2008
Signal amplification on a DNA-tile-based biosensor with enhanced sensitivity
Lin C, Nangreave JK, Li Z, Liu Y, Yan H. Signal amplification on a DNA-tile-based biosensor with enhanced sensitivity. Nanomedicine 2008, 3: 521-528. PMID: 18694314, DOI: 10.2217/17435889.3.4.521.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateBiosensing TechniquesDNADNA, ViralNanotechnologyReproducibility of ResultsSevere acute respiratory syndrome-related coronavirusConceptsHybridization chain reactionSignal amplificationSelf-assembled DNAMultiplexed biosensingFluorescence enhancementNanomedical applicationsSensitive detectionDetection probeConfocal fluorescence microscopySignal amplifierImprovement of sensitivityDetection sensitivityOrders of magnitudeEnhanced sensitivityBiosensorBiosensingFluorescence microscopyNanoarraysSuccessful detectionReactionMicroscopyVersatilityDetection targetProbeDetection
2007
Self-Assembled Combinatorial Encoding Nanoarrays for Multiplexed Biosensing
Lin C, Liu Y, Yan H. Self-Assembled Combinatorial Encoding Nanoarrays for Multiplexed Biosensing. Nano Letters 2007, 7: 507-512. PMID: 17298017, PMCID: PMC1963466, DOI: 10.1021/nl062998n.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiosensing TechniquesCattleDNAEquipment DesignMicroarray AnalysisNanotechnologyOligonucleotide Array Sequence AnalysisConceptsDifferent molecular probesMultiplexed biosensingNucleic acid probesSensitive detectionMolecular probesMultiplexed detectionAcid probesDNA hybridizationBinding reactionNucleic acidsFluorescent dyeInterprobe distanceDisease diagnosticsSensor platformMoleculesMultiple DNA sequencesTwo-dimensional arraySmall amountBioconjugationBiosensingNanoarraysAptamerDyeProbeNanotiles
2006
Self‐Assembled Signaling Aptamer DNA Arrays for Protein Detection
Lin C, Katilius E, Liu Y, Zhang J, Yan H. Self‐Assembled Signaling Aptamer DNA Arrays for Protein Detection. Angewandte Chemie International Edition 2006, 45: 5296-5301. PMID: 16847867, DOI: 10.1002/anie.200600438.Peer-Reviewed Original ResearchMeSH KeywordsAptamers, NucleotideBase SequenceBiosensing TechniquesFluorescenceHumansNanostructuresSensitivity and SpecificityThrombin