2024
Neural correlates of proactive avoidance deficits and alcohol use motives in problem drinking
Le T, Oba T, Couch L, McInerney L, Li C. Neural correlates of proactive avoidance deficits and alcohol use motives in problem drinking. Translational Psychiatry 2024, 14: 336. PMID: 39168986, PMCID: PMC11339324, DOI: 10.1038/s41398-024-03039-y.Peer-Reviewed Original ResearchConceptsAvoidance deficitNegative emotionsDrinking motivesAlcohol useNeural correlatesProblem drinkingRight anterior insula activityAssociated with greater alcohol useAnterior insula activityAlcohol use motivesGreater alcohol useProblem drinking groupInfluence alcohol usePhysical painInsula activationDrinking severityGo/NoGo taskNeural underpinningsPutamen responseSocial drinkersBehavioral measuresAvoidance performanceBehavioral resultsFunctional connectivityDrinking behavior
2020
Perceived burdensomeness and neural responses to ostracism in the Cyberball task
Le TM, Zhornitsky S, Wang W, Li CR. Perceived burdensomeness and neural responses to ostracism in the Cyberball task. Journal Of Psychiatric Research 2020, 130: 1-8. PMID: 32763557, PMCID: PMC7554229, DOI: 10.1016/j.jpsychires.2020.06.015.Peer-Reviewed Original ResearchConceptsCyberball taskInterpersonal needsIndividual differencesProsocial behaviorNeural responsesSocial interactionStronger neural responsesGreater brain activationDorsomedial prefrontal cortexMiddle frontal gyrusSocial exclusionResponse timeBrain activationBrain correlatesBehavioral performanceFMRI studyAnterior insulaFrontal gyrusSocial painBehavioral avoidanceAffective responsesBehavioral measuresNeural activationPrefrontal cortexEmotional distressNeural Responses to Reward in a Gambling Task: Sex Differences and Individual Variation in Reward-Driven Impulsivity
Li G, Zhang S, Le TM, Tang X, Li CR. Neural Responses to Reward in a Gambling Task: Sex Differences and Individual Variation in Reward-Driven Impulsivity. Cerebral Cortex Communications 2020, 1: tgaa025. PMID: 32864617, PMCID: PMC7446303, DOI: 10.1093/texcom/tgaa025.Peer-Reviewed Original ResearchGambling TaskNeural processesImpulse controlRegional activationSex differencesDorsal anterior cingulate cortexPrefrontal cortical activationAnterior cingulate cortexReaction timeHuman Connectome ProjectCautious respondingReward sensitivityIndividual variationNeural responsesBehavioral measuresAngular gyrusLonger reaction timesPrefrontal cortexImpulsivityCingulate cortexCortical activationConnectome ProjectHigher activationTaskReward