2024
Lisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial
Grilo C, Ivezaj V, Yurkow S, Tek C, Wiedemann A, Gueorguieva R. Lisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2024, 54: 3334-3344. PMID: 39258475, PMCID: PMC11496227, DOI: 10.1017/s003329172400148x.Peer-Reviewed Original ResearchEating-disorder psychopathologyBinge-eating disorderMaintenance treatmentAcute treatmentBinge-eating remission ratesCognitive-behavioral therapyEfficacy of lisdexamfetamineSignificant weight gainDouble-blind placebo-controlled trialAcute respondersLisdexamfetamine treatmentPsychopathological outcomesPosttreatment assessmentLisdexamfetaminePlacebo-controlled trialRandomized double-blind placebo-controlled trialSingle-site trialAssociated with significant weight lossPsychopathologyBinge-eatingRemission rateWeight lossPlaceboRelapse rateControl researchThe impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction
Hazan H, Ferrara M, Riley S, Li F, Zhou B, Kline E, Gibbs-Dean T, Karmani S, Tayfur S, Tek C, Keshavan M, Srihari V. The impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction. Schizophrenia Research 2024, 264: 457-461. PMID: 38266513, PMCID: PMC10923115, DOI: 10.1016/j.schres.2024.01.022.Peer-Reviewed Original ResearchConceptsCoordinated specialty careDuration of untreated psychosisImpact of early detectionEarly detectionEarly detection campaignsSpecialty careAdjustment scoresCampaign yearDetection campaignsMediation analysisEffects of EDRegression modelsCareUntreated psychosisPositive symptomsGAFPatientsSalutary effects
2023
The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service
Ferrara M, Guloksuz S, Hazan H, Li F, Tek C, Sykes L, Riley S, Keshavan M, Srihari V. The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service. Schizophrenia Research 2023, 260: 198-204. PMID: 37688984, DOI: 10.1016/j.schres.2023.08.005.Peer-Reviewed Original ResearchConceptsFirst-episode psychosis servicesLength of stayUntreated psychosisPsychiatric hospitalizationFirst-episode servicesDuration of hospitalizationIncidence rate ratiosNon-affective psychosisNew Haven areaPoisson regression modelsPatient characteristicsHospitalization ratesRecent onsetMedical recordsHospitalizationEffect of durationNegative binomial regressionSpecialized treatmentPsychosisRate ratioBinomial regressionAdmissionDUPEnrollmentFirst year
2022
Corrigendum to: Reducing the Duration of Untreated Psychosis (DUP) in a US Community: A Quasi-Experimental Trial
Srihari V, Ferrara M, Li F, Kline E, Gülöksüz S, Pollard J, Cahill J, Mathis W, Sykes L, Walsh B, McDermott G, Seidman L, Gueorguieva R, Woods S, Tek C, Keshavan M. Corrigendum to: Reducing the Duration of Untreated Psychosis (DUP) in a US Community: A Quasi-Experimental Trial. Schizophrenia Bulletin Open 2022, 3: sgac020. PMID: 39144776, PMCID: PMC11206056, DOI: 10.1093/schizbullopen/sgac020.Peer-Reviewed Original Research
2020
O1.2. REDUCING THE DURATION OF UNTREATED PSYCHOSIS IN A U.S. CATCHMENT: THE MINDMAP CAMPAIGN
Srihari V, Ferrara M, Kline E, Li F, Burke S, Cahill J, Guloksuz S, Woods S, Tek C, Keshavan M. O1.2. REDUCING THE DURATION OF UNTREATED PSYCHOSIS IN A U.S. CATCHMENT: THE MINDMAP CAMPAIGN. Schizophrenia Bulletin 2020, 46: s1-s1. PMCID: PMC7233978, DOI: 10.1093/schbul/sbaa028.001.Peer-Reviewed Original Research
2019
31.1 COMBINING EXERCISE PHYSIOLOGY, RECREATIONAL THERAPY, VIRTUAL REALITY GAMING TECHNOLOGY, AND PSYCHOSOCIAL REHABILITATION TO PROMOTE PHYSICAL EXERCISE IN SERIOUS MENTAL ILLNESS
Choi J, Taylor B, Fiszdon J, Astur R, Haber L, Shagan D, Tek C, Kurtz M, Pearlson G. 31.1 COMBINING EXERCISE PHYSIOLOGY, RECREATIONAL THERAPY, VIRTUAL REALITY GAMING TECHNOLOGY, AND PSYCHOSOCIAL REHABILITATION TO PROMOTE PHYSICAL EXERCISE IN SERIOUS MENTAL ILLNESS. Schizophrenia Bulletin 2019, 45: s139-s140. PMCID: PMC6455379, DOI: 10.1093/schbul/sbz022.127.Peer-Reviewed Original ResearchEffects of Curcumin on Cognitive Functioning and Inflammatory State in Schizophrenia
Kucukgoncu S, Guloksuz S, Tek C. Effects of Curcumin on Cognitive Functioning and Inflammatory State in Schizophrenia. Journal Of Clinical Psychopharmacology 2019, 1. DOI: 10.1097/00004714-900000000-98602.Peer-Reviewed Original Research
2017
Alpha‐lipoic acid (ALA) as a supplementation for weight loss: results from a meta‐analysis of randomized controlled trials
Kucukgoncu S, Zhou E, Lucas K, Tek C. Alpha‐lipoic acid (ALA) as a supplementation for weight loss: results from a meta‐analysis of randomized controlled trials. Obesity Reviews 2017, 18: 594-601. PMID: 28295905, PMCID: PMC5523816, DOI: 10.1111/obr.12528.Peer-Reviewed Original ResearchConceptsAlpha-lipoic acidBody mass indexAlpha-lipoic acid treatmentPlacebo groupWeight lossEffect of ALASignificant short-term weight lossShort-term weight lossModest weight lossPlacebo treatment groupsPlacebo-controlled studyWeight changeAnti-obesity propertiesSystematic literature searchMeta-regression analysisMass indexSignificant morbidityALA doseBMI changeLong-term benefitsWeight managementBMI differencesTreatment groupsMortality rateStudy duration207. The Synergistic Effects of Physical and Cognitive Exercise in Schizophrenia
Choi J, Taylor B, Tek C, Kurtz M, Fiszdon J, Thime W, Dewberry M, Haber L, Assaf M, Pearlson G. 207. The Synergistic Effects of Physical and Cognitive Exercise in Schizophrenia. Schizophrenia Bulletin 2017, 43: s106-s106. PMCID: PMC5475743, DOI: 10.1093/schbul/sbx021.285.Peer-Reviewed Original Research178.3 Mindmap: A Population-Based Approach to Early Detection of Psychosis in the United States
Srihari V, Guloksuz S, Li F, Tek C, Woods S, Pollard J, Cahill J, Keshavan M, Seidman L. 178.3 Mindmap: A Population-Based Approach to Early Detection of Psychosis in the United States. Schizophrenia Bulletin 2017, 43: s95-s95. PMCID: PMC5475714, DOI: 10.1093/schbul/sbx021.255.Peer-Reviewed Original Research
2016
Integrated Health Care
Annamalai A, Tek C, Sernyak M, Cole R, Steiner J. Integrated Health Care. 2016, 63-80. DOI: 10.1093/med/9780190214678.003.0005.Peer-Reviewed Original ResearchEarly Intervention and Prevention for Psychotic Disorders
Pollard J, Tek C, Woods S, McGlashan T, Srihari V. Early Intervention and Prevention for Psychotic Disorders. 2016, 155-170. DOI: 10.1093/med/9780190214678.003.0010.Peer-Reviewed Original Research
2012
Managing Medication Effects on Body Weight: Do Behavioral Interventions Work?
Ratliff J, Reutenauer E, Tek C. Managing Medication Effects on Body Weight: Do Behavioral Interventions Work? FOCUS The Journal Of Lifelong Learning In Psychiatry 2012, 10: 130-139. DOI: 10.1176/appi.focus.10.2.130.Peer-Reviewed Original ResearchBody weightMental illnessBehavioral modification interventionsSevere mental illnessQuality of lifeLifestyle interventionPsychotropic medicationsMedication effectsObesity riskPsychiatric symptomsPsychiatric careCognitive impairmentModification interventionsAvailable evidenceBehavioral interventionsObesityInterventionWeight reductionBehavioral changesIllnessRiskMedicationsPatientsSymptomsDiagnosis
2011
Pharmacological Treatment of Obesity
Tek C, Ratliff J, Chwastiak L. Pharmacological Treatment of Obesity. Psychiatric Annals 2011, 41: 489-495. DOI: 10.3928/00485713-20110921-08.Peer-Reviewed Original ResearchIndividuals with schizophrenia consume more calories while following a similar diet pattern as the general population
Ratliff J, Palmese L, Reutenauer E, Liskov E, Tek C. Individuals with schizophrenia consume more calories while following a similar diet pattern as the general population. The FASEB Journal 2011, 25: 991.1-991.1. DOI: 10.1096/fasebj.25.1_supplement.991.1.Peer-Reviewed Original ResearchBody mass indexNHANES groupMore caloriesSchizophrenia groupPrevalence of obesityCoronary heart diseaseNutrition Examination SurveySchizophrenic individualsLower household incomeMetabolic syndromeWaist circumferenceMass indexExamination SurveyDiet recallHeart diseaseNational HealthAntipsychotic drugsSample patientsAnthropometric measurementsGeneral populationSchizophrenia patientsDiet patternReference groupVulnerable populationsSchizophrenia
2009
Public-Academic Partnerships: Early Intervention for Psychotic Disorders in a Community Mental Health Center
Srihari V, Breitborde N, Pollard J, Tek C, Hyman L, Frisman L, McGlashan T, Jacobs S, Woods S. Public-Academic Partnerships: Early Intervention for Psychotic Disorders in a Community Mental Health Center. Psychiatric Services 2009, 60: 1426-1428. DOI: 10.1176/ps.2009.60.11.1426.Peer-Reviewed Original ResearchThe unchanging mortality gap for people with schizophrenia
Chwastiak LA, Tek C. The unchanging mortality gap for people with schizophrenia. The Lancet 2009, 374: 590-592. PMID: 19595448, DOI: 10.1016/s0140-6736(09)61072-2.Peer-Reviewed Original Research
2007
A pilot study of a weight management program with food provision in schizophrenia
Jean-Baptiste M, Tek C, Liskov E, Chakunta UR, Nicholls S, Hassan AQ, Brownell KD, Wexler BE. A pilot study of a weight management program with food provision in schizophrenia. Schizophrenia Research 2007, 96: 198-205. PMID: 17628437, DOI: 10.1016/j.schres.2007.05.022.Peer-Reviewed Original ResearchConceptsWeight lossSignificant medical risksMeaningful weight lossWeight loss programWeight management programSevere mental illnessSerious medical problemLifestyle modificationComorbid obesityLoss programPilot trialGeneral populationMetabolic indicesCognitive impairmentMental illnessMedical riskMedical problemsWeight gainObesityPilot studySpecific populationsSchizophreniaBehavioral programHealthy foodsReplacement program
2005
Schizophrenia: Clinical Features and Psychopathology Concepts
Kirkpatrick B, Tek C. Schizophrenia: Clinical Features and Psychopathology Concepts; in Kaplan and Sadock’s Comprehensive Textbook of Psychiatry/VIIIth ed. Eds: Sadock BJ and Sadock VA, Lippincott Williams and Wilkins, Philadelphia, 2005Peer-Reviewed Original Research
2003
Letter to the editor. Substance abuse and the heterogeneity of schizophrenia a population-based study
Messias E, Tek C, Kirkpatrick B. Letter to the editor. Substance abuse and the heterogeneity of schizophrenia a population-based study. Schizophrenia Research 2003, 62: 293-294. PMID: 12837529, DOI: 10.1016/s0920-9964(02)00212-8.Peer-Reviewed Original Research