2024
The role of C4d and donor specific antibodies in face and hand transplantation—a systematic review
Huelsboemer L, Moscarelli J, Dony A, Boroumand S, Kochen A, Knoedler L, Yu C, Hauc S, Stögner V, Formica R, Lian C, Murphy G, Pomahac B, Kauke-Navarro M. The role of C4d and donor specific antibodies in face and hand transplantation—a systematic review. Frontiers In Transplantation 2024, 3: 1442006. PMID: 39291278, PMCID: PMC11405992, DOI: 10.3389/frtra.2024.1442006.Peer-Reviewed Original ResearchDonor-specific antibodiesSerum donor-specific antibodiesAntibody-mediated rejectionHigher rejection gradesVascularized composite allotransplantationC4d depositionRejection gradeCellular rejectionRejection episodesSpecific antibodiesDonor-specific antibody statusManagement of antibody-mediated rejectionFace transplantationAcute cellular rejectionAcute rejection episodesAssociated with high gradeTime of biopsyAntibody mediated rejectionFisher's exact testMann-Whitney U testSystematic review of electronic databasesMechanisms of rejectionSystematic reviewReview of electronic databasesC4d stainingQuality of life and satisfaction after breast augmentation: A systematic review and meta-analysis of Breast-Q patient-reported outcomes
Knoedler S, Knoedler L, Kauke-Navarro M, Alfertshofer M, Obed D, Broer N, Kim B, Könneker S, Panayi A, Hundeshagen G, Kneser U, Pomahac B, Haug V. Quality of life and satisfaction after breast augmentation: A systematic review and meta-analysis of Breast-Q patient-reported outcomes. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024, 95: 300-318. PMID: 38945110, DOI: 10.1016/j.bjps.2024.06.016.Peer-Reviewed Original ResearchPhysical well-beingSexual well-beingWell-beingPatient-reported physical well-beingPatient reportsMeta-analysisPsychosocial well-beingPatient-reported outcomesPatient-reported quality of lifeBreast augmentationQuality of lifeHigher QoLPairwise meta-analysisA systematic reviewPatients' QoLPatient satisfactionSystematic reviewEligibility criteriaPRISMA guidelinesPostoperative follow-up timeQoLQuantitative synthesisFollow-up timeSubgroup analysisSatisfactionImmunosuppressive strategies in face and hand transplantation: a comprehensive systematic review of current therapy regimens and outcomes
Huelsboemer L, Boroumand S, Kochen A, Dony A, Moscarelli J, Hauc S, Stögner V, Formica R, Pomahac B, Kauke-Navarro M. Immunosuppressive strategies in face and hand transplantation: a comprehensive systematic review of current therapy regimens and outcomes. Frontiers In Transplantation 2024, 3: 1366243. PMID: 38993787, PMCID: PMC11235358, DOI: 10.3389/frtra.2024.1366243.Peer-Reviewed Original ResearchCMV infectionImmunosuppressive regimensImmunosuppressive strategiesTransplant recipientsIncidence of rejection episodesClinical CMV infectionTriple maintenance therapyIncidence of rejectionEpisodes of rejectionIndividualized immunosuppressive regimensEffective immunosuppressive therapySystematic reviewFace transplant patientsHand transplant recipientsHand transplantationFacial graftImmunosuppressive therapyMaintenance therapyRejection episodesFacial mucosaGraft lossGraft rejectionTherapy regimensTransplant patientsRenal failure
2022
Patient-Reported Outcomes After Reduction Mammoplasty Using BREAST-Q: A Systematic Review and Meta-Analysis
Wang A, Panayi A, Fischer S, Diehm Y, Tapking C, Hundeshagen G, Kneser U, Mastroianni M, Pomahac B, Haug V. Patient-Reported Outcomes After Reduction Mammoplasty Using BREAST-Q: A Systematic Review and Meta-Analysis. Aesthetic Surgery Journal 2022, 43: np231-np241. PMID: 36411260, DOI: 10.1093/asj/sjac293.Peer-Reviewed Original Research
2020
Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review
Safi AF, Kauke M, Nelms L, Palmer WJ, Tchiloemba B, Kollar B, Haug V, Pomahač B. Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 74: 327-335. PMID: 33229219, DOI: 10.1016/j.bjps.2020.10.003.Peer-Reviewed Original ResearchConceptsLocal immunosuppressionSystematic reviewAllograft survivalComposite allotransplantationAllograft survival dataCell-based therapy strategiesImproved allograft survivalMain immunosuppressive agentMeta-Analyses (PRISMA) guidelinesPreclinical animal studiesPreferred Reporting ItemsMalignant side effectsImmunosuppressive agentsPreclinical dataSignificant prolongationRat modelHuman trialsExclusion criteriaImmunosuppressionSide effectsAnimal studiesReporting ItemsPubMed databaseSystemic toxicityTherapy strategiesUse of venous couplers in microsurgical lower extremity reconstruction: A systematic review and meta‐analysis
Haug V, Panayi A, Kadakia N, Abdulrazzak O, Endo Y, Udeh K, Kollar B, Hundeshagen G, Pomahac B, Kneser U, Hirche C. Use of venous couplers in microsurgical lower extremity reconstruction: A systematic review and meta‐analysis. Microsurgery 2020, 41: 50-60. PMID: 32227603, DOI: 10.1002/micr.30581.Peer-Reviewed Original ResearchConceptsLower limb reconstructionHand-sewn anastomosisSystematic reviewLimb reconstructionVenous couplerMicrosurgical lower extremity reconstructionMore surgical complicationsAdditional prospective studiesMeta-Analyses (PRISMA) guidelinesLower extremity reconstructionFree tissue transferFull-text reviewQuality of reportingWeb of ScienceMicrovascular complicationsSurgical complicationsArterial compromiseCochrane CollaborationProspective studyCase reportVenous anastomosisClinical trialsLower extremitiesSurgical techniqueInclusion criteriaAll hands on deck: Hand replantation versus transplantation
Heineman J, Bueno E, Kiwanuka H, Carty M, Sampson C, Pribaz J, Pomahac B, Talbot S. All hands on deck: Hand replantation versus transplantation. SAGE Open Medicine 2020, 8: 2050312120926351. PMID: 32537157, PMCID: PMC7268554, DOI: 10.1177/2050312120926351.Peer-Reviewed Original ResearchHand replantationAdverse events/side effectsSystematic reviewPatient satisfaction/qualityPost-operative considerationsDeterminants of outcomePre-operative considerationsMeta-Analyses (PRISMA) guidelinesSatisfaction/qualityPreferred Reporting ItemsBest possible outcomeUpper limb lossAcute amputationsSurgical repairHand transplantationSurgical techniqueOperative techniquePatient commitmentComplete amputationDaily livingForearm levelLimb lossPatient expectationsSide effectsBetter outcomes