2024
Barriers to and facilitators of improving physical activity and nutrition behaviors during chemotherapy for breast cancer: a sequential mixed methods study
Puklin L, Irwin M, Sanft T, Ferrucci L, Harrigan M, McGowan C, Cartmel B, Zupa M, Winer E, Deyling M, Ligibel J, Basen-Engquist K, Spiegelman D, Sharifi M. Barriers to and facilitators of improving physical activity and nutrition behaviors during chemotherapy for breast cancer: a sequential mixed methods study. Supportive Care In Cancer 2024, 32: 590. PMID: 39141176, DOI: 10.1007/s00520-024-08789-5.Peer-Reviewed Original ResearchConceptsPhysical activityLifestyle interventionSelf-reported PA questionnaireSelf-reported diet qualityBreast cancerHealthy Eating Index-2015Stage I-III breast cancerBenefits of PASequential mixed methods studyI-III breast cancerChemotherapy-related symptomsMixed methods studyThematic content analysisBehavioral goalsSense of controlBody mass indexPA questionnaireSemi-structured interviewsMean body mass indexTranscribed verbatimIntervention armTailored educationDiet qualityNutritional behaviorMental benefits
2023
Effect of Exercise on Chemotherapy-Induced Peripheral Neuropathy Among Patients Treated for Ovarian Cancer
Cao A, Cartmel B, Li F, Gottlieb L, Harrigan M, Ligibel J, Gogoi R, Schwartz P, Esserman D, Irwin M, Ferrucci L. Effect of Exercise on Chemotherapy-Induced Peripheral Neuropathy Among Patients Treated for Ovarian Cancer. JAMA Network Open 2023, 6: e2326463. PMID: 37526937, PMCID: PMC10394582, DOI: 10.1001/jamanetworkopen.2023.26463.Peer-Reviewed Original ResearchConceptsChemotherapy-induced peripheral neuropathyAerobic exercise interventionAttention control armExercise intervention armExercise interventionOvarian cancerControl armIntervention armSecondary analysisCIPN symptomsPeripheral neuropathyLifestyle StudyTreatment of CIPNModerate-intensity aerobic exerciseStandard oncology careEffects of exerciseSevere adverse effectsBetween-group differencesAmerican Cancer SocietyQuality of lifeAttention controlCIPN severityPrimary outcomeOncology careAerobic exercise
2022
Exercise adherence in a randomized controlled trial of exercise on quality of life in ovarian cancer survivors
Cao A, Cartmel B, Li F, Gottlieb L, Harrigan M, Ligibel J, Gogoi R, Schwartz P, Irwin M, Ferrucci L. Exercise adherence in a randomized controlled trial of exercise on quality of life in ovarian cancer survivors. Journal Of Cancer Survivorship 2022, 17: 535-543. PMID: 36550261, PMCID: PMC10038915, DOI: 10.1007/s11764-022-01325-6.Peer-Reviewed Original ResearchConceptsOvarian cancer survivorsMin/weekCancer survivorsExercise goalsCancer recurrenceCounseling sessionsSession attendanceExercise adherenceHigher baseline activity levelsWeekly exercise durationTrial of exerciseMean exercise timeVigorous-intensity exerciseBaseline activity levelsQuality of lifeMore counseling sessionsExercise interventionExercise durationWeek exerciseLifestyle StudyExercise timeOvarian cancerNumber of sessionsCounseling intensitySurvivors
2021
Randomized trial of exercise on depressive symptomatology and brain derived neurotrophic factor (BDNF) in ovarian cancer survivors: The Women's Activity and Lifestyle Study in Connecticut (WALC)
Cartmel B, Hughes M, Ercolano EA, Gottlieb L, Li F, Zhou Y, Harrigan M, Ligibel JA, von Gruenigen VE, Gogoi R, Schwartz PE, Risch HA, Lu L, Irwin ML. Randomized trial of exercise on depressive symptomatology and brain derived neurotrophic factor (BDNF) in ovarian cancer survivors: The Women's Activity and Lifestyle Study in Connecticut (WALC). Gynecologic Oncology 2021, 161: 587-594. PMID: 33773809, PMCID: PMC8085084, DOI: 10.1016/j.ygyno.2021.02.036.Peer-Reviewed Original ResearchConceptsOvarian cancer survivorsCES-D scoresCancer survivorsOvarian cancerDepressive symptomatologyAC armStage III/IV ovarian cancerBaseline CES-D scoreTrial of exerciseEpidemiologic Studies Depression ScaleOvarian cancer patientsEffects of exerciseSix-month changesPrevalent mental disordersLower depressive symptomsExercise armSerum BrainNeurotrophin factorRandomized trialsNeurotrophic factorCancer patientsLifestyle StudyDepression ScalePhysical activityDepressive symptoms
2020
Skin carotenoids are inversely associated with adiposity in breast cancer survivors
Cartmel B, Anderson C, Irwin ML, Harrigan M, Sanft T, Li F, Gellermann W, Ermakov IV, Ferrucci LM. Skin carotenoids are inversely associated with adiposity in breast cancer survivors. Nutrition Research 2020, 79: 77-86. PMID: 32650223, PMCID: PMC7409553, DOI: 10.1016/j.nutres.2020.05.012.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsSkin carotenoid scoreUsual care groupCancer survivorsSkin carotenoidsBody fatCare groupSerum biomarkersAdiposity measuresLog C-reactive protein levelsBaseline percent body fatObese breast cancer survivorsC-reactive protein levelsDual-energy X-ray absorptiometryStrong associationBreast cancer patientsWeight loss trialStudy of overweightTotal body fatPercent body fatX-ray absorptiometryLog leptinPoor outcomeCancer patientsHip circumference
2018
Concordance of cancer registry and self-reported race, ethnicity, and cancer type: a report from the American Cancer Society’s studies of cancer survivors
Layne TM, Ferrucci LM, Jones BA, Smith T, Gonsalves L, Cartmel B. Concordance of cancer registry and self-reported race, ethnicity, and cancer type: a report from the American Cancer Society’s studies of cancer survivors. Cancer Causes & Control 2018, 30: 21-29. PMID: 30392148, DOI: 10.1007/s10552-018-1091-3.Peer-Reviewed Original ResearchLymphedema in ovarian cancer survivors: Assessing diagnostic methods and the effects of physical activity
Iyer NS, Cartmel B, Friedman L, Li F, Zhou Y, Ercolano E, Harrigan M, Gottlieb L, McCorkle R, Schwartz PE, Irwin ML. Lymphedema in ovarian cancer survivors: Assessing diagnostic methods and the effects of physical activity. Cancer 2018, 124: 1929-1937. PMID: 29437202, DOI: 10.1002/cncr.31239.Peer-Reviewed Original ResearchConceptsLower limb lymphedemaOvarian cancer survivorsCancer survivorsSelf-report questionnairesSide effectsSpecialist evaluationCancer treatmentDiagnostic methodsRandomized exercise interventionTrial of exerciseBody mass indexPhysical activity recommendationsEffects of exerciseOvarian cancer treatmentGynecologic cancer treatmentLymphedema prevalenceLymphedema specialistExercise groupExercise interventionDifferent diagnostic methodsMass indexBaseline prevalenceActivity recommendationsOvarian cancerLimb lymphedema
2017
Randomized Trial of Exercise on Quality of Life in Women With Ovarian Cancer: Women’s Activity and Lifestyle Study in Connecticut (WALC)
Zhou Y, Cartmel B, Gottlieb L, Ercolano EA, Li F, Harrigan M, McCorkle R, Ligibel JA, von Gruenigen VE, Gogoi R, Schwartz PE, Risch HA, Irwin ML. Randomized Trial of Exercise on Quality of Life in Women With Ovarian Cancer: Women’s Activity and Lifestyle Study in Connecticut (WALC). Journal Of The National Cancer Institute 2017, 109: djx072. PMID: 30053074, PMCID: PMC6515522, DOI: 10.1093/jnci/djx072.Peer-Reviewed Original ResearchMeSH KeywordsConnecticutExerciseFemaleHumansLife StyleMiddle AgedOvarian NeoplasmsQuality of LifeSurvivorsConceptsCancer-related fatigueOvarian cancer survivorsOvarian cancerCancer survivorsExercise interventionPhysical HRQoLCommunity-based exercise programSix-month RCTHealth-related qualityPrimary care providersTreatment side effectsGroup differencesSix-month assessmentQuality of lifeExercise armOverall survivalHigher HRQoLExercise programMental HRQOLRandomized trialsLifestyle StudyControl armFatigue scoresHRQoLPhysical activity
2016
Health-related quality of life in ovarian cancer survivors: Results from the American Cancer Society's Study of Cancer Survivors — I
Zhou Y, Irwin ML, Ferrucci LM, McCorkle R, Ercolano EA, Li F, Stein K, Cartmel B. Health-related quality of life in ovarian cancer survivors: Results from the American Cancer Society's Study of Cancer Survivors — I. Gynecologic Oncology 2016, 141: 543-549. PMID: 27072805, PMCID: PMC4913461, DOI: 10.1016/j.ygyno.2016.04.006.Peer-Reviewed Original ResearchConceptsOvarian cancer survivorsGreater symptom burdenAmerican Cancer Society's StudyHealth-related qualityCancer survivorsSymptom burdenDisease recurrencePhysical functioningTwo yearsOne-yearPredictors of HRQOLNumber of comorbiditiesHigher disease stagePhysical HRQoL scoresPoor mental functioningSubset of participantsMental health issuesMental functioningMore comorbiditiesHRQoL scoresClinical factorsLower HRQoLDisease stageHRQoL dataSecondary data analysis
2013
Single v. multiple measures of skin carotenoids by resonance Raman spectroscopy as a biomarker of usual carotenoid status
Scarmo S, Cartmel B, Lin H, Leffell DJ, Ermakov IV, Gellermann W, Bernstein PS, Mayne ST. Single v. multiple measures of skin carotenoids by resonance Raman spectroscopy as a biomarker of usual carotenoid status. British Journal Of Nutrition 2013, 110: 911-917. PMID: 23351238, PMCID: PMC3696054, DOI: 10.1017/s000711451200582x.Peer-Reviewed Original ResearchConceptsSkin carotenoid statusRecent sun exposureCarotenoid statusSkin carotenoidsSun exposureRR measuresFruit/vegetable intakeLower carotenoid statusSeason of measurementMean ageNon-invasive methodVegetable intakeInverse associationDietary dataTime pointsSignificant predictorsMultiple measuresPositive associationIntakeBiomarkersPresent studyStatusPredictorsAssociationExposure
2012
Employment experience of cancer survivors 2 years post-diagnosis in the Study of Cancer Survivors-I
Yu M, Ferrucci LM, McCorkle R, Ercolano E, Smith T, Stein KD, Cartmel B. Employment experience of cancer survivors 2 years post-diagnosis in the Study of Cancer Survivors-I. Journal Of Cancer Survivorship 2012, 6: 210-218. PMID: 22215311, DOI: 10.1007/s11764-011-0212-8.Peer-Reviewed Original ResearchConceptsCancer survivorsCancer survivors 2 yearsCancer survivor populationMultivariate logistic regressionSurvivors 2 yearsCancer survivors 2Lower household incomeSurvivorship yearsSurvivors 2Work status changesPsychosocial measuresOlder agePsychosocial characteristicsSurvivor populationLogistic regressionPotential predictorsSurvivorsWork-related experiencesLongitudinal studyStatus changesSurvivors' experiencesAdditional researchPredictorsYearsHealth
2011
Causal Attribution Among Cancer Survivors of the 10 Most Common Cancers
Ferrucci LM, Cartmel B, Turkman YE, Murphy ME, Smith T, Stein KD, McCorkle R. Causal Attribution Among Cancer Survivors of the 10 Most Common Cancers. Journal Of Psychosocial Oncology 2011, 29: 121-140. PMID: 21391066, PMCID: PMC3074193, DOI: 10.1080/07347332.2010.548445.Peer-Reviewed Original ResearchConceptsCausal attributionsSpecific causal attributionsCancer survivorsSurvivors' adjustmentMost cancer survivorsPsychosocial adjustmentCancer-related problemsPsychological factorsPsychosocial measuresAmerican Cancer Society's StudyAttributionBelief responsesCancer typesBeliefsParticipantsThematic categoriesAdditional researchSelf-administered questionnaireIndividual controlSurvivorsBiological factorsModifiable causesMultivariate adjustmentAdjustmentCommon cancer
2010
Noninvasive assessment of dermal carotenoids as a biomarker of fruit and vegetable intake
Mayne ST, Cartmel B, Scarmo S, Lin H, Leffell DJ, Welch E, Ermakov I, Bhosale P, Bernstein PS, Gellermann W. Noninvasive assessment of dermal carotenoids as a biomarker of fruit and vegetable intake. American Journal Of Clinical Nutrition 2010, 92: 794-800. PMID: 20685953, PMCID: PMC3133234, DOI: 10.3945/ajcn.2010.29707.Peer-Reviewed Original ResearchConceptsIntraclass correlation coefficientDermal carotenoidsDermal biopsiesRR measuresBiomarkers of fruitDietary carotenoid intakeVegetable intakeCarotenoid statusCarotenoid intakeStudy of nutritionNoninvasive assessmentBiopsyBiomarkersSkin pigmentationTotal carotenoidsHuman skinIntakeWkInner armLycopeneValid methodArm
2001
Predictors for cutaneous basal‐ and squamous‐cell carcinoma among actinically damaged adults
Foote J, Harris R, Giuliano A, Roe D, Moon T, Cartmel B, Alberts D. Predictors for cutaneous basal‐ and squamous‐cell carcinoma among actinically damaged adults. International Journal Of Cancer 2001, 95: 7-11. PMID: 11241303, PMCID: PMC2637530, DOI: 10.1002/1097-0215(20010120)95:1<7::aid-ijc1001>3.0.co;2-x.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaSkin cancerRisk factorsNon-melanoma skin cancerSCC incidence ratesAge 61 yearsRed hair colorGroup of menActinic lesionsBCC occurrencePlacebo groupChemoprevention trialsCutaneous basalBCC lesionsMale genderIncidence ratePrior historySun damageSubstantial incidenceOlder ageCancerFirst SCCExposure factorsAdult residenceCarcinoma
1999
Predictors of participant retention in two chemoprevention feasibility trials
Bowen D, Cartmel B, Barnett M, Goodman G, Omenn G. Predictors of participant retention in two chemoprevention feasibility trials. Annals Of Behavioral Medicine 1999, 21: 210-215. PMID: 10626026, DOI: 10.1007/bf02884835.Peer-Reviewed Original ResearchConceptsPilot study participantsPilot studyClinical trialsEfficacy trialsStudy participantsLong-term clinical trialsAsbestos-exposed participantsRetinol Efficacy TrialAsbestos-exposed workersHigh blood pressureCancer chemoprevention trialsGeneral health issuesFull-scale efficacy trialHigher baseline levelsMental health measuresRetention of participantsOnly significant predictorCurrent smokersBlood pressureChemoprevention trialsFeasibility trialPredictors of retentionPrevention StudyBaseline predictorsBaseline levelsPlasma Lycopene Concentrations in Humans Are Determined by Lycopene Intake, Plasma Cholesterol Concentrations and Selected Demographic Factors 1 , 2
Mayne S, Cartmel B, Silva F, Kim C, Fallon B, Briskin K, Zheng T, Baum M, Shor-Posner G, Goodwin W. Plasma Lycopene Concentrations in Humans Are Determined by Lycopene Intake, Plasma Cholesterol Concentrations and Selected Demographic Factors 1 , 2. Journal Of Nutrition 1999, 129: 849-854. PMID: 10203560, DOI: 10.1093/jn/129.4.849.Peer-Reviewed Original ResearchConceptsPlasma lycopene levelsPlasma lycopene concentrationsPlasma cholesterolLycopene levelsPlasma lycopeneLycopene intakeLycopene concentrationHigher plasma lycopene concentrationsNonwhite race/ethnicityDietary lycopene intakeCancer Prevention TrialMarital statusLow dietary intakeLower plasma cholesterolPlasma cholesterol concentrationLow plasma concentrationsLess vitamin CRace/ethnicityPrevention trialsDietary lycopeneTriglyceride levelsUnivariate analysisDietary intakeChronic diseasesPlasma concentrations
1997
Effect of retinol in preventing squamous cell skin cancer in moderate-risk subjects: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group.
Moon T, Levine N, Cartmel B, Bangert J, Rodney S, Dong Q, Peng Y, Alberts D. Effect of retinol in preventing squamous cell skin cancer in moderate-risk subjects: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group. Cancer Epidemiology Biomarkers & Prevention 1997, 6: 949-56. PMID: 9367069.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaNew squamous-cell carcinomasModerate-risk subjectsSkin cancerHazard ratioNew nonmelanoma skin cancersSquamous cell skin cancerIU of retinolNew skin cancersPlacebo-supplemented subjectsPrimary end pointNonmelanoma skin cancerFree-living subjectsEffect of retinolMedian followOral retinolBasal cell carcinoma skin cancersActinic keratosesRetinol supplementationCell carcinomaDaily supplementationAdverse symptomsEnd pointCancerNew BCCTrial of retinol and isotretinoin in skin cancer prevention: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group.
Levine N, Moon T, Cartmel B, Bangert J, Rodney S, Dong Q, Peng Y, Alberts D. Trial of retinol and isotretinoin in skin cancer prevention: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group. Cancer Epidemiology Biomarkers & Prevention 1997, 6: 957-61. PMID: 9367070.Peer-Reviewed Original ResearchConceptsCutaneous squamous cell carcinomaSquamous cell carcinomaBasal cell carcinomaNonmelanoma skin cancerCell carcinomaSkin cancerPlacebo-controlled trialHigh-risk subjectsSkin cancer preventionEffect of retinolOral retinolStudy clinicCancer preventionOutcome measuresIsotretinoinBeneficial effectsStudy periodRetinolTrialsCarcinomaCancerPreventionTotal numberParticipantsPlaceboRetinoids in prevention of skin cancer
Moon T, Levine N, Cartmel B, Bangert J. Retinoids in prevention of skin cancer. Cancer Letters 1997, 114: 203-205. PMID: 9103292, DOI: 10.1016/s0304-3835(97)04663-6.Peer-Reviewed Original ResearchConceptsBasal cell skin cancerModerate-risk subjectsPrior skin cancersHigh-risk subjectsRisk subjectsSkin cancerB trialSquamous cell skin cancerSquamous cell cancerEffects of retinoidsActinic keratosesCell cancerClinical trialsIntervention durationCancerTrialsRetinolRetinoidsPlaceboIncidencePreventionSubjectsSignificant benefitsIsotretinoinKeratoses
1995
Design and recruitment for retinoid skin cancer prevention (SKICAP) trials. The Southwest Skin Cancer Prevention Study Group.
Moon T, Levine N, Cartmel B, Bangert J, Rodney S, Schreiber M, Peng Y, Ritenbaugh C, Meyskens F, Alberts D. Design and recruitment for retinoid skin cancer prevention (SKICAP) trials. The Southwest Skin Cancer Prevention Study Group. Cancer Epidemiology Biomarkers & Prevention 1995, 4: 661-9. PMID: 8547834.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaBasal cell carcinomaSkin cancer prevention trialCancer Prevention TrialHigh-risk individualsB participantsPrevention trialsCell carcinomaDaily supplementationPlacebo-controlled clinical trialCutaneous squamous cell carcinomaSkin cancer incidenceDermatologist referralCancer RegistryAdditional clinicsCancer incidenceClinical trialsStudy groupSkin cancerB trialClinicTrialsEnrollment goalsCarcinomaIncidence