2024
N-Methyl-d-Aspartate Receptor Antibody and Sensory Gating Deficits in Non-smoking, Minimal Antipsychotic Medication Exposure, and First-Episode Patients With Schizophrenia
Tong J, Yang K, Li W, Wang L, Yin Y, Zhou Y, Huang J, Zhang P, Zhao Y, Chen S, Fan H, Cui Y, Luo X, Tan S, Wang Z, Feng W, Tian B, Li C, Hong L, Tan Y. N-Methyl-d-Aspartate Receptor Antibody and Sensory Gating Deficits in Non-smoking, Minimal Antipsychotic Medication Exposure, and First-Episode Patients With Schizophrenia. Schizophrenia Bulletin 2024, sbae180. PMID: 39406395, DOI: 10.1093/schbul/sbae180.Peer-Reviewed Original ResearchFirst-episode schizophreniaSensory gating deficitsN-methyl-D-aspartate receptorsFirst-episode schizophrenia groupGating deficitsN-methyl-D-aspartateP50 ratioSensory gatingExposure to antipsychotic medicationAb levelsHealthy controlsAntipsychotic medication exposureFirst-episode patientsDiagnosis of schizophreniaImpaired sensory gatingP50 sensory gating deficitN-methyl-D-aspartate receptor antibodiesAntipsychotic medicationFirst-episodeNon-smoking healthy controlsP50 differenceSchizophreniaPartial correlation analysisEnzyme-linked immunosorbent assayDeficits
2021
N-methyl-D-aspartate receptor antibody and the choroid plexus in schizophrenia patients with tardive dyskinesia
Li N, Huang J, Zhang P, Tong J, Chen S, Cui Y, Tan S, Wang Z, Tian B, Li CR, Hong LE, Tian L, Tan Y. N-methyl-D-aspartate receptor antibody and the choroid plexus in schizophrenia patients with tardive dyskinesia. Journal Of Psychiatric Research 2021, 142: 290-298. PMID: 34411812, DOI: 10.1016/j.jpsychires.2021.08.010.Peer-Reviewed Original ResearchConceptsNMDAR antibody levelsNeuronal N-methyl-D-aspartate receptorAbnormal Involuntary Movement ScaleTardive dyskinesiaAntibody levelsCentral nervous systemChoroid plexusAIMS scoresN-methyl-D-aspartate receptor antibodiesSchizophrenia patientsN-methyl-D-aspartate receptorsOrofacial tardive dyskinesiaCP volumeNegative Syndrome ScaleEnzyme-linked immunosorbentNMDAR antibodiesAutoimmune abnormalitiesImmune disturbancesReceptor antibodiesHealthy controlsImmune barrierMovement ScaleNervous systemNTD groupSyndrome Scale