltrationHistological diagnosisHistological subtypesLymphocytic thyroiditisNeck massAssessing National Utilization Trends and Outcomes of Robotic and Endoscopic Thyroidectomy in the United States
Jacobs D, Torabi SJ, Gibson C, Rahmati R, Mehra S, Judson BL. Assessing National Utilization Trends and Outcomes of Robotic and Endoscopic Thyroidectomy in the United States. Otolaryngology 2020, 163: 947-955. PMID: 32539533, DOI: 10.1177/0194599820927699.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseEndoscopic thyroid surgeryRobotic thyroid surgeryThyroid surgeryOpen surgeryRobotic approachNational utilization trendsUnplanned hospital readmissionMultivariable logistic regressionOutcomes of roboticsPostoperative mortalityWorse morbidityComplication rateHospital readmissionEndoscopic thyroidectomyMortality outcomesPositive marginsSurgical approachNational cohortCancer DatabasePatient outcomesEndoscopic approachRetrospective analysisSurgeryOpen approachRecurrent Amplification of the Osmotic Stress Transcription Factor NFAT5 in Adrenocortical Carcinoma
Brown TC, Nicolson NG, Man J, Gibson CE, Stenman A, Juhlin CC, Korah R, Carling T. Recurrent Amplification of the Osmotic Stress Transcription Factor NFAT5 in Adrenocortical Carcinoma. Journal Of The Endocrine Society 2020, 4: bvaa060. PMID: 32587934, PMCID: PMC7304660, DOI: 10.1210/jendso/bvaa060.Peer-Reviewed Original Research
2019
TERT promoter mutations in thyroid cancer: growing evidence for a predictor of poor outcome
Man J, Nicolson N, Gibson C, Carling T. TERT promoter mutations in thyroid cancer: growing evidence for a predictor of poor outcome. Gland Surgery 2019, 8: 301-303. PMID: 31328111, PMCID: PMC6606470, DOI: 10.21037/gs.2019.04.11.Peer-Reviewed Original ResearchInsulin-Like Growth Factor and SLC12A7 Dysregulation: A Novel Signaling Hallmark of Non-Functional Adrenocortical Carcinoma
Brown TC, Nicolson NG, Stenman A, Juhlin CC, Gibson CE, Callender GG, Korah R, Carling T. Insulin-Like Growth Factor and SLC12A7 Dysregulation: A Novel Signaling Hallmark of Non-Functional Adrenocortical Carcinoma. Journal Of The American College Of Surgeons 2019, 229: 305-315. PMID: 31034883, DOI: 10.1016/j.jamcollsurg.2019.04.018.Peer-Reviewed Original ResearchConceptsAdrenocortical carcinomaACC cell linesIGF1 overexpressionInsulin-like growth factorFunctional adrenocortical carcinomaIGF1 receptor activationRelationship of IGFWhole-exome sequencing analysisCancer Genome Atlas (TCGA) databaseEarly-stage tumorsCell linesGene amplificationCopy number variationsGrowth factor dysregulationAdrenal carcinogenesisCancer Genome AtlasExploratory cohortTumor characteristicsPolymerase chain reaction methodLarge tumorsIGF1R activationNCI-H295R.Chain reaction methodIGF treatmentQuantitative polymerase chain reaction methodOrthopaedic Surgery Resident Financial Literacy: An Assessment of Knowledge in Debt, Investment, and Retirement Savings.
Jennings JD, Quinn C, Ly JA, Rehman S. Orthopaedic Surgery Resident Financial Literacy: An Assessment of Knowledge in Debt, Investment, and Retirement Savings. The American Surgeon 2019, 85: 353-358. PMID: 31043194.Peer-Reviewed Original Research
2018
Management of Pheochromocytoma in The Setting of Acute Stroke
Oak S, Javid M, Callender G, Carling T, Gibson C. Management of Pheochromocytoma in The Setting of Acute Stroke. AACE Clinical Case Reports 2018, 4: 245-248. DOI: 10.4158/accr-2017-0077.Peer-Reviewed Original ResearchPeri-operative strokeNormal blood pressureTiming of surgeryCase of pheochromocytomaRare presenting symptomWeeks of treatmentPre-operative managementComputed tomography scanLaparoscopic transabdominal adrenalectomyWeeks of recoverySimilar casesAntihypertensive medicationsMedical blockadeMetaiodobenzylguanidine scanHemorrhagic transformationOrthostatic hypotensionPresenting symptomSevere hypertensionAcute strokeHemodynamic stabilityIschemic strokeOperative complicationsBlood pressureClinical courseTransabdominal adrenalectomy
2017
Identification of distinct cytomorphologic features in the diagnosis of NIFTP at the time of preoperative FNA: Implications for patient management
Chandler JB, Colunga M, Prasad ML, Callender GG, Quinn C, Chhieng D, Adeniran AJ. Identification of distinct cytomorphologic features in the diagnosis of NIFTP at the time of preoperative FNA: Implications for patient management. Cancer Cytopathology 2017, 125: 865-875. PMID: 28834409, DOI: 10.1002/cncy.21910.Peer-Reviewed Original ResearchConceptsFine-needle aspirationPapillary thyroid carcinomaFollicular variantNIFTP casesFVPTC casesCytomorphologic featuresInvasive counterpartsThyroid carcinomaExact testPapillary thyroid carcinoma (FVPTC) subtypesMicrofollicular patternDistinct cytomorphologic featuresPreoperative cytologic evaluationPreoperative fine-needle aspirationOnly independent predictorPapillary-like nuclear featuresDiagnosis of FVPTCNoninvasive follicular thyroid neoplasmFisher's exact testFollicular thyroid neoplasmCases of NIFTPFVPTC subtypesNIFTP diagnosisIndolent natureIndependent predictors
2016
Central venous parathyroid hormone monitoring using a novel, specific anatomic method accurately predicts cure during minimally invasive parathyroidectomy.
Edwards CM, Folek J, Dayawansa S, Govednik CM, Quinn CE, Sigmond BR, Lee CY, Angel MS, Hendricks JC, Lairmore TC. Central venous parathyroid hormone monitoring using a novel, specific anatomic method accurately predicts cure during minimally invasive parathyroidectomy. American Journal Of Surgery 2016, 212: 1154-1161. PMID: 27793324, DOI: 10.1016/j.amjsurg.2016.09.015.Peer-Reviewed Original Research